Supplemental Data
Files in this Data Supplement:
- Supplementary figure legends (.pdf, 70 KB) - Supplementary materials description
- Supplemental Figure 2 (.jpg, 117 KB) - FIGURE S2. Toca-1 localizes to filopodia in EGF-treated A431 cells.
- Supplemental Figure 1 (.jpg, 239 KB) - FIGURE S1. Toca-1 localization in serum starved A431 cells.
- Supplemental video 2 (.mov, 23.0 MB) - Video 2. Time lapse wound healing migration of Toca-1 knock-down A431 cells. Toca-1 knock-down (shRNA2) cells were serum starved, a wound area generated, and wound healing migration in the presence of EGF (10 ng/ml) was captured every 10 minutes by confocal microscopy for 16 hours at 37 ?C (5% CO2).
- Supplemental video 1 (.avi, 26.6 MB) - Video 1. Time lapse wound healing migration of A431 vector control cells. A431 vector control cells were serum starved, a wound area generated, and wound healing migration in the presence of EGF (10 ng/ml) was captured every 10 minutes by confocal microscopy for 16 hours at 37 ?C (5% CO2).
- Supplemental Figure 3 (.jpg, 729 KB) - FIGURE S3. Toca-1 SH3 domain regulates filopodia localization.
