Crystal structure of the ectodomain of Methuselah, a Drosophila G protein-coupled receptor associated with extended lifespan -- Data Supplement - Supplemental Figure -- Proceedings of the National Academy of Sciences

Supplementary material for West et al. (March 13, 2001) Proc. Natl. Acad. Sci. USA, 10.1073/pnas.051625298

Supplemental Figure 4 Fig. 4.
Sequence alignment of transmembrane domains of family B GPCRs and Mth homologs. The sequence alignment was performed by using the CLUSTALW program (1). Locations of the predicted transmembrane domains are indicated above the sequences. Relatively conserved residues are color-coded according to chemical properties, and two conserved cysteines are denoted by asterisks. The membrane portion of Mth is related to representative receptors within each group with the following BLAST E values: human CD97: 3 ´ 10^-7; mouse flamingo: 2 ´ 10^-3; rat secretin receptor: 0.65. (Recommendation: View figure file at 150%.)

Reference:

1. Thompson, J. D., Higgins, D. G. & Gibson, T. J. (1994) Nucleic Acids Res. 22, 4673-4680.