Saccharomyces cerevisiae Genome-Wide Mutant Screen for Sensitivity to 2,4-Diacetylphloroglucinol, an Antibiotic Produced by Pseudomonas fluorescens
Appl. Environ. Microbiol. Kwak et al. 77: 1770
Supplemental material
Files in this Data Supplement:
- Supplemental file 1 - Supplemental Materials and Methods; collections of fitness profiles using genome-wide deletion strains in S. cerevisiae (Table S1); S. cerevisiae deletion library screened for 2,4-DAPG sensitivity (Fig. S1); Venn diagram illustrating number of yeast mutants found to be sensitive to 2,4-DAPG on agar, in broth, or by both methods (Fig. S2); annotated biosynthesis pathway in 7 of 22 MDR-related mutants with increased sensitivity to 2,4-DAPG on agar and in broth (Fig. S3); biosynthesis pathway of steroids (Fig. S4); distribution of 2,4-DAPG responsive pathways among 209 mutants with increased sensitivity to 2,4-DAPG on agar and in broth (Fig. S5); oxidative phosphorylation in yeast cell (Fig. S6).
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