>119579650|Homsap|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MSKCRKTPVQQLASPAS ------------------------------------------------------------ ------------------------------------------------------------ -------------FSPDILADIFELF---------------------------------- --AKNFSYGK-------------------PLNNEWQLPD--PSEIF-------------- ----TCDHTEFN--AFLDLKNSLNEVKNLLSDKK-------------------------- ----LDEWHEHTAFTNKAGK-IISHVRKSVN------------------AELCTQAWCKF HEILCSFPLIPQEAF----------------QNGKLNSLHLCEAPGAFIASLNHYLKSHR ---------FPCHWSWV-ANTLNPYHEANDDLMMIMDDR--------------------- --------------------------------------LIANTLHWWYFG--------PD NTGDIMTLKF-LTGLQNFISSMA------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------TVHLVTADGSFDCQGN----------------PGEQEALVSSLHYCEVV TALTTLGNGGSFVLKMF-TMFEHCSINLMYLLNCCFDQVHVFKPATSKAGNSEVYVVCLH YKGR-EAI-HPLLSKMTLNFGT-------------------------------------- -----------EMKRKA--LFPHHVIPDSFLKRHEECCVFFHKYQLETISENIRLFEC-M GKAEQEKL------------------------------------------------NNLR DCAIQYF--------MQKFQLKHLSR------NNWLVKKSSIGCSTNTKWFGQR------ -----------NKYFKTYNERKMLE--A-------------------------------- ---------LSWKDKVAKGYFNSWAEEH----------------------------GVYH PGQSSILEGTASNLECHLWHILEGKKLP-------------------------------- ------------------------------------------------KVKCSPFCNGEI LKTLNEAI---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------E KSLGGAFNLDSKFRPKQQYSCSCHVFSEELIFSELCSLTECLQDEQVVVPSNQIKCLLVG FS-----------------------------------TLRNIK-MHIPLEVRLLESAELT TFSCSLLHDGDPTYQRLFLDCLLHSLRELHTGD-------------VM------------ -----I-LPVLSCFTRFM----AGLIFVL-HSCFRFITFVC----PTSSDPLRTCAVLLC VGYQDLPNPVFRY--LQSVNELLSTLLNSDSPQQ-------------------------- -VLQFVPMEVL------LKGALLDFLWDLNAAIAKRHLHFIIQREREEIINSLQLQN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >50753649|Galgal|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MSTCKKPYVDQTTNLGK ------------------------------------------------------------ ------------------------------------------------------------ -------------FDPEILSEIEKLF---------------------------------- --AKKFSYTK-------------------PLNNEWQLPD--PSDAF-------------- ----TCDHKEFN--SLLDLKNSMNEVKNQLSDKN-------------------------- ----LIEWHQHTSFTNKAGK-IIPHVKKSVN------------------AELCTQAWCKF HEMLCSFPLLPAEAL----------------QEGQLNSVHLCEAPGAFIASLNHYLKSHH ---------IHCDWNWV-ANTLNPYHEANDTLMMIMDDR--------------------- --------------------------------------LIANTLPWWHFG--------PD NTGDVMSLKH-LTGLQNFVSNMA------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------TVHLVTADGSFDCQGN----------------PGEQEALVSPLHYCETV TALMILGAGGSFVLKMF-TLFEHCSTNLLFLLNCCFEEVHVFKPATSKAGNSEAYVICLR YMGR-ESI-HLLLSKMMQNFGT-------------------------------------- -----------DMVSKA--LFPQHVIPESFLKIHEECCMFFHRCQVETICENIYLFEH-M EEAEQTKL------------------------------------------------NKLR DCAVEFF--------MQRFCMKPIAR------NNWLVKKSQAGCSMNAKWFGQR------ -----------NKYFSTYNERKMLE--T-------------------------------- ---------LTWSDKVAKGYLNHVAEEH----------------------------SLNN AGKMCVLEGLSSNLKFNLWYVLEGKRLP-------------------------------- ------------------------------------------------VVKCSPFCDGQV LENLNEAM---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------D ELV-RRPKSKRLLQL----CHSCEVLPGEQILAEVSDLSQSYQEVLNGRCEDKFKCLVVD FP-----------------------------------SLSDTE-GQPSMEIKCLDSATLL TFSFSLLYDGEPKYQQQLLECVLHSLNQLTIGD-------------AL------------ -----I-LPILSCFTRFT----AGLVFVL-HCCFRCITFAC----PMSHEPLKTCSVLLC VGYQGVPNPVIEY--LQHLHKLMSSLLDSDSPKQ-------------------------- -VLQFVPMESL------LQGKLLEFLWELNTAIAKRQLHLLVQAKQQQMTGSISL----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >109129238|Macmul|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MSKCRKTPVQQLASPMS ------------------------------------------------------------ ------------------------------------------------------------ -------------FSPDVLADIFELF---------------------------------- --AKNFSYGK-------------------PLNNEWQLPD--PSEIF-------------- ----TCDHTEFN--AFLDLKNSLNEVKNLLSDKK-------------------------- ----LDEWHEHTAFTNKAGK-IISHVRKSVN------------------AELCTQAWCKF