Supplemental Data. Pribat et al. (2010). Plant Cell 10.1105/tpc.110.078824 

>TrpH Rat
---------------------------------------------------MIED------------------------------NKENKDHSSERGRVTLIFS---------------------LKNEVGGLIKALKIFQENHVNLLHIESRKSKRRNSEFEIFVDCDINREQ--LNDIFPLLKSHTTVLSVDSPD-QLPEKEDVMETVP--------WFPKKISDLDFCANRVLLYGSELDADHPGFKDNVYRRRRKYFAELAMNYKHGDPIPKIEFTEEEIKTWGTIFRELNKLYPTHACREYLRNLPLLSKYCGYREDNVPQLEDVSNFLKERTGFSIRPVA-GYLSPRDFLSGLAFRVFHCTQYVRHSSDPLYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEE-TVQKLATCYFFTVEFGLCKQ-------------DGQLRVFGAGLLSSISELRHALSGH----AKVKPFDPKVACKQECLITSFQDVYFVSESFEDAKEKMREFAKTVKRPFGVKYNPYTQSIQVLRDSKSITSAMNELRHDLDVVNDALARVSR------WPSV-----------------------------------
>TyrH Rat
MPTPSAPSPQPKGFRRAVSEQDAKQAEAVTSPRFIGRRQSLIEDARKEREAAAAAAAAAVAS----------------------------SEPGNPLEAVVFEERDGNAVLNLLFSLRG--------TKPSSLSRAVKVFETFEAKIHHLETRPAQRP-------LAGSPHLEY-FVRFEVPSGDLAALLSSVRRVS--DDVRSAREDKVP--------WFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQVYRQRRKLIAEIAFQYKHGEPIPHVEYTAEEIATWKEVYVTLKGLYATHACREHLEGFQLLERYCGYREDSIPQLEDVSRFLKERTGFQLRPVA-GLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDE-EIEKLSTVYWFTVEFGLCKQN-------------GELKAYGAGLLSSYGELLHSLSEE----PEVRAFDPDTAAVQPYQDQTYQPVYFVSESFNDAKDKLRNYASRIQRPFSVKFDPYTLAIDVLDSPHTIQRSLEGVQDELHTLAHALSAIS----------------------------------------------
>PheH Rat
----------------------------MAAVVLENGVLSRKLSDFGQETSYIEDN----------------------------------SNQNGAIS--LIFS---------------------LKEEVGALAKVLRLFEENDINLTHIESRPSRLNKDEY-EFFTYLDKRTKPVLGSIIKSLRNDIG-ATVHELS--RDKE---KNTVP--------WFPRTIQELDRFANQILSYGAELDADHPGFKDPVYRARRKQFADIAYNYRHGQPIPRVEYTEEEKQTWGTVFRTLKALYKTHACYEHNHIFPLLEKYCGFREDNIPQLEDVSQFLQTCTGFRLRPVA-GLLSSRDFLGGLAFRVFHCTQYIRHGSKPMYTPEPDICHELLGHVPLFSDRSFAQFSQEIGLASLGAPDE-YIEKLATIYWFTVEFGLCKEG-------------DSIKAYGAGLLSSFGELQYCLSDK----PKLLPLELEKTACQEYSVTEFQPLYYVAESFSDAKEKVRTFAATIPRPFSVRYDPYTQRVEVLDNTQQLKILADSINSEVGILCNALQKIKS---------------------------------------------
>PheH Caenorhabditis
--------------------------------MPPAGQDDLDFLKYAMES-YVADV----------------------------------NADIGKTT--IVFT---------------------LREKAGALAETLKLFQAHDVNLSHIESRPSRLMKDAMRCSLNLLKLKTIVRLKELLSISNKKLKRRFLFKTG--TPKTKQNKDSVP--------WFPQKINDIDQFANRILSYGAELDADHPGFKDMTYRERRKFFADIAFNFKHGDKIPTITYTDEEIATWRTVYNELTVMYPKNACQEFNYIFPLLQQNCGFGPDRIPQLQDVSDFLKDCTGYTIRPVA-GLLSPRDFLAGWAFRVFHSTQYIRHHSAPKYTPEPDICHELLGHVPLFADVEFAQFSQEIGLASLGAPDD-VIEKLATLYWFTIEFGICQQD-------------GEKKAYGAGLLSSFGELQYALSDK----PEVVDFDPAVCCVTKYPITEYQPKYFLAESFASAKNKLKSWAATINRPFQIRYNAYTQRVEILDKVAALQRLARDIRSDISTLEEALGKVNNLKMK-----------------------------------------
>TrpH Caenorhabditis
