Destabilization of Ca2+-free gelsolin may not be responsible for proteolysis in Familial Amyloidosis of Finnish Type -- Data Supplement - Supplemental Data -- Proceedings of the National Academy of Sciences

Supplementary material for Ratnaswamy et al. (January 9, 2001) Proc. Natl. Acad. Sci. USA, 10.1073/pnas.041452598

Supplemental Figure 7 Fig. 7.
Gel filtration analysis of binding of phosphotidylinositol 4,5-bisphosphate to WT gelsolin S2loop. The WT trace is shown in black, and the WT sample incubated with PIP₂ is shown in grey. All the other constructs exhibited similar elution times. Retention volumes of standards of known molecular mass, RNase A (13 kDa) and Albumin (67 kDa), are indicated.