HEILCSFPLIPQEAF----------------QNGKLNSLHLCEAPGAFIASLNHYLKSHR ---------FPCDWSWV-ANTLNPYHEANDDLMMIMDDR--------------------- --------------------------------------LIANTLHWWYFG--------PD NTGDIMTLKF-LTGLQNFISSMA------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------TVHLVTADGSFDCQGN----------------PGEQEALVSSLHYCEVV TALTTLGNGGSFVLKMF-TMFEHCSINLMYLLNCCFDQVHVFKPATSKAGNSEVYVVCLH YKGK-EAI-HPLLPKMILNFGT-------------------------------------- -----------EMKRKA--LFPHHVIPDSFLKRHEECCVFFHKYQLETISENIRLFEC-M GKAEQEKL------------------------------------------------NNLR DCAVQYF--------MQKFQLKHLSR------NNWLVKKSGIGCSTNTKWFGQR------ -----------NKYFKTYNERKMLE--A-------------------------------- ---------LSWKDKVAKGYFNSWAEEH----------------------------GVYH PGQSSILEGAASNLECHLWHILEGKKLP-------------------------------- ------------------------------------------------KVKCSPFCNGEI LKTLNEAI---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------E KSLGGAFNLDSKFRPKQQYSCSCHVFSEELIFSELCSLTKCLQDEQVVEPSNQIKCLLVG FS-----------------------------------TSHNIK-MHIPLEVRLLESAELT TFSCSLLHDGDPTYQHLFLDCLLHSLRELHTGD-------------VM------------ -----I-LPVLSCFTRFM----AGLIFVL-HSCFRFITFFC----PTSSDPLRTCAVLLC VGYQDLPNPVFQY--LQSVNELLSTSLNSDSPQQ-------------------------- -VLQFVPMEVL------LKGALLDFLWDLNAAIAKRHLHFIIQREREEIINSLQLQH--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >224064131|Taegut|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MDKCKQPYVNEKTNLEK ------------------------------------------------------------ ------------------------------------------------------------ -------------FSPEILSEIEKLF---------------------------------- --AKKFTYTK-------------------PVNDEWKLPD--PSNAF-------------- ----TCDHVEFH--SLLALKDSMNEVKNQLSDKN-------------------------- ----LEDWHQHTSFTNKAGK-IISHVKKSVN------------------AELCTQAWCKF HEILCSFSLLPEEAL----------------QDGELNSVHLCEAPGAFIASLNHFLKSHH ---------VPCHWNWV-ANTLNPYHEANDILMMIMDDR--------------------- --------------------------------------LIANTLPWWYFG--------PD NTGDVMTLRH-LTGLQSFVSSMT------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------TVHLVTADGSFDCQGN----------------PGEQEALVSPLHYCETV TALMILGTGGSFVLKMF-TLFEHCSINLLFLLNCSFEEVHVFKPATSKAGNSEAYVVCLR YMGR-ESL-HLLLPKMTQNFGT-------------------------------------- -----------EMVNKA--LFSQHTLPESFLKTHEECCMFFHKCQVETISENIRLFER-M EQAEQMKL------------------------------------------------NKLR DCAVEFF--------MQKFHMKPIGR------NNWLVKKSQAGCSMNAKWFGQR------ -----------NKYFSTYNERKMME--T-------------------------------- ---------LTWNDKVVKGYFNHWAEEH----------------------------SLNN AGNMCILEGPFSNLECSFWYILEGKRLP-------------------------------- ------------------------------------------------RIKCSPFCDVQV LENLNEAV---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------K ELGGERLKSKSMLQS----CQSCEVLPGELILAKVSDLSRCHQEALNESCSDRFKCLVVG FP-----------------------------------TLCNTE-SQPSMEIKPMDAAMLL TFSFSLLYDGEPKYQQHLLECVLHSLAQLAAGD-------------AL------------ -----V-LPVLSCLTRFT----AGLVFVL-HCCFRSIAFAC----PTSREPLSTGAALLC VGYRGLPAPVVEY--LQHLNALMSSLLDTDSPQQ-------------------------- -VLQFVPMEIL------LQSKLLEFLWDLNTAIAKRQLHLIVQAQQQQMTSDIPL----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >73957412|Canlup|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MSKCRKPPLG--SSPET ------------------------------------------------------------ ------------------------------------------------------------ -------------FSPDVLADIFELF---------------------------------- --AKNFSYGK-------------------PLNNEWQLPD--PSEIF-------------- ----TCDHTEFN--TLLDLKNSLNEVKNLLSDKK-------------------------- ----LDEWHEHTAFTNKAGK-IISHVKKSVN------------------AELCTQAWCKF HEILCSFPLIPQEAF----------------QDGKLNSLHLCEAPGAFIASLNHYLKSHR ---------FPCDWSWV-ANTLNPYHEANDNLMMIMDDR--------------------- --------------------------------------LIANTLHWWYFG--------PD NTGDIMTLKY-LTGLQNFVSNMA------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------TIHLITADGSFDCQGN----------------PGEQEALVSSLHYCEVV