Supplementary material for Tzung et al. (2001) Proc. Natl. Acad. Sci. USA 98 (6), 3249–3253. (10.1073/pnas.061628798)
Table 2. Candida albicans genes related to genes involved in cellular reproduction in various organisms
Organism | Gene | Ca ORF | Ca Gene | Function |
Dm | DES1 | orf6.4414 | FAD3 | Transmembrane protein; required for initiation of meiosis in fly, homologous to putative fatty acid desaturase in S. pombe |
Dm | pelota | orf6.5174 | DOM34 | Required for spermatogenesis in fly; involved in meiosis, protein translation and pseudohyphal growth in S. cerevisiae |
Sp | RCD1 | orf6.8098 | YNL288 | Involved in sexual development in fission yeast |
Sp | NRD1 | orf6.2205 | YPL184 | RNA-binding protein, negative regulator of sexual differentiation in fission yeast |
Sp | STE20 | orf6.6015 | YER093 | Required for meiosis, amiloride sensitivity, pH regulation in S. pombe |
Sp | MEI4 | orf6.8625 | FKH1 | Meiosis-specific transcription factor with a forkhead domain |
An | palI | orf6.491 | RIM9 | Aspergillus pH signal transduction component |
An | pacC | orf6.8147 | RIM101, PRR2 | Zn finger protein, pH response regulator in Aspergillus |
An | palA | orf6.3059 | RIM20 | Regulator of pH response in Aspergillus |
An | palF | orf6.6250 | RIM8 | Regulator of pH response in Aspergillus |
An | palB | orf6.7408 | RIM13 | Cysteine protease of calpain family |
An | flbA | orf6.2767 | SST2 | Early regulator of asexual sporulation, normal colony development in A. nidulans |
An | flbC | orf6.5156 | YPR013 | Putative Zn finger protein |
An | flbD | orf6.7138 | MYB1 | Myb-like protein; initiates conidiophore development in Aspergillus |
An | abaA | orf6.9129 | TEC1 | Developmental regulator with a TEF-1like DNA-binding domain and a potential leucine zipper domain |
An | dopA | orf6.2672 | DOP1 | Required for correct cell morphology and sexual and asexual cycle development in A. nidulans; leucine zipper-like protein |
An | stuA | orf6.4821 | EFG1 | Transcription factor with a DNA-binding domain related to Swi4, Mbp1, Phd1 in S. cerevisiae; involved in conidiophore development |
Pa | HET-C | orf6.5520 | HET1 | Involved in vegetative incompatibility |
Pa | HET-E-1 | orf6.1133 | YCR072 | Protein with WD-40 domains; controls vegetative incompatibility |
Pa | MOD-D | orf6.6451 | GPA2 | G alpha protein |
Pa | MOD-E | orf6.7645 | HSP90 | Affecting sexual cycle and vegetative incompatibility |
The abbreviations for organisms are Dm for Drosophila melanogaster, Sp for Schizosaccharomyces pombe, An for Aspergillus nidulans, and Pa for Podospora anserina.