Fig. 8. 5-hydroxytryptamine (5-HT) response of reticular thalamic neurons in TRPC4^–/– vs. TRPC4^+/+ mice. Top traces show membrane potential plotted vs. time for cells of the reticular thalamic nucleus from wild-type (TRPC4^+/+) and knockout (TRPC4^–/–) mice, respectively. 5-HT was applied with the bathing solution as indicated by the bars. Mean depolarizing response to 5-HT (± SEM) is shown in the bar graph. Differences were not statistically significant (P > 0.01).