TALMTLGSGGSFVLKMF-TLFEHCSINLMYLLNCSFDQVHVFKPATSKAGNSEVYVVCLR YKGK-EAI-YPLLSKMVLNFGT-------------------------------------- -----------EMTQKA--LFPHHVIPESFLKRHEECCMFFHKYQLETISENIRLFQC-M GKGEQTKL------------------------------------------------NNLR DCAVQYF--------MQKFQLKPLSR------NNWLVKKSNIGCSTNTKWFGQR------ -----------NRYFKTYNERKMLE--S-------------------------------- ---------LSWKDKVAKGYFNSWAEEH----------------------------AVYH SGQSSVLEGTASNLECHLWHILEGKKLP-------------------------------- ------------------------------------------------NVKCSPFCDGEI LKALNEAI---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------E KSLGGALNLDSKFWPKQQYYCPCHIFTEDLIFSELFSLTTCLQDDQVVEPSNQIKCLLVG FP-----------------------------------TLRDIK-THIPLEVQLLESAELM TFSCSLLHDGDPIYQQLFLDCLLHSLQQLHTGD-------------VM------------ -----I-LPVLSCFTRFM----AGLIFVL-HSCFRFITFSC----PTSSEPLKTCAVLLC VGYQDLPNPVFQY--LQNVNELLSSLLKSDAPQQ-------------------------- -VLQFVPMEVL------LKGALLDFLWDLNAAIAKRHLHVIIQGEREEIIGSLQL----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >197098086|Ponabe|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MSKCRKTPVQQLASPTS ------------------------------------------------------------ ------------------------------------------------------------ -------------FSPDILADIFELF---------------------------------- --AKNFSYSK-------------------PLNNEWQLPD--PSEIF-------------- ----TCDHTEFN--AFLDLKNSLNEVKNLLSDKK-------------------------- ----LDEWHEHTAFTNKAGK-IISHVRKSVN------------------AELCTQAWCKF HEILCSFPLIPQEAF----------------QNGKLNSLHLCEAPGAFIASLNHYLKSHR ---------FPCHWSWV-ANTLNPYHEANDDLMMIMDDR--------------------- --------------------------------------LIANTLHWWYFG--------PD NTGDIMTLKF-LTGLQNFISSMA------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------TVHLVTADGSFDCQGN----------------PGEQEALVSSLHYCEVV TALTTLGNGGSFVLKMF-TMFEHCSINLMYLLNCCLDQVHVFKPATSKAGNSEVYVVCLY YKGR-EAI-HPLLSKMTLNFGT-------------------------------------- -----------EMKRKA--LFPHHVIPDSFLKRHEECCVFFHKYQLETISENIRLFEC-M GKAEQEKL------------------------------------------------NNLR DCAVQYF--------MQKFQLKHLSR------NNWLVKKSSIGCSTNTKWFGQR------ -----------NKYFRTYNERKMLE--A-------------------------------- ---------LSWKDKVAKGYFNSWAEEH----------------------------GVYH PGQSSILEGTASNLECHLWHILEGKKLP-------------------------------- ------------------------------------------------KVKCSPFCNGEI LKTLNEAI---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------E KSLGGAFNLDSKFRPKQQYSCSCHVFSEELIFSELCSLTECLQDEQVVEPSNRIKCLLVG FS-----------------------------------TLHNIK-MHIPLEVRLLESAELT TFSCSLLHDGDPTYQRLFLDCLLHSLRELHTGD-------------VM------------ -----I-LPVLSCFTRFM----AGLIFVL-HSCFRFITFFC----PTSSDPLRTCAVLLC VGYQDLPNPVFQY--LQSVNELLSTLLNSDSPQQ-------------------------- -VLQFVPMEVL------LKGALLDFLWDLNAAIAKRHLHFIIQREREE-INSLQLQN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >195121712|Dromoj|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------MRPKLN------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------IREEVEQLF---------------------------------- --EKKFQYQK------------------PR-NEAWLLP---AQKPL-------------- ----FSEFYQYE--SLQELKQQLNNVKSKLNNYG-------------------------- ----VQEWSTHTNRRDPSGE-ISWRLKNETK------------------AEFVTVAWCKF FECLHRYPLI---------------------KQPELNTLHLCEAPGAFIAALNHYLHSTY TK-------EEINWHWR-STTLNPYYEGNGLNEMITDDR--------------------- --------------------------------------FIFHTLNNWLFH--------RD FTGNLLNVEN-IEHMRDVCAKDLPA----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------GVQLITADGSIDCSAQ----------------PDCQEEIVARLLFAEIL SALHILSPSGNFVIKMF-TLFEACSVSIMFMLNCIFERVHIFKPATSKRGNSEVYVICLN YQKD-TPGLPHLLEAMRSRLAQ-------------------------------------- ---------PNDTMVMP--LFAKSQIPNDFLMQHNIACRLFLKLQEEAIESSIYAYES-K DRYYLRHL------------------------------------------------HQLR GVVSSMY--------YNRYKVRTLPE------ELCIVQQADI-NKALGFSV--------- -----------PVYGGSYTEREHLR--Q-------------------------------- ---------GDVLKQIYCLRREFNQLEKCPTG---------------------------- --LRSYSHVKLH-AKQLQLQPCRGAPIG-------------------------------- ------------------------------------------------QLLSSLFASEPV