---------------------------------------------------MIAN-------------------------------------LPDHTRIKHLET---------------------RDSQDG-SSKTMDVLLE--IELFHYG---------KQEAMDLMRLNGLD--VHEVSSTIRPTAIKEQYTEPG------SDDATTGS-------EWFPKSIYDLDICAKRVIMYGAGLDADHPGFKDTEYRQRRMMFAELALNYKHGEPIPRTEYTSSERKTWGIIYRKLRELHKKHACKQFLDNFELLERHCGYSENNIPQLEDICKFLKAKTGFRVRPVA-GYLSARDFLAGLAYRVFFCTQYVRHHADPFYTPEPDTVHELMGHMALFADPDFAQFSQEIGLASLGASEE-DLKKLATLYFFSIEFGLSSDDAADSPVKENGSNHERFKVYGAGLLSSAGELQHAVEGS----ATIIRFDPDRVVEQECLITTFQSAYFYTRNFEEAQQKLRMFTNNMKRPFIVRYNPYTESVEVLNNSRSIMLAVNSLRSDINLLAGALHYIL----------------------------------------------
>TyrH Caenorhabditis
-----------------------------------MRCQKILQQLNDEGIEVIFT-----------------------------------ANDVTPIEFSIILTSTDPTLS-------------------NFVSDILQNMSSAKVQICHVETRGNEAS---HDVLLACKATKNQ-LIHSAELLTQNHVALTKFSIFA--KKLSDEKNQSQI--------WFPRHISELDQCSKCITKYEPTTDPRHPGHGDVAYIARRKFLNDQALEFKFGDEIGYVDYTEEEHATWKAVYEKLGDLHLSHTCAVYRQNLKILQEEKVLTADRIPQIRDVNKFLQKKTGFELRPCS-GLLSARDFLASLAFRVFQTTTYLRHHKSPHHSPEPDLIHELLGHVPMFSDPLLAQMSQDIGLMSLGASDE-HIEKLSTVYWFIVEFGLCKED-------------GKLKAIGAGLLSAYGELMHACSDA----PEHKDFDPAVTAVQKYEDDDYQPLYFVADSIHDALAKLRKYASSMDRPFSVVYDPFTKSIEAIESSADLEKAFSRLSNDLSAITHAADRMKISITM-----------------------------------------
>PheH Drosophila
---------------------------------MYQRQVSFDKPTRVEDSAYIVEG----------------------------------VDIKAARNTCLLFSPRI------------------RRCPAELLANILAILRKHDINLCILSRILAPWFRVSS-CFWRRMENRS---LGKSHRGCEGAML-ATLTSSC--RELQGVMPTAVP--------WFPRRIRDLDRFANQILSYGSELDADHPGFTDPEYAKRRKYFADIGYNYKHGQPLPHVDYTKEEIETWGIIFRNLTKLYKTHACREYNHVFPLLVDNCGFREDNIPQLEDVSNFLRDCTGFTLRPVA-GLLSSRDFLAGLAFRVFHCTQYIRHPSKPMYTPEPDVCHELMGHVPLFADPSFAQFSQEIGLASLGAPDD-YIEKLSTIFWFTVEYGLLAKE-------------GELKAYGAGLLSSYGELEYCLTDK----PQLKDFEPESTGVTKYPITQFQPLYYVADSFETAKEKTIKFANSIPRPFGVRYNAYTQSVEVLDSKPQISNLMDNINSEFQILQNAVAKLRV---------------------------------------------
>TyrH Drosophila
MMAVAAAQKNREMFAIKKSYS--------IENGYPSRRRSLVDDARFETLVVKQTKQTVLEEA------------------------RSKANDYGLTEDEILLANAASESSDAEAAMQSAALVVRLKEGISSLGRILKAIETFHGTVQHVESRQSRVEGVDHDVLIKLDMTRGN-LLQLIRSLRQS----GSFSSMN--LMADNNLNVKAP--------WFPKHASELDNCNHLMTKYEPDLDMNHPGFADKVYRQRRKEIAEIAFAYKYGDPIPFIDYSDVEVKTWRSVFKTVQDLAPKHACAEYRAAFQKLQDEQIFVETRLPQLQEMSDFLRKNTGFSLRPAA-GLLTARDFLASLAFRIFQSTQYVRHVNSPYHTPEPDSIHELLGHMPLLADPSFAQFSQEIGLASLGASDE-EIEKLSTVYWFTVEFGLCKEH-------------GQIKAYGAGLLSSYGELLHAISDK----CEHRAFEPASTAVQPYQDQEYQPIYYVAESFEDAKDKFRRWVSTMSRPFEVRFNPHTERVEVLDSVDKLETLVHQMNTEILHLTNAISKLRRPF-------------------------------------------
>TrpH Drosophila
