Combined X-ray, NMR, and Kinetic Analyses Reveal Uncommon Binding Characteristics of the Hepatitis C Virus NS3-NS4A Protease Inhibitor BI 201335

Supplemental Data

Files in this Data Supplement:

• Supplemental Figure 2 (.pdf, 144 KB) - Analysis of the activity data fit to a two-step binding mechanism
• Supplemental Figure 1 (.pdf, 293 KB) - 2fo-fc electron density of the BI 201335 structure contoured at 1.5��