LLLRLRIL---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------QTFDLDPLWQTAAKCSLCD GN---------------------------------------------NHIMRAFDYAPDS PADESTFYKVQRRFFVALVDSLLEQRPAK------------------------------- -----IVFQAFLFLSHYA----ASVLLLLAEQIYEETQFEN--------------QIITL SG--LSTESKALEQ-LQQLQRLLREDVTD-GLDT-------------------------- -LHSLLPLQQL------HKNPFASALILYNNTVLVSCYRRMLGEEAFPTR-----F---S LEQEQEAATPAINETATI---VC------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >194208779|Equcab|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MSKCRKPPLG--SSPET ------------------------------------------------------------ ------------------------------------------------------------ -------------FSPDVLADVAELF---------------------------------- --AKKFSYGK-------------------SLNNEWQLPD--ASEIF-------------- ----TCDHKEFN--AFLDLKNSLNEVKNLLSDKK-------------------------- ----LDEWHEHTAFTNKAGK-IISHVRKSVN------------------AELCTQAWCKF HEILWSFPLIPQEAF----------------QNGKLNTLHLCEAPGAFIASLNHYLKSHR ---------LPCDWSWV-ANTLNPYHEANDNLMMIMDDR--------------------- --------------------------------------LIANTLRQWYFG--------PD NTGDIMTLQY-LTGLQNFVSNMA------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------TIHLITADGSFDCQGN----------------PGEQEALVSSLHYCEVV TALMTLGNGGSFVLKMF-TLFEHCSINLMYLLNCSFDQVHVFKPATSKAGNSEVYVVCLH YKGR-EAV-HPLLSEMVLNFGP-------------------------------------- -----------EMTRKA--LFSHHVIPESFLKRHEECCVFFHKYQLETISENIRLFEC-M GKGEEAKL------------------------------------------------NNLR DCAVQYF--------MQKFQLKPLAR------NKWLVKKSNIGCSTNTKWFGQR------ -----------NKYFKTYNERKMLE--T-------------------------------- ---------LSWKDKVAKGYFNSWAEEH----------------------------AAYH PGQCSLLEGTASDCECLLWHILEGKKLP-------------------------------- ------------------------------------------------KVKCSPFCDGEI LKTLNEAI---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------E KSLGGALNLDSKFRAKQQYYCSCHIFSEELIFSELFSLTKCLQDDQVVEPSNRVKCLLVG FP-----------------------------------TRSDFQ-MHIPLEVRLLESAELM TFSCSLLHDGDPTYQQLFLDCLLHSLQQLHTGD-------------VL------------ -----I-LPVLSCFTRFM----AGLIFVL-HSCFRFITFSC----PTSSEPLKTCAVLLC VGYQDLPNPVFQY--LQNVSDLLSALLNADAPEQ-------------------------- -VLEFVPMEVL------LKGALLDFLWDLNAAIAKRHLHLIIQREREEIISSLQLGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >126305175|Mondom|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MNNWKKTSGDQAGGLEK ------------------------------------------------------------ ------------------------------------------------------------ -------------FSPDVLADVSELF---------------------------------- --AKKFSYGK-------------------PPNNEWQLPD--SNDVF-------------- ----TCDHTEFN--SLLVLKNSMNEVKNLLSDKN-------------------------- ----LDDWHQHTSFTNKAGK-IIPHVKKIVN------------------AELCTQAWCKF HEVLCSFPLIPQEAF----------------QNGELNSVHLCEAPGAFIASLNHYLRSHN ---------IPCDWNWV-ANTLNPYHEANDNLMMIMDDR--------------------- --------------------------------------LIANTLPWWYFG--------PD NTGDIMTLKH-LTGLQHFISNMS------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------TVHLVTADGSFDCQGN----------------PGEQEALVSPLHYCEVV TALMTLGNGGSFVLKMF-TLFEHCSINLMYLLNCSFEEIHVFKPATSKAGNSEVYVVCLY YLGR-EAI-HPLLTKMMQHFGT-------------------------------------- -----------EIINKA--LFPQHMIPESFLKRHEECCLFFHKYQLETISENIRLFEC-I SEVEQTKL------------------------------------------------NNLR DCAVEYF--------MQKFQMKRLSR------NNWLVKKSNIGCSMNSKWFGQR------ -----------NRYFKTYNERKMLE--A-------------------------------- ---------LSWEDKMTNGYFNHWAEEH----------------------------AISN AGKNTILESVCANLEYHLWYILEGMKLP-------------------------------- ------------------------------------------------KVKCSPFCDGGI LKTLNEAI---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------E KSLGGALNLSSTLRQKPQHCYSCHVLSEELIFSEMLSLAECYQDESAEGQSNKSKCLLVG LL-----------------------------------PPDD-K-IYHSMEVSLLESADLM TFCCSLLHDGKPEYQQVFLDCFLRSLPRLQKGD-------------VL------------ -----I-LPVLSCFTRFM----AGMVFVL-HSCFRFITFSC----PTSSEPLSTCAVLLC