Macaque Proteome Response to Highly Pathogenic Avian Influenza and 1918 Reassortant Influenza Virus Infections
J. Virol. Brown et al. 84: 12058
Supplemental material
Files in this Data Supplement:
- Supplemental file 1 - Fig. S1 (Median z scores of spectral counts for each of the 8 clusters graphed relative to virus and time point.)
Fig. S2 (Pathology scores.)
Fig. S3 (Representative correlation analysis between proteomics and genomics z score values for HPAI.)
PDF file, 497K. - Supplemental file 2 - Table S1 (400 macaque proteins identified from LC-MS/MS analyses as increased in influenza virus-infected animals relative to uninfected controls.)
Zipped MS Excel file, 34K. - Supplemental file 3 - Table S2 (258 macaque proteins identified from LC-MS/MS analyses as decreased in influenza virus-infected animals relative to uninfected controls.)
Zipped Excel file, 25K. - Supplemental file 4 - Table S3 (z score values for 400 proteins that increased expression in infected animals relative to controls.)
Zipped Excel file, 42K. - Supplemental file 5 - Table S4 (Binning of the 400 proteins with increased expression into categories of “normal,” “core,” or “high,” as referenced in the discussion of the frequency histograms in Fig. 2, panels B to E.)
Zipped Excel file, 42K. - Supplemental file 6 - Table S5 (Listing of proteins in the heat map of Fig. 3, with z scores used in the clustering.)
Zipped Excel file, 45K. - Supplemental file 7 - Table S6 (Pearson correlation results of protein z scores versus pathology scores for 96 proteins with correlation coefficients greater than 0.8.)
Zipped Excel file, 48K. - Supplemental file 8 - Table S7 (Overlap of results presented here to prior studies.)
Zipped Excel file, 25K. - Supplemental file 9 - Table S8 (Significance testing for the association of high-abundance immunoglobulin proteins with the HPAI lung samples on days 2 and 7.)
MS Excel file, 22K. - Supplemental file 10 - Legends to supplemental figures and tables
MS Word document, 25K.