Supplementary material for Basler et al. (2001) Proc. Natl. Acad. Sci. USA 98 (5), 2746-2751. (10.1073/pnas.031575198)

Table 1.

 Scores for histologic lesions and immunohistochemical localization of influenza viral nucleoprotein in the respiratory tracts of mice inoculated with wild-type WSN, 1918 NS A, and 1918 NS B influenza viruses, sampled on 2, 4, and 6 days postinoculation (DPI)

Group

Trachea and primary bronchi

Lung

2 DPI

4 DPI

6 DPI

Mean

2 DPI

4 DPI

6 DPI

Total

Sham control

1* (0)†

1 (0)

1 (0)

1 (0)

1 (0)

1 (0)

1 (0)

1 (0)

WSN NS

3 (3.7)

2.7 (3)

2 (1)

2.6 (2.6)

3.7 (3.7)

4 (4)

3.3 (3.3)

3.7 (3.7)

1918 NS A

1 (1.3)

1 (0)

1 (0)

1 (0.4)

2 (2)

2 (2)

2.7 (2.7)

2.2 (2.2)

1918 NS B

1 (0.3)

1.3 (1)

1 (0.3)

1.1 (0.5)

2.3 (2)

3 (2.3)

2.7 (2)

2.7 (2.1)

*Histologic lesions scores: 1, none; 2, mild; 3, moderate; 4, severe.

†Immunohistochemical localization of influenza nucleoprotein: 0, none; 1, rare; 2, occasional; 3, frequent; 4, common.