The Structure of a High Fidelity DNA Polymerase Bound to a Mismatched Nucleotide Reveals an “Ajar” Intermediate Conformation in the Nucleotide Selection Mechanism

Supplemental Data

Files in this Data Supplement:

• Supplementary figures and legends for supplementary figures and movie (.pdf, 1.9 MB) - Supplementary Figures 1-4
• Supplementary movie (.mov, 1.6 MB) - The transition from the open to the closed conformation in DNA polymerase I as it encounters the correct nucleotide.