Category Term Count % PValue Genes List Total Pop Hits Pop Total Fold Enrichment Bonferroni Benjamini FDR KEGG_PATHWAY hsa05223:Non-small cell lung cancer 13 1.92% 4.5741354904311294E-4 MAPK1, PRKCA, TP53, PIK3R1, AKT1, CASP9, E2F1, ERBB2, PLCG1, SOS1, EGFR, PRKCG, RXRG, 327 52 4214 3.2217125382262997 0.08785942095867716 0.004171328335840219 0.5722762380269586 KEGG_PATHWAY hsa05222:Small cell lung cancer 18 2.65% 2.769803923032281E-4 PTEN, BCL2L1, TP53, PIAS3, PIK3R1, NOS1, PTK2, AKT1, RELA, TRAF1, ITGB1, CASP9, E2F1, APAF1, TRAF3, NOS3, RXRG, MYC, 327 87 4214 2.6662448592217656 0.054158971892669716 0.0029262769463570537 0.34689481953957824 KEGG_PATHWAY hsa04540:Gap junction 19 2.80% 2.754715041277835E-4 PRKG1, GUCY1A2, GNAQ, PRKCA, MAPK1, CDC2, SRC, TUBB, TUBA1A, ITPR1, GUCY1B3, TUBA8, GUCY2C, SOS1, NPR1, EGFR, GNAI2, PRKCG, PRKACA, 327 95 4214 2.57737003058104 0.05387198826642359 0.0030717945842847483 0.3450080668336519 KEGG_PATHWAY hsa05221:Acute myeloid leukemia 13 1.92% 7.870631713848503E-4 RUNX1T1, PML, PIM1, CCNA1, MAPK1, PIK3R1, ZBTB16, RELA, AKT1, STAT3, STAT5A, SOS1, MYC, 327 55 4214 3.045982763413956 0.14637388602815649 0.0060685112392109275 0.9828348883565763 KEGG_PATHWAY hsa04530:Tight junction 24 3.54% 1.5231518992985432E-4 ACTN2, PRKCZ, CTNNB1, PRKCA, PTEN, EPB41L3, CASK, HCLS1, SRC, RAB3B, LLGL1, AKT1, ACTB, ACTN3, MAGI2, PRKCE, CSNK2A1, MYH4, PRKCQ, MLLT4, GNAI2, PRKCG, F11R, MAGI1, 327 132 4214 2.343063664164582 0.03015371101386466 0.0017994193945508608 0.19089934127799468 KEGG_PATHWAY hsa05220:Chronic myeloid leukemia 21 3.10% 4.08601420284372E-7 BCL2L1, MAPK1, TP53, CBLC, SHC3, PIK3R1, AKT1, RELA, ABL1, SHC2, HDAC1, E2F1, STAT5A, CTBP1, SOS1, SMAD3, PTPN11, CRKL, SHC1, CBL, MYC, 327 74 4214 3.65707909744607 8.212552976416543E-5 2.053201477780764E-5 5.125566197361486E-4 KEGG_PATHWAY hsa04520:Adherens junction 20 2.95% 1.8896129465228705E-6 ACP1, ACTN2, CTNNB1, FGFR1, MAPK1, WAS, SRC, PTPN6, ACTB, ACTN3, CREBBP, IQGAP1, ERBB2, CSNK2A1, FYN, RAC1, SMAD3, EGFR, MLLT4, EP300, 327 74 4214 3.4829324737581615 3.7974044144806207E-4 6.330008998278736E-5 0.0023703425807708456 KEGG_PATHWAY hsa05219:Bladder cancer 10 1.47% 0.002831355652887734 E2F1, ERBB2, MMP1, MAPK1, TP53, DAPK1, EGFR, THBS1, MMP9, MYC, 327 40 4214 3.2217125382262997 0.4344234784673927 0.018216224835725714 3.494238028773622 KEGG_PATHWAY hsa04510:Focal adhesion 43 6.34% 6.661798838883796E-10 ACTN2, ZYX, CTNNB1, RAP1A, PRKCA, PTEN, MAPK1, IGF1, CAV3, SRC, VAV1, SHC2, ACTN3, PAK1, ERBB2, COL1A2, SOS1, SPP1, FYN, PPP1CA, EGFR, PRKCG, GSK3B, SHC1, CRKL, THBS1, MAPK10, SHC3, PTK2, JUN, PIK3R1, AKT1, ITGB1, ACTB, ITGB3, THBS2, FLNC, PXN, PAK7, CAV1, RAC1, MAPK8, MYLK, 