Reversible, Allosteric Small-Molecule Inhibitors of Regulator of G Protein Signaling Proteins

Data Supplement

Files in this Data Supplement:

• Data Supplement - Supplemental Figure 1. Reaction scheme for the synthesis of CCG-63802 and CCG-63808.
  Supplemental Figure 2. Gαo is thermally stabilized in presence of nucleotide...
  Supplemental Figure 3. A) CCG-63802 and B) CCG-63808 are much less potent on a mutant form of RGS4 that lacks cysteine residues in the RH domain. Data are presented as mean +/- SEM from 3 separate FCPIA experiments.