--------------------MSASGKSLLGLWLYRSGEQEWAVKQGSPLHQLKKDSTTSGSSSHPSLGRNASAPPEPPRLAIGGGGQDNGRQHSPGERISIIFT---------------------LRNQVGNLARALQVFQELGINVLHLELSPLEMATNQADVLVDVECDQRR--LDQVVKMLNREVASVNYTSVNTQGLARAPSLSACSSFDFGDMVWFPRKISDLDKAQN-VLMYGSELDADHPGFKDPVYRKRREQFSAIANNFKHGNPIPRVQYTPEEVKTWGTVFLELHRLYVLHAVPEYMDNWPELEKYCGYREDNVPQLQDVSVYLKRKTGFQLRPVA-GYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANSSFAQFSQEIGLASLGASDA-DIEKLATLYFFTVEFGLCKQA------------DSTFKVYGAGLLSSVAELQHAITAE----NKIKKFDPEVTCQQECIITSYQNAYYYTDSFEEAKEQMRAFAESIQRPFGVRYNPYTMSVEVLSNAKKITAVVSELRGDLSIVCSALRKISATDENLDVDSIANMLHNSLNVRGGASGGGGSPCSPDNSDNSTAEGD
>PheH Pseudomonas aeruginosa
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKTTQYVARQPDDNGFIH------YPETEHQVWNTLITRQLKVIEGRACQEYLDGIEQLG----LPHERIPQLDEINRVLQATTGWRVARVP-ALIPFQTFFELLASQQFPVATFIRTPEELDYLQEPDIFHEIFGHCPLLTNPWFAEFTHTYGKLGLKASKE-ERVFLARLYWMTIEFGLVETD-------------QGKRIYGGGILSSPKETVYSLSDE---PLH-QAFNPLEAMRTPYRIDILQPLYFVLP---DLKRLFQLAQEDIMALVHEAMRLG----------LHAPLFPPKQAA-----------------------------------------------------------
>PheH Chromobacterium violaceum
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNDRADFVVPDITTRKNVGLSHDANDFTLPQPLDRYSAEDHATWATLYQRQCKLLPGRACDEFLEGLERLE----VDADRVPDFNKLNEKLMAATGWKIVAVP-GLIPDDVFFEHLANRRFPVTWWLREPHQLDYLQEPDVFHDLFGHVPLLINPVFADYLEAYGKGGVKAKALGALPMLARLYWYTVEFGLINTP-------------AGMRIYGAGILSSKSESIYCLDSA---SPNRVGFDLMRIMNTRYRIDTFQKTYFVIDSFKQLFDATAPDFAPLYLQLADAQPWGAGDIAPDDLVLNAGDHQGWADTEDV--------------------------------------------------------
>PheH Colwellia psychrerythraea
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAKGTKYVSKVPDEHGFIE------WSTEENLIWQELFTRQIACIKDKACDEYHEGLAKLN----LPTDRIPQLDEVSKVLKVSTGWECYPVP-ALIGFGEFFRLLSEKKFPVATFIRSREEMDYLQEPDIFHEIFGHCPLLTNSSFANYTEAYGKMGLNATKE-QRVFLARLYWFTIEFGLLDTP-------------KGLRIYGGGVLSSPGETDYAMNNT---DVDRKPFDILDVLRTPYRIDIMQPIYYMLTKVSDLDEIRKFEVDDIMELVAQAEALG----------LHEAKFPVKKAS-----------------------------------------------------------
>PheH Chloroflexus aurantiacus
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTTIAPPAMP-------------AYTEEDHLVWATLCARQVPRLDRYACRLFREGFRKLN----LDLQRLPDPVQVSERLAAMTGWTLCDAQNEYLNPTEWFEHIAERRFPVTNYIRRMDELDFTPLPDLFHEYIGHLAFFTDQRFADIAQAFGPLYFAGDER-QRLEIARLWWYSIEFGLIRED-------------GELRAFGAGLLSSIGELDHAFAPD---TPR-VPFDIRRVANTPGAAYSMHETYFILEDLEHVAAILRDYAAMEGLPPVQI-------------------------------------------------------------------------------------
>PheH/TrpH Dictyostelium discoideum
----------------------------------------MESNTNSQGQGIIPQS----------------------------------YHSS------IFFSISK------------------GSDKIGGLLEYLEIIKKHNINITRIESRPSKTEKKDY-DFFLDLEYPTE--NNKEVEKVIKDLE-EKGVKAT--TLQESSNQTYAP--------WFPRKISDLDLFANKVLEMGSDLTSDHPGASDPVYRERRREIAKIASTYKHGDEIPRIDYTEEEIKTWGVVYNRLKELFPTNACHQHAYIFPLLEQNCGYSPDNIPQLQDISNFLQECTGWRIRPVQ-GLLSARDFLNGLAFRVFHATQYIRHPSVPLYTPEPDCCHELLGHVPLLADPDFADFSQEIGLASIGASDE-DIQLLSTCYWFTVEFGLCKEG-------------DTIRAYGAGILSSTGEMEHFLTDK----AKKLPFNPFDACNTEYPITTFQPLYYVAESFQKAKEQMRQFADSFKKPFSIRYNPYTQSIEILDNKDKLLNICNDIRNQSEILADAISKLKA---------------------------------------------