VGYRDLPSPVLQY--LQNLKELMSTLLNSDASHQ-------------------------- -VLQFVPMEVV------LNGMLLEFLWDLNTAIAKRQLHLIIQGEQQQKSTFILLGKNDD LMVEQFCCLTILVENNLMKSLMEYSVLLSCFYNMLVLTRTLW------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >149640714|Ornana|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MNKLKKLPAEQTASLEK ------------------------------------------------------------ ------------------------------------------------------------ -------------FSPDVLADISELF---------------------------------- --SKRFSYTK-------------------PPDDAWRLPD--SGDAF-------------- ----TQDHEEFN--SLLVLKDSLNEVKNLLSDKK-------------------------- ----LDEWHQHTSFTNKAGK-IIPHVKKSVN------------------AELCTQAWCKF HEILCSFPLIPQEAF----------------QNGELNSVHLCEAPGAFIASLNHYLKSHH ---------IPCDWNWV-ANTLNPYHEANDNVTMIMDDR--------------------- --------------------------------------LIADTLPRWYFG--------PE NTGDVMTLKH-LSGLQRFVGDMA------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------TVHLVTADGSFDCQGN----------------PGEQEALVSPLHYCEVV TALMILGSGGSLVLKMF-TLFEHCSVNLLYLLNCSFEEVHVFKPGTSKAGNSEVYVVCLN FLGR-EAI-HPLLTKMMQNFEA-------------------------------------- -----------EKVGKA--LFPRHAIPGSFLKCHEECCAFFHRSQLETISENIRLFES-M GEEEQAKL------------------------------------------------NDLR DCAVEVF--------MLKFQVKPLAR------SNWLVKKSNIGCSVNTKWFRQR------ -----------NRYFGTYNERKMLE--T-------------------------------- ---------LSWADKLAKGYFDRWVEEH----------------------------ALIS SGQSCILEGSPSDLQCHSWSVLEGEKLP-------------------------------- ------------------------------------------------RVKCSPFCDGEI LKTLNEAL---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------E KSFGDASSLGRKGPP----CRSCRVLSGDLVFSELLNLTPSLPDSSAEGTGARIKCVVVG LP-----------------------------------SLCDVK-SRVYAEVRLLDSAPLL PFSCSLLHDGEPRYQRQLLDCLLCSLPQLHPGD-------------AL------------ -----I-LPVLSCFTRFS----AGLVFIL-HHCFGSIAFAC----PVSSEPLGSCAVLLC VGYRALPSPVVRY--LRNLSQLTRDLIDSDASRQ-------------------------- -VLQFVPMEAV------LKGALLEFLWDLNTAIAKRQLHLIVQGQQQDKASRLRL----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >119910252|Bostau|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MNKCRKQPLG--SSPET ------------------------------------------------------------ ------------------------------------------------------------ -------------FSPDVLADIFELF---------------------------------- --AKNFSYGK-------------------PLNNEWQLPD--PSEIF-------------- ----TCDHTEFS--AFLDLKNSLNEVKNLLSDKK-------------------------- ----LDEWHEHTAFTNKAGK-IISHVRKSVN------------------AELCTQAWCKF HEILCSFPLIPQEAF----------------QNGKLNSLHLCEAPGAFIASLNHYLKSHR ---------FPCDWNWV-ANTLNPYHEANDNLTMIMDDR--------------------- --------------------------------------LIANTLHCWYFG--------PD NTGDIMTLKY-LTGLQNFINSMG------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------TIHLITADGSFDCQGN----------------PGEQEALVSCLHYCEAV TALMTLGNGGSFVLKMF-TLFEHCSINLMYLLNCSFDQVHIFKPATSKAGNSEVYVVCLY YKGR-ETI-YPILSKMVLNFGS-------------------------------------- -----------EMTKKA--LFPHHMIPESFLRKHEECCTFFHKYQLETISENIRLFEC-M GKREQAKL------------------------------------------------NSLR DYAVQYF--------MQKFQLKPLSR------NNWLVKKSNIGCSTNTKWFGQR------ -----------SRYFKTYNERKMLE--T-------------------------------- ---------LSWKDKVAKGYFNSWAEEH----------------------------ATYH PGQSSLLEGTAFNLECHLWQVLQGKKLP-------------------------------- ------------------------------------------------KVKCSPFCDGEI LKALNESV---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------E KSLGGALNFDLKFRPKQKHCCSCHVFSEELIFSELFSLTKCLQDHQDKEPSTQIKCLLVG FP-----------------------------------ALHNIK-MPIPLEVRLLESAALM TFSCSLLHDGDPTYQQLFLDCVLHSLQQLHTGD-------------VM------------ -----I-LPILSCFTRFM----AGLIFVL-HSCFRFITFSC----PISSEPLKTCAVLLC VGYQDLPNPVFQY--LQNVNELLRDLVNTEAPQQ-------------------------- -VLQFVPMEVL------LKGALLDFLWDLNAAIAKRYLHLIIQGEREEIIGSL------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >157818599|Ratnor|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MSKRRKRPAQQPASPET ------------------------------------------------------------ ------------------------------------------------------------ -------------FSPDALNAVSELF---------------------------------- --AKNFSYCK-------------------PLDHEWQLPA--PAESF-------------- ----TCEHVEFQ--AFLDLKNSLNAVKNLLCDKE-------------------------- ----LDGWHRHTAFTNRAGQ-IIAHVRKAVN------------------AELCTQAWCKF QEILCSFPLIPQEAF----------------QSGRLNSLHLCEAPGAFIASLNHYLKSHR ---------FPCEWSWV-ANSLNPYHEANDNLRMITDDR--------------------- --------------------------------------LIANTLHRWYFG--------PD NTGDIMTLKY-LTGLQDFLSGTS------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------PIHLVTADGSFDCQGN----------------PGEQEALVSPLHYCEAV TALTTLGDGGSFVLKMF-TLFEHCSVNLMYLLNCSFDQVHVFKPATSKAGNSEVYVVCLC YKGR-EAI-RPLLSRMVLNFGT-------------------------------------- -----------EMTKKA--LFPHHVIPKSFLERHRECCTLFHRYQLETISENIRLFEC-M GTGEQEKL------------------------------------------------NNLR NCAVQHF--------MQKFQLKPLSR------NHWLVKKSTLGCSTNTKWFGQR------ -----------NKYFRTYNERKMLE--T-------------------------------- ---------LSWKDKVARGFFDSWAEEH----------------------------VVYH PGQSPLLEGSASSLECHLWCILEGKKLP-------------------------------- ------------------------------------------------KVKCSPFCDSEI LKTLNEAI---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------E KSSGEALSVESKVSPKQQYRC-CQIFSEESVLSELLSLTKCLQEEQGVEPSNPIRCLLVG SP-----------------------------------TVRDLQ-MYTALEVQLLESVELT AFSCSLLHDGDPAYQHLFLNCLLHSLKQLHSGD-------------VM------------ -----I-LPILSCFTRFM----AGLTFVL-HSCFRFITFSC----PTSSEPLRTCAVLLC IGYQNLPDPVFQF--LQNVNELLGTLLHPGAPQQ-------------------------- -VLQFVPMEVL------LQGTLLDFLWDLNAAIAKRHLHLIIQGERDKVISSLEL----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >47087401|Danrer|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MNRGRGVRKRNAPEKASILE T----------------------------------------------------------- ------------------------------------------------------------ -------------CDEEIRAEVAQLF---------------------------------- --NKVRSYVP-------------------PAGEKWTLPD--PNVVL-------------- -----CDPHVSHP-RLQALKHSLNEVKNQLSDKD-------------------------- ----LSVWHQHTCFTNRAGT-VTSHLRSTTN------------------AELCTQAWAKF YEILGTFQLLPDSAL----------------KTGELNSIHLCEAPGAFISALNHFLKTSS ---------LHCDWNWI-ANTLNPYYEANGRGCTITDDR--------------------- --------------------------------------LIVHTLPWWFFG--------SD NTGDIMLQKH-LLELPRFVSNMR------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------SVDLVTADGSFDCQGD----------------PGEQERLVAPLQHCEAI CALLLLGTGGSFVLKMF-TLFEHSSVCLLYLLACCFRSVNIFKPGTSKSGNSELYIVCLD YQAK-EQI-RPLLSKLIRNYGP-------------------------------------- -----------DLASTAS-LFPRRCIPDSFLSQHEEICTFFQALQVNTIQENLRLFVC-M STEQRRRL------------------------------------------------EQLR EYAAEFY--------TKRFSVQYLPR------KSWVCRGGVV------RWVKVCE----- -----------RKQMGSLNQRKEME--L-------------------------------- ---------QGWKQRLAQGNYGPFIEKH----------------------------LVAA EGCEVVLNGPLDECDLGAWFALEGAALP-------------------------------- ------------------------------------------------KVCSSIFCDQEM LDFLNEAL---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------E GNL-RVKTVNWSLKALPT-CSSCSSDSPVSILSEICS------------HPDVTSCLVLG SQ-----------------------------------SWCDDKLTGVRIQPEFLQGPSYC GVQNVTMHDGQPDYQLELLNAVLFALQKQDQGS-------------TL------------ -----V-IPLSSALTRFT----SGLVFTL-HLCFRYITFRC----LSGWPP----AALVC MGFSP-PSALPSL--LDFLQNVMEKMKKVELGRQ-------------------------- -VLQFVPLEEL------LRGELPHFLSSFNTAVIRQQLHMLIQLDQST------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >195029559|Drogri|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------MRPKLS------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------IRDEVEQLF---------------------------------- --EKKFQYQK------------------PK-TGAWQLP---LQEPL-------------- ----FSEFYQYE--SLQNLKEQLNGVKSKLNNYG-------------------------- ----VQEWSTHTNRRDPSGE-ISWRLKNETK------------------AEFVTVAWCKF FECLHRYPLV---------------------KQPQLNTLHLCEAPGAFIAALNHYLHSVY KH-------DEVKWRWR-STTLNPYYEGNALNEMITDDR--------------------- --------------------------------------FIFHTLDNWLFH--------KD