327 199 4214 2.784595761683033 1.339021488133696E-7 6.6951076682642E-8 8.356694336519865E-7 KEGG_PATHWAY hsa05216:Thyroid cancer 8 1.18% 0.0035622955162754777 CTNNB1, TPM3, MAPK1, TP53, PPARG, RXRG, NTRK1, MYC, 327 27 4214 3.81832597123117 0.5119316275941783 0.021501824596453667 4.3778724161795175 KEGG_PATHWAY hsa04370:VEGF signaling pathway 17 2.51% 7.159138552949953E-5 PRKCA, MAPK1, SRC, MAPKAPK2, PIK3R1, PTK2, AKT1, PLA2G2A, SHC2, CASP9, PXN, HSPB1, PLCG1, RAC1, MAPK14, PRKCG, NOS3, 327 71 4214 3.0855838394280055 0.014287336927041094 0.0010273564513031408 0.08976857066764765 KEGG_PATHWAY hsa05215:Prostate cancer 19 2.80% 8.468110721262606E-5 CTNNB1, FGFR1, PTEN, MAPK1, IGF1, TP53, PIK3R1, AKT1, RELA, CREBBP, CASP9, FOXO1, E2F1, ERBB2, SOS1, EGFR, GSK3B, AR, EP300, 327 87 4214 2.8143695736229746 0.01687757391153588 0.0010632857647163707 0.10617377539098305 KEGG_PATHWAY hsa05214:Glioma 16 2.36% 3.308803779055862E-5 PRKCA, MAPK1, PTEN, IGF1, TP53, SHC3, PIK3R1, AKT1, SHC2, E2F1, PLCG1, SOS1, EGFR, CAMK2A, PRKCG, SHC1, 327 60 4214 3.436493374108053 0.00662873796948682 5.540802431137637E-4 0.0414983729381202 KEGG_PATHWAY hsa05213:Endometrial cancer 13 1.92% 3.098500530753974E-4 CTNNB1, MAPK1, PTEN, TP53, PIK3R1, AKT1, CASP9, APC, ERBB2, SOS1, EGFR, GSK3B, MYC, 327 50 4214 3.350581039755352 0.06038918060663856 0.00310963062063474 0.3879877342091609 KEGG_PATHWAY hsa05212:Pancreatic cancer 16 2.36% 3.575345324155728E-4 MAPK10, BCL2L1, MAPK1, TP53, PIK3R1, AKT1, RELA, STAT3, CASP9, E2F1, STAT1, ERBB2, SMAD3, RAC1, EGFR, MAPK8, 327 73 4214 2.824515102006619 0.06935491274914596 0.003416877290272957 0.4475740832388553 KEGG_PATHWAY hsa05211:Renal cell carcinoma 13 1.92% 0.004632650047484293 RAP1A, MAPK1, JUN, PIK3R1, AKT1, CREBBP, PAK1, PAK7, SOS1, PTPN11, RAC1, EP300, CRKL, 327 67 4214 2.500433611757725 0.6067564816766755 0.026314052743183214 5.658397158126894 KEGG_PATHWAY hsa05210:Colorectal cancer 20 2.95% 1.6998708340129592E-5 CTNNB1, MAPK10, MAPK1, CASP3, TP53, JUN, PIK3R1, AKT1, DVL1, CASP9, APC, FOS, SOS1, FZD1, RAC1, SMAD3, EGFR, GSK3B, MAPK8, MYC, 327 85 4214 3.0322000359776937 0.003410938902560834 3.416185767599611E-4 0.02132142907059764 KEGG_PATHWAY hsa04310:Wnt signaling pathway 27 3.98% 6.939346464098922E-5 CTNNB1, PRKCA, CXXC4, MMP7, DVL1, PORCN, CREBBP, CTBP1, APC, CSNK2A1, FZD1, WNT1, SFRP1, GSK3B, PRKCG, MYC, MAPK10, WNT2, TP53, JUN, SMAD3, RAC1, CAMK2A, MAPK8, EP300, PRKACA, WNT4, 327 151 4214 2.304271219393645 0.013851739799421336 0.0010723915281857233 0.08701369740706788 KEGG_PATHWAY hsa05131:Pathogenic Escherichia