>Pinus taeda
-----------------------------------------------------------------------------------------MAFP---LQKTFLCS-----------------------NGQSFPCS----NGRSTSTLLASDLKFQR---------LNKP------FILRVGSMQIRN-SPKEHPRVS-------SAAVLPP---------VPRSIHDIP-NGDHILGFGANLAEDHPGYHDEEYKRRRSCIADLAKKHKIGEPIPEINYTTEEAHVWAEVLTKLSELYPSHACKEYLESFPLFN----FSPNKIPQLEELSQILQHYTGWKIRPVA-GLLHPRQFLNGLAFKTFHSTQYIRHTSNPMYTPEPDICHEILGHMPMLVHPEFADLAQVIGLASLGASDK-EIWHLTKLYWYTVEFGTIEEN-------------KEVKAFGAGILSSFGELQHMKSSK----PTFQKLDPFAQLPKMSYKDGFQNMYFLCQSFSDTTEKLRSYARTIHSGN----------------------------------------------------------------------------------------
>Physcomitrella patens
-----------------------------------------------------------------------------------------MAMEVGYLRHSTTIT-----------------------NGLCCNCDPKPRGARRVQTRLPGTLCLVKDTFTSSKAKLKKPSQREIFLTSRKRLNQIQAVSTAEKEREA-------DKTSTPP---------IPSSIHDIS-NGDHILGFGADLTEDHPGYHDLEYKRRRSRIADLAKIHKIGEPIPCVDYTSEEIRVWGHVLDTLVDLYPTHACKEYLNCYELFN----FKPNYIPQLQELSEVLERSTGWHIRPVA-GLLHPRDFLNGLAFRTFHSTQYVRHGSNPMYTPEPDICHEVLGHVPILADPEFADLAWAIGQASLGASEK-DIWHLTKLYWYTVEFGTVKEG-------------NEIKAFGAGLLSSFGELKHMRVGTDGFMPEFVELDPFKKMPKMSYKDGYQKRYFLCESFADAAAKLRAYSRSILKPEVQSIKFGDTPIRL---------------------------------------------------------------------------
>Chlamydomonas reinhardtii
--------------------------------------------------------------------------------------------------MLALRQ-----------------------GALLLSAR----GGQTTHDNLQLCAGPSRR-----------PRARWISSAPRPSTLVERHIRPQASTASD-------ATTSTSQ---------RILSIHDVD-NG-QILGFGADLAEDHPGFHDPAYKQRRAWLAEMAKTHRIGTPIPDVEYSPAEVATWDAVLEELSGLLPQHACREYLRCLTLFD----FRKGRVPQLEEMNTVLRSTTGWTVRPVA-GLMHPRHFLAGLAFKHFHSTQYMRHPSKPSYTPEPDVVHELIGHVPLLADPAYARLIQTIGLASLAADDK-QIWHLTKVYWHTVEFGVVREG-------------DQVKAFGAGILSSYGELAHMASGA----AALERLDPFRPQPRMAYKDGFQKRYFVLDSFAEGSELLSSYAASLG--LPESLRGDASVA-----------------------------------------------------------------------------
>Chlorella sp.
-----------------------------------------------------------------------------------------------------MGS-----------------------CRLAADVD----GGQTGHPTARLDAGLSR-----------------------PEGLLRGH------------------------------------SISEVD-NS-KILGFGSDLSEDHPGYLDTFYKQRRADICNLAREHRIGEPIPRIEYTPDEVAVWGTVLPQLKELIPRHACKEFLRCWQLFD----FREDEVPQLEDLSLVLQQQTGFRIRPVA-GLLHPRLFLQGLAYKTFHSTQYMRHVSRPDYTPEPDVVHELIGHVPMLADPAFAELVHAIGIASLGADEK-QIWHLTKIYWYTVEFGVVREG-------------GDVKAFGAGILSSYGELQHMASGA----ARLEPLDVFAPQPKMSYKDGYQQRYFVLDSFAAGADQLKAYCSTLHHAIPGDMRSALGMM-----------------------------------------------------------------------------