LTGNLLNVDN-IEHMTKRCAEDLLD----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------EVHLITADGSIDCSAQ----------------PDCQEELVARLFVAEII SALNILKDGGNFVIKMF-TLFEACSVSLIYLLNCIFRAVHIYKPATSKRGNSEVYVICMD YQKQ-TPGLPRILQAMRVKLAQ-------------------------------------- ---------SSDTMVLP--LFSKAQIPSDFVMQHEIGCRLYLKLQQEAIEGSIYAYET-K DRYYLRHL------------------------------------------------HQLR GVVSSMY--------YNRYKVRPLAD------ELCIVKQEDI-NQALGYSV--------- -----------PVYGGSYTERENLR--Q-------------------------------- ---------GDLLKQIYCLRREFNQLEKCPTG---------------------------- --KSSYKHKQHR-VGSLQMQLSKGAAVQ-------------------------------- ------------------------------------------------ELQSSLFASEPI LLLRLRIL---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------DIFELDPLWQTAPKCLFFD GS---------------------------------------------NN-SKTLDYAPSS EGNESTFHVVQRRFFVTLVESLLAARPAK------------------------------- -----IVFQNFTFLTHYA----ASVLLFLAEIIYEHTEFD---------------QHITL SG--CHKNNDATEQ-LQQLQKFLSDDLGD-ADEA-------------------------- -IHSVLHLREL------QKNAFSNALILHNNSILLECFRRMLGEDSFPRR-----M---S VEQTQ--IVQDIKETTTI---VC------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >31981920|Musmus|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MSKRRKLPARQPACLET ------------------------------------------------------------ ------------------------------------------------------------ -------------FSPDVLNDVSELF---------------------------------- --AKSFSYRK-------------------PLDNEWQLPA--PTESF-------------- ----SCGHLEFR--ALLDLKNSLNEVKNLLSDKK-------------------------- ----LDEWHRHTAFTNKAGK-IISHVKKAVN------------------AELCTQAWCKF QEILCSFPLIPQEAF----------------QSGRLNSLHLCEAPGAFIASLNHYLKSHR ---------FPCEWSWV-ANSLNPYHEANDNLRMITDDR--------------------- --------------------------------------LMANTLHCWYFG--------PD NTGDIMTLKY-LTGLQDFLSGMS------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------PIHLVTADGSFDCQGN----------------PGEQEALVSSLHYCEAV TALITLGDGGSFVLKMF-TLFEHCSVNLMYLLNCSFDQVHVFKPATSKAGNSEVYVVCLR YKGR-EAV-QPLLSRMVLNFGT-------------------------------------- -----------EMTRKA--LFPHHVIPKSFLERHEECCTFFHRYQLETISENIRLFES-M GTGEQERL------------------------------------------------NNLR DCAVQYF--------MQKFQLKPLSR------NHWLVKKSNIGCSMNTKWFGQR------ -----------NKYFKTYNERKMME--T-------------------------------- ---------LSWKDKVAKGYFNSWAEEH----------------------------TVYH PGQNSLLEGTASSLEYQSWQVLEGKKLP-------------------------------- ------------------------------------------------KVKCSPFCDGEI LKTLNEAI---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------E KSLGEALSVDAKVSSKQQYRC-CPVFSEESVLSELLRLTKCLPDEQGAEPSGPVKCLLVG SP-----------------------------------AVCDLQ-MPAPLEIQLVESVELT AFSCSLLHDGDPAYQHLFLDCLLHSLRRLHRGD-------------VM------------ -----V-LPILSCFTRFM----AGLTFVL-HGCFRFITFSC----PTSLEPLRTCAVLLC IGYQNLPDAVFQF--LQNVHDLLSKLLHPSAPRQ-------------------------- -ILQFLPMEAL------LQGTLLDFLWDLNAAIAKRHLHLIIQGERDQAIGSLEL----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >158294159|Anogam|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------MAMEIPPAEDIALEEDAVL RE---------------------------------------------------------- ------------------------------------------------------------ ----------------KIYHEAAAQF---------------------------------- --EKKFQFQP--------------------LPANTPLPP--LDTLY-------------- ----SGPPYTVP--ALEEQKRRLNEVKNRLNDFE-------------------------- ----ISDWHQHTRKRSSLLP-ILNELRYRIR------------------AEFVTQAFAKL YECVSAYELIDG-------------------QQQELYSVHLCEAPGAFVTGLNHYIRLHC A--------PRTKWAWF-ACTLNPHYEGNCPGNMIPDDR--------------------- --------------------------------------FILHTLGSWCFG--------AD GTGDIMVREN-RDAIIKRSQRFP------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------TVHLVTADGSIDCLNV----------------PEEQEERVAKLHLAETV LALSVLSPGQHFVLKMF-TLFEHSSVSLLFLLNHCFDELHVFKPCTSKPGNSEVYIVAKH YRQP-NGI-EQYLDQIYTNLQD-------------------------------------- -------------EARA--IFNRTTIPDTFLEQLRTCTTQFVQWQTDVIESNIRFYRT-S DPLEDQRL------------------------------------------------ALFK