GOID GO_term Cluster frequency Background frequency P-value Gene(s) annotated to the term Directly Annotated GOID List 51327 M phase of meiotic cell cycle "21 out of 63 genes, 33.3%" "148 out of 7159 background genes, 2.1%" 3.06E-18 PCH2/YBR186W:MSH5/YDL154W:ZIP1/YDR285W:MEI4/YER044C-A:DMC1/YER179W:HOP2/YGL033W:RMR1/YGL250W:RIM4/YHL024W:SPO13/YHR014W:SPO16/YHR153C:REC104/YHR157W:HOP1/YIL072W:IME2/YJL106W:RED1/YLR263W:REC114/YMR133W:SPO1/YNL012W:NDJ1/YOL104C:MEK1/YOR351C:MEI5/YPL121C:CSM4/YPL200W:REC8/YPR007C 6468:7130:7131:51177:6279:45876:707:45141:51598:40020:45132:7129:709:43085:10520:7126:6311:30435:70197:42138:30437 7126 meiosis "21 out of 63 genes, 33.3%" "148 out of 7159 background genes, 2.1%" 3.06E-18 PCH2/YBR186W:MSH5/YDL154W:ZIP1/YDR285W:MEI4/YER044C-A:DMC1/YER179W:HOP2/YGL033W:RMR1/YGL250W:RIM4/YHL024W:SPO13/YHR014W:SPO16/YHR153C:REC104/YHR157W:HOP1/YIL072W:IME2/YJL106W:RED1/YLR263W:REC114/YMR133W:SPO1/YNL012W:NDJ1/YOL104C:MEK1/YOR351C:MEI5/YPL121C:CSM4/YPL200W:REC8/YPR007C 6468:7130:7131:51177:6279:45876:707:45141:51598:40020:45132:7129:709:43085:10520:7126:6311:30435:70197:42138:30437 51321 meiotic cell cycle "21 out of 63 genes, 33.3%" "149 out of 7159 background genes, 2.1%" 3.55E-18 PCH2/YBR186W:MSH5/YDL154W:ZIP1/YDR285W:MEI4/YER044C-A:DMC1/YER179W:HOP2/YGL033W:RMR1/YGL250W:RIM4/YHL024W:SPO13/YHR014W:SPO16/YHR153C:REC104/YHR157W:HOP1/YIL072W:IME2/YJL106W:RED1/YLR263W:REC114/YMR133W:SPO1/YNL012W:NDJ1/YOL104C:MEK1/YOR351C:MEI5/YPL121C:CSM4/YPL200W:REC8/YPR007C 6468:7130:7131:51177:6279:45876:707:45141:51598:40020:45132:7129:709:43085:10520:7126:6311:30435:70197:42138:30437 7127 meiosis I "17 out of 63 genes, 27.0%" "81 out of 7159 background genes, 1.1%" 2.18E-17 MSH5/YDL154W:ZIP1/YDR285W:MEI4/YER044C-A:DMC1/YER179W:HOP2/YGL033W:RMR1/YGL250W:RIM4/YHL024W:SPO16/YHR153C:REC104/YHR157W:HOP1/YIL072W:RED1/YLR263W:REC114/YMR133W:NDJ1/YOL104C:MEK1/YOR351C:MEI5/YPL121C:CSM4/YPL200W:REC8/YPR007C 6468:7130:7131:51177:6279:707:45141:51598:45132:7129:709:43085:10520:7126:6311:30435:70197:42138:30437 279 M phase "23 out of 63 genes, 36.5%" "272 out of 7159 background genes, 3.8%" 4.82E-15 PCH2/YBR186W:MSH5/YDL154W:ZIP1/YDR285W:MEI4/YER044C-A:DMC1/YER179W:HOP2/YGL033W:RMR1/YGL250W:RIM4/YHL024W:SPO13/YHR014W:SPO16/YHR153C:REC104/YHR157W:HOP1/YIL072W:IME2/YJL106W:RED1/YLR263W:PDS5/YMR076C:REC114/YMR133W:SPO1/YNL012W:NDJ1/YOL104C:MEK1/YOR351C:MEI5/YPL121C:TFB2/YPL122C:CSM4/YPL200W:REC8/YPR007C 6468:7130:7131:51177:6279:45876:707:45141:51598:40020:45132:7129:709:7070:43085:7076:10520:7126:6311:30435:6367:70197:6289:42138:717:7064:30437 7131 reciprocal meiotic recombination "13 out of 63 genes, 20.6%" "47 out of 7159 background genes, 0.7%" 1.33E-14 MSH5/YDL154W:MEI4/YER044C-A:DMC1/YER179W:HOP2/YGL033W:RMR1/YGL250W:RIM4/YHL024W:SPO16/YHR153C:REC104/YHR157W:REC114/YMR133W:NDJ1/YOL104C:MEI5/YPL121C:CSM4/YPL200W:REC8/YPR007C 7130:7131:51177:6279:707:45141:45132:7129:709:10520:7126:6311:30435:70197:42138:30437 22403 cell cycle phase "23 out of 63 genes, 36.5%" "367 out of 7159 background genes, 5.1%" 3.59E-12 PCH2/YBR186W:MSH5/YDL154W:ZIP1/YDR285W:MEI4/YER044C-A:DMC1/YER179W:HOP2/YGL033W:RMR1/YGL250W:RIM4/YHL024W:SPO13/YHR014W:SPO16/YHR153C:REC104/YHR157W:HOP1/YIL072W:IME2/YJL106W:RED1/YLR263W:PDS5/YMR076C:REC114/YMR133W:SPO1/YNL012W:NDJ1/YOL104C:MEK1/YOR351C:MEI5/YPL121C:TFB2/YPL122C:CSM4/YPL200W:REC8/YPR007C 6468:7130:7131:51177:6279:45876:707:45141:51598:40020:45132:7129:709:7070:43085:7076:10520:7126:6311:30435:6367:70197:6289:42138:717:7064:30437 70192 chromosome organization involved in meiosis "8 out of 63 genes, 12.7%" "14 out of 7159 background genes, 0.2%" 1.53E-11 ZIP1/YDR285W:HOP2/YGL033W:SPO16/YHR153C:HOP1/YIL072W:RED1/YLR263W:NDJ1/YOL104C:CSM4/YPL200W:REC8/YPR007C 7130:7131:51177:45141:51598:45132:7129:43085:10520:70197:30437 7129 synapsis "8 out of 63 genes, 12.7%" "14 out of 7159 background genes, 0.2%" 1.53E-11 ZIP1/YDR285W:HOP2/YGL033W:SPO16/YHR153C:HOP1/YIL072W:RED1/YLR263W:NDJ1/YOL104C:CSM4/YPL200W:REC8/YPR007C 7130:7131:51177:45141:51598:45132:7129:43085:10520:70197:30437 22402 cell cycle process "23 out of 63 genes, 36.5%" "417 out of 7159 background genes, 5.8%" 5.56E-11 PCH2/YBR186W:MSH5/YDL154W:ZIP1/YDR285W:MEI4/YER044C-A:DMC1/YER179W:HOP2/YGL033W:RMR1/YGL250W:RIM4/YHL024W:SPO13/YHR014W:SPO16/YHR153C:REC104/YHR157W:HOP1/YIL072W:IME2/YJL106W:RED1/YLR263W:PDS5/YMR076C:REC114/YMR133W:SPO1/YNL012W:NDJ1/YOL104C:MEK1/YOR351C:MEI5/YPL121C:TFB2/YPL122C:CSM4/YPL200W:REC8/YPR007C 6468:7130:7131:51177:6279:45876:707:45141:51598:40020:45132:7129:709:7070:43085:7076:10520:7126:6311:30435:6367:70197:6289:42138:717:7064:30437 7049 cell cycle "24 out of 63 genes, 38.1%" "471 out of 7159 background genes, 6.6%" 8.07E-11 PCH2/YBR186W:MSH5/YDL154W:ZIP1/YDR285W:MEI4/YER044C-A:DMC1/YER179W:HOP2/YGL033W:RMR1/YGL250W:RIM4/YHL024W:SPO13/YHR014W:SPO16/YHR153C:REC104/YHR157W:ULP2/YIL031W:HOP1/YIL072W:IME2/YJL106W:RED1/YLR263W:PDS5/YMR076C:REC114/YMR133W:SPO1/YNL012W:NDJ1/YOL104C:MEK1/YOR351C:MEI5/YPL121C:TFB2/YPL122C:CSM4/YPL200W:REC8/YPR007C 6468:7130:7094:7131:51177:6279:45876:707:45141:51598:40020:45132:7129:16926:709:7070:43085:7076:10520:7126:6311:30261:6276:30435:6367:70197:6289:42138:717:7064:30437 40020 regulation of meiosis "8 out of 63 genes, 12.7%" "27 out of 7159 background genes, 0.4%" 1.03E-08 PCH2/YBR186W:SPO16/YHR153C:HOP1/YIL072W:IME2/YJL106W:RED1/YLR263W:NDJ1/YOL104C:MEK1/YOR351C:CSM4/YPL200W 6468:7130:7131:45141:51598:40020:45132:7129:43085:10520:7126:70197:30437 51445 regulation of meiotic cell cycle "8 out of 63 genes, 12.7%" "28 out of 7159 background genes, 0.4%" 1.44E-08 PCH2/YBR186W:SPO16/YHR153C:HOP1/YIL072W:IME2/YJL106W:RED1/YLR263W:NDJ1/YOL104C:MEK1/YOR351C:CSM4/YPL200W 6468:7130:7131:45141:51598:40020:45132:7129:43085:10520:7126:70197:30437 6310 DNA recombination "14 out of 63 genes, 22.2%" "163 out of 7159 background genes, 2.3%" 1.91E-08 MSH5/YDL154W:MEI4/YER044C-A:DMC1/YER179W:HOP2/YGL033W:RMR1/YGL250W:RIM4/YHL024W:SPO16/YHR153C:RTT107/YHR154W:REC104/YHR157W:REC114/YMR133W:NDJ1/YOL104C:MEI5/YPL121C:CSM4/YPL200W:REC8/YPR007C 7130:10526:6302:7131:51177:6279:707:45141:45132:7129:709:10520:7126:6311:30435:70197:42138:30437 10564 regulation of cell cycle process "9 out of 63 genes, 14.3%" "71 out of 7159 background genes, 1.0%" 1.99E-06 PCH2/YBR186W:SPO13/YHR014W:SPO16/YHR153C:HOP1/YIL072W:IME2/YJL106W:RED1/YLR263W:NDJ1/YOL104C:MEK1/YOR351C:CSM4/YPL200W 6468:7130:7131:51177:45876:45141:51598:40020:45132:7129:43085:10520:7126:70197:30437 9987 cellular process "60 out of 63 genes, 95.2%" "4769 out of 7159 background genes, 66.6%" 8.96E-06 ACS1/YAL054C:ACH1/YBL015W:PRX1/YBL064C:PCH2/YBR186W:RIB5/YBR256C:DUG2/YBR281C:ADY2/YCR010C:MSH5/YDL154W:NUS1/YDL193W:ADY3/YDL239C:ARO3/YDR035W:ZIP1/YDR285W:EAF1/YDR359C:MEI4/YER044C-A:DMC1/YER179W:GAT1/YFL021W:HOP2/YGL033W:PYC1/YGL062W:STR3/YGL184C:RMR1/YGL250W:RIM4/YHL024W:SPO13/YHR014W:SPO16/YHR153C:RTT107/YHR154W:REC104/YHR157W:ULP2/YIL031W:HOP1/YIL072W:SIP4/YJL089W:IME2/YJL106W:INO1/YJL153C:ECM17/YJR137C:PUT3/YKL015W:FOX2/YKR009C:GPI13/YLL031C:RNP1/YLL046C:AAT2/YLR027C:CFT2/YLR115W:RED1/YLR263W:CDC3/YLR314C:CAT2/YML042W:RPM2/YML091C:PDS5/YMR076C:REC114/YMR133W:HSC82/YMR186W:FKS3/YMR306W:SPO1/YNL012W:PKH2/YOL100W:NDJ1/YOL104C:HRP1/YOL123W:CRC1/YOR100C:MEK1/YOR351C:ALD4/YOR374W:CAR1/YPL111W:VPS30/YPL120W:MEI5/YPL121C:TFB2/YPL122C:CSM4/YPL200W:YIG1/YPL201C:REC8/YPR007C:APL4/YPR029C 6021:6397:45941:7131:9437:45324:6279:723:45876:6635:19740:45944:9073:9231:6631:6084:30433:1682:6281:55085:45722:30435:6367:45454:103:717:6458:16568:6067:19346:42254:6486:6468:902:30476:6808:51177:6094:7047:707:42147:6979:6661:6562:6740:6950:6114:10520:30010:19654:6083:6289:43248:6085:30437:910:6461:6396:34727:6457:7094:1:45141:7005:40020:709:43085:7076:15696:6846:7126:6311:42026:42138:32258:6506:7130:9086:16573:10526:6302:6412:1403:6896:42493:19547:51598:45132:7129:16926:7070:6532:7120:30261:6379:6276:70197:6357:6751:6378:16236:196:7064:16192 6259 DNA metabolic process "17 out of 63 genes, 27.0%" "417 out of 7159 background genes, 5.8%" 1.46E-05 MSH5/YDL154W:EAF1/YDR359C:MEI4/YER044C-A:DMC1/YER179W:HOP2/YGL033W:RMR1/YGL250W:RIM4/YHL024W:SPO16/YHR153C:RTT107/YHR154W:REC104/YHR157W:REC114/YMR133W:HSC82/YMR186W:NDJ1/YOL104C:MEI5/YPL121C:TFB2/YPL122C:CSM4/YPL200W:REC8/YPR007C 7131:6279:723:6281:30435:6367:717:6458:16568:51177:707:6950:10520:6289:43248:30437:6457:45141:709:7126:6311:42026:42138:7130:10526:6302:45132:7129:7070:70197 7130 synaptonemal complex assembly "4 out of 63 genes, 6.3%" "8 out of 7159 background genes, 0.1%" 8.68E-05 SPO16/YHR153C:HOP1/YIL072W:RED1/YLR263W:REC8/YPR007C 7131:51177:10520:30437:43085:7130:51598:7129 70193 synaptonemal complex organization "4 out of 63 genes, 6.3%" "9 out of 7159 background genes, 0.1%" 0.00016 SPO16/YHR153C:HOP1/YIL072W:RED1/YLR263W:REC8/YPR007C 7131:51177:10520:30437:43085:7130:51598:7129 51726 regulation of cell cycle "10 out of 63 genes, 15.9%" "161 out of 7159 background genes, 2.2%" 0.00027 PCH2/YBR186W:SPO13/YHR014W:SPO16/YHR153C:ULP2/YIL031W:HOP1/YIL072W:IME2/YJL106W:RED1/YLR263W:NDJ1/YOL104C:MEK1/YOR351C:CSM4/YPL200W 7131:45876:6468:51177:10520:30437:7094:45141:40020:43085:7126:7130:51598:45132:7129:16926:30261:6276:70197 51276 chromosome organization "14 out of 63 genes, 22.2%" "376 out of 7159 background genes, 5.3%" 0.00079 ACS1/YAL054C:ZIP1/YDR285W:EAF1/YDR359C:HOP2/YGL033W:SPO13/YHR014W:SPO16/YHR153C:ULP2/YIL031W:HOP1/YIL072W:RED1/YLR263W:PDS5/YMR076C:HSC82/YMR186W:NDJ1/YOL104C:CSM4/YPL200W:REC8/YPR007C 7131:723:45876:6281:6458:16568:51177:6950:10520:19654:43248:6085:30437:6457:7094:45141:43085:7076:42026:7130:16573:51598:45132:7129:16926:30261:6276:70197:7064 10520 regulation of reciprocal meiotic recombination "3 out of 63 genes, 4.8%" "5 out of 7159 background genes, 0.1%" 0.0015 SPO16/YHR153C:NDJ1/YOL104C:CSM4/YPL200W 7131:10520:30437:45141:7130:45132:7129:70197 33313 meiotic cell cycle checkpoint "3 out of 63 genes, 4.8%" "5 out of 7159 background genes, 0.1%" 0.0015 HOP1/YIL072W:RED1/YLR263W:MEK1/YOR351C 6468:43085:7126:7130:51598:7129 51324 prophase "3 out of 63 genes, 4.8%" "5 out of 7159 background genes, 0.1%" 0.0015 HOP1/YIL072W:RED1/YLR263W:MEK1/YOR351C 6468:43085:7126:7130:51598:7129 51598 meiotic recombination checkpoint "3 out of 63 genes, 4.8%" "5 out of 7159 background genes, 0.1%" 0.0015 HOP1/YIL072W:RED1/YLR263W:MEK1/YOR351C 6468:43085:7126:7130:51598:7129 7128 meiotic prophase I "3 out of 63 genes, 4.8%" "5 out of 7159 background genes, 0.1%" 0.0015 HOP1/YIL072W:RED1/YLR263W:MEK1/YOR351C 6468:43085:7126:7130:51598:7129 19752 carboxylic acid metabolic process "12 out of 63 genes, 19.0%" "338 out of 7159 background genes, 4.7%" 0.00714 ACS1/YAL054C:ACH1/YBL015W:ARO3/YDR035W:PYC1/YGL062W:STR3/YGL184C:SIP4/YJL089W:PUT3/YKL015W:FOX2/YKR009C:AAT2/YLR027C:CAT2/YML042W:CRC1/YOR100C:CAR1/YPL111W 9437:6635:45944:9073:6631:6084:45722:19346:6094:6562:6740:6083:19654:6085:9086:16573:1403:19547:6532:6357 6082 organic acid metabolic process "12 out of 63 genes, 19.0%" "338 out of 7159 background genes, 4.7%" 0.00714 ACS1/YAL054C:ACH1/YBL015W:ARO3/YDR035W:PYC1/YGL062W:STR3/YGL184C:SIP4/YJL089W:PUT3/YKL015W:FOX2/YKR009C:AAT2/YLR027C:CAT2/YML042W:CRC1/YOR100C:CAR1/YPL111W 9437:6635:45944:9073:6631:6084:45722:19346:6094:6562:6740:6083:19654:6085:9086:16573:1403:19547:6532:6357 42138 meiotic DNA double-strand break formation "3 out of 63 genes, 4.8%" "8 out of 7159 background genes, 0.1%" 0.00825 MEI4/YER044C-A:REC104/YHR157W:REC114/YMR133W 7131:30437:42138 8152 metabolic process "47 out of 63 genes, 74.6%" "3537 out of 7159 background genes, 49.4%" 0.0087 ACS1/YAL054C:ACH1/YBL015W:RIB5/YBR256C:DUG2/YBR281C:ADY2/YCR010C:MSH5/YDL154W:NUS1/YDL193W:ARO3/YDR035W:EAF1/YDR359C:MEI4/YER044C-A:DMC1/YER179W:GAT1/YFL021W:HOP2/YGL033W:PYC1/YGL062W:STR3/YGL184C:RMR1/YGL250W:RIM4/YHL024W:SPO16/YHR153C:RTT107/YHR154W:REC104/YHR157W:ULP2/YIL031W:SIP4/YJL089W:IME2/YJL106W:INO1/YJL153C:ECM17/YJR137C:PUT3/YKL015W:FOX2/YKR009C:GPI13/YLL031C:AAT2/YLR027C:CFT2/YLR115W:CAT2/YML042W:RPM2/YML091C:REC114/YMR133W:HSC82/YMR186W:PKH2/YOL100W:NDJ1/YOL104C:HRP1/YOL123W:CRC1/YOR100C:MEK1/YOR351C:ALD4/YOR374W:CAR1/YPL111W:VPS30/YPL120W:MEI5/YPL121C:TFB2/YPL122C:CSM4/YPL200W:YIG1/YPL201C:REC8/YPR007C 6021:6397:45941:7131:9437:45324:6279:723:6635:19740:45944:9073:9231:6631:6084:30433:1682:6281:55085:45722:30435:6367:103:717:6458:16568:6067:19346:6486:6468:6808:51177:6094:7047:707:42147:6661:6562:6740:6950:6114:10520:6083:19654:6289:43248:6085:30437:6396:34727:6457:7094:45141:7005:40020:709:15696:7126:6846:6311:42026:42138:32258:6506:7130:9086:10526:16573:6302:6412:1403:42493:19547:51598:45132:7129:16926:7070:6532:6379:30261:6276:70197:6357:6751:6378:16236:196