coli infection - EPEC 13 1.92% 5.510315741378884E-4 CTNNB1, PRKCA, WAS, HCLS1, TUBB, ITGB1, ABL1, NCK1, TUBA1A, ACTB, KRT18, TUBA8, FYN, 327 53 4214 3.1609255092031616 0.10487139027473158 0.004605523278005341 0.6890308096753062 KEGG_PATHWAY hsa05130:Pathogenic Escherichia coli infection - EHEC 13 1.92% 5.510315741378884E-4 CTNNB1, PRKCA, WAS, HCLS1, TUBB, ITGB1, ABL1, NCK1, TUBA1A, ACTB, KRT18, TUBA8, FYN, 327 53 4214 3.1609255092031616 0.10487139027473158 0.004605523278005341 0.6890308096753062 KEGG_PATHWAY hsa05120:Epithelial cell signaling in Helicobacter pylori infection 18 2.65% 9.834976182060524E-6 MAPK10, CASP3, SRC, JUN, RELA, IL8RA, PTPRZ1, PAK1, CXCL1, PLCG1, CCL5, RAC1, PTPN11, EGFR, HBEGF, MAPK14, F11R, MAPK8, 327 68 4214 3.4112250404749056 0.001974887272536585 2.196247604713264E-4 0.012336491325448673 KEGG_PATHWAY hsa05010:Alzheimer's disease 8 1.18% 0.004441345018119727 LRP1, APP, APBB1, MME, CASP3, C1QA, PSEN2, GSK3B, 327 28 4214 3.6819571865443423 0.5912692510813837 0.02597145260935585 5.430692928074654 KEGG_PATHWAY hsa04012:ErbB signaling pathway 32 4.72% 2.8636764481981953E-14 PRKCA, MAPK1, SRC, CBLC, SHC2, PAK1, ERBB2, BTC, SOS1, EGFR, GSK3B, PRKCG, SHC1, ERBB3, CRKL, MYC, MAPK10, SHC3, JUN, PIK3R1, PTK2, AKT1, NCK1, ABL1, STAT5A, PAK7, PLCG1, CAMK2A, HBEGF, MAPK8, AREG, CBL, 327 85 4214 4.8515200575643105 5.757394561101137E-12 5.757394561101137E-12 3.5926817076870066E-11 KEGG_PATHWAY hsa04010:MAPK signaling pathway 34 5.01% 0.0024872756664161225 FGFR1, RAP1A, PRKCA, FGF8, MAPK1, FGF7, PAK1, SOS1, EGFR, MAPK14, PRKCG, CRKL, FGF13, NTRK1, MYC, MAPK10, CASP3, TP53, MAPKAPK2, JUN, PTPN7, AKT1, PLA2G2A, ARRB2, FGF1, FLNC, FOS, MAP3K8, MOS, RAC1, MAPK8IP1, MAPK8, PRKACA, MAPK8IP2, 327 259 4214 1.6917100586825358 0.3938120479741847 0.01654707425009594 3.075683336098156 KEGG_PATHWAY hsa04920:Adipocytokine signaling pathway 15 2.21% 0.0011545462443651772 MAPK10, PPARGC1A, IRS4, RELA, PPARA, AKT1, STAT3, PTPN11, TNFRSF1B, PRKCQ, SLC2A4, MAPK8, RXRG, IRS1, LEP, 327 73 4214 2.6479829081312056 0.2072107554830186 0.008258490549860276 1.438673451452832 KEGG_PATHWAY hsa04916:Melanogenesis 17 2.51% 0.0030854943164175946 ASIP, CTNNB1, WNT2, GNAQ, PRKCA, MAPK1, DVL1, CREBBP, FZD1, WNT1, CAMK2A, GNAI2, PRKCG, GSK3B, PRKACA, EP300, WNT4, 327 98 4214 2.235474006116208 0.4626701449998887 0.01922354738664067 3.80231525267809 KEGG_PATHWAY hsa04910:Insulin signaling pathway 26 3.83% 2.381762333233158E-5 PRKCZ, MAPK1, CBLC, LIPE, PRKAR2A, SHC2, SOS1, PPP1R3A, PPP1CA, SLC2A4, GSK3B, SHC1, CRKL, MAPK10, PPARGC1A, IRS4, SHC3, PIK3R1, AKT1, INPP5D, FOXO1, FLOT1, MAPK8, PRKACA, IRS1, CBL, 327 134 4214 2.500433611757725 0.0047759579715837 4.351234247207403E-4 0.029873197981111765 KEGG_PATHWAY hsa04810:Regulation of actin cytoskeleton 34 5.01% 7.399797787150015E-5 ACTN2, FGFR1, IQGAP2, FGF8, MAPK1, WAS, VAV1, FGF7, ACTN3, PAK1, ITGB2, APC, SOS1, PPP1CA, EGFR, CRKL, FGF13, MSN, ACTA1, FGD1, PIK3R1, F2, PTK2, ITGB1, ACTB, FGF1, ITGB3, IQGAP1, PXN, PAK7, MOS, RAC1, ARHGEF7, MYLK, 327 214 4214 2.0474434822372745 0.014764070235303905 9.911181101579514E-4 0.09278491247970422 KEGG_PATHWAY hsa04730:Long-term depression 16 2.36% 4.8608294174178404E-4 PRKG1, GUCY1A2, GNAQ, PRKCA, MAPK1, IGF1, RYR1, NOS1, PLA2G2A, ITPR1, GUCY1B3, GUCY2C, NPR1, GNAI2, PRKCG, NOS3, 327 75 4214 2.7491946992864427 0.09310302564931272 0.004239960868027692 0.6080443311538675 KEGG_PATHWAY hsa01510:Neurodegenerative Diseases 10 1.47% 0.002350611175422658 APP, PARK2, APLP1, NGFR, BCL2L1, CASP3, CASP1, PSEN2, EP300, CREBBP, 327 39 4214 3.304320552026974 0.37688801052935617 0.016179035811573983 2.908975327315344 KEGG_PATHWAY hsa04670:Leukocyte transendothelial migration 25 3.69% 6.477605250228188E-6 ACTN2, CTNNB1, RAP1A, PRKCA, VAV1, ACTN3, ITGB2, PTPN11, PRKCG, MAPK14, MSN, PIK3R1, PTK2, ITGB1, ACTB, TXK, NCF2, PXN, PLCG1, CDH5, RAC1, MLLT4, GNAI2, F11R, MMP9, 327 117 4214 2.753600460022478 0.0013011556342250596 1.8598311331363693E-4 0.008125334327113709 KEGG_PATHWAY hsa04664:Fc epsilon RI signaling pathway 19 2.80% 8.14295399556028E-6 LCP2, MAPK10, PRKCA, MAPK1, VAV1, PIK3R1, AKT1, PLA2G2A, SYK, PRKCE, INPP5D, PLCG1, BTK, SOS1, FYN, RAC1, IL4, MAPK14, MAPK8, 327 74 4214 3.3087858500702536 0.0016354016879502886 2.045716245039353E-4 0.010214204952274653 KEGG_PATHWAY hsa04662:B cell receptor signaling pathway 14 2.06% 0.0011475829690270568 FCGR2B, VAV1, JUN, PIK3R1, AKT1, PTPN6, SYK, INPP5D, FOS, BTK, CD72, RAC1, GSK3B, CR2, 327 65 4214 2.775629263702658 0.2060990957541251 0.00851159290488257 1.4300539472454799 KEGG_PATHWAY hsa04660:T cell receptor signaling pathway 24 3.54% 3.899685592379425E-7 CD28, LCP2, ZAP70, TEC, VAV1, CBLC, JUN, PIK3R1, AKT1, NCK1, PTPN6, PAK1, GRAP2, LCK, CD247, PAK7, FOS, PLCG1, SOS1, MAP3K8, FYN, PRKCQ, IL4, CBL, 327 94 4214 3.2902596135077102 7.838062376563926E-5 2.6127557231858667E-5 4.891832923403783E-4 KEGG_PATHWAY hsa04650:Natural killer cell mediated cytotoxicity 28 4.13% 1.1034868233043195E-6 LCP2, PRKCA, MAPK1, VAV1, PTPN6, SHC2, ITGB2, PAK1, CD244, FCGR3A, CD247, SH2D1A, SOS1, FYN, PTPN11, PRKCG, SHC1, ZAP70, CASP3, TYROBP, SHC3, PIK3R1, CD48, SYK, LCK, PLCG1, RAC1, KIR3DL1, 327 129 4214 2.797145769622834 2.217763778331605E-4 4.43592108712032E-5 0.0013842272185815574