QTILEIF--------FTQYHITPIRN------NHRIVHRAKVSEG-LNINQ--------- -----------KESRGTFNERTQLA--AAAD----------------------------- -------ASVTETLRSLCDRLDHLTLTRQLFHPQ----------------------ATLN DPLQEGDPDNGFAPVQHRLFFAIGKPIE-------------------------------- ------------------------------------------------RVKSSKFALITC IRLLNDTV---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------DLVRRVVKEQEIPFPQGEP IT---------------------------------------------VAGNTVTISIASY PSIADNIAQHEKQLFRTIVHTVLELIGQNYVDNLPVA-AYDP--IE-------------- -----LVVQNWLPLTQVS----VGLLYLLKQCVFEEVEQSS-------------PTRLVF RRLRKSALTS-----LVGMHDAVLKAYTRASSLPGPAKS--------------------- -VLAIVPIKVL------LCGSFQYALLNYNNALCLFYCARLLEELQRHLNVD-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >195436461|Drowil|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------MPSIKLN----- ------------------------------------------------------------ ------------------------------------------------------------ -----------------LHQEVEQIF---------------------------------- --GKKFQYQK------------------PKAPQAWQLPPDQKQNPH-------------- ----FGEYYQFP--ALLALKDNLNAVKSKLNDYG-------------------------- ----VEEWSSHTNRRDPSGE-VSWRLKNETK------------------AEFVTVAWCKF FEVLHRYPVV---------------------SQPKLNTVHLCEAPGAFIAALNHYLHSKY QK-------DEIKWNWR-STTLNPYYEGNALTEMITDDR--------------------- --------------------------------------FIFHTLDHWIFH--------ED LTGNLINVSN-IKGMTDRCMKDFAGQ---------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------EVDLITADGSIDCAQQ----------------PESQEEIVQRLFSAEII TALSILKKGGTFVIKMF-TLFEACSVSLLYLLNCVFENVNLYKPATSKRGNSEVYVICLD YQKE-APGLARLLEEMLQKLSN-------------------------------------- ---------PQDAMVMP--LFAKADIPKDFLLQHEIGCRLFMKLQVDAIEGSIYAYES-N DRVYTQHL------------------------------------------------HDLR GLVSSMY--------YNRYKVRPLAE------DLCLVSNKASLNKPLGQFV--------- -----------PIYGGSYTERAKIQ--Q-------------------------------- ---------GDILHQMYCLRREFNQLEKCPNT---------------------------- NAIVSYKHEPLN----GSLRVSWGLPVQ-------------------------------- ------------------------------------------------QLQSSLFASERV LLLRLRLL---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------DTFEMDPIWQINSKCLLN- -----------------------------------------------ATDQSGINYQSPE --ENESFHQGQQKFFANLIEIVLKQKPMT------------------------------- -----IVFDNFLFLSHYA----VSLLLVLGEMIFNEMIINE--------------TSINL NGLKQDLDI------AEQLLSLLKTETS--DGKA-------------------------- -IHSFIDIKYL------QKNQFSQALIQHNNNLLLACYRSMLGEDSFPRPM----ANTAS VESKT--NSSNSNDMVVV------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >195383788|Drovir|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------MRPKLS------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------IREEVEQLF---------------------------------- --EKKFLYQK------------------PK-TSAWLLP---QQEPL-------------- ----FSEFYQYE--SLQELKEQLNRIKSKLNNYG-------------------------- ----VQEWSTHTNRRDPSGE-ISWRLKNETK------------------AEFVTVAWCKI FECLHRFPLV---------------------TQPELNSLHLCEAPGAFVAALNHYLHSVY KQ-------DEIKWCWR-STTLNPYYEGNALNEMITDDR--------------------- --------------------------------------FIFHTLDNWLFH--------KD FTGNLLDVAN-IEHMTERCANDFPA----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------GVQLITADGSIDCSAQ----------------PDCQEEIVARLLFAEIL SALSILSACGNFVIKMF-TLFEACSVSVMYMLNCVFQRVHIYKPATSKRGNSEVYVICLN YQKD-AAGLPRLLEAMRAKLAQ-------------------------------------- ---------PNDAMVMP--LFGKAQIPNDFLLQHNIGCRLFLKLQEEAIESSIYAYES-K DRYYLRHL------------------------------------------------HQLR GVVSSMY--------YNRYKVRPLAE------ELCIVRQQDI-NKALGFSV--------- -----------PVYGGSYTEREHLK--Q-------------------------------- ---------GDLLKQIYCLRREFNQLEKCPTG---------------------------- --TNSYSHVKAHGAPPFKLQLCRGAPVR-------------------------------- ------------------------------------------------ALQSSLFASEPV LLLRLRLL---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------DTFELDPLWQTAPKCLFFD GN---------------------------------------------NSNTQTLDYAPAS DDDESTFHKVQRHFFVMLIESLLAQRPAK------------------------------- -----IVFHKFPFLTHYA----ASVLLLLAEHIFEHTQFEN----------SGTLQTITL TGPQLEANAAALEQ-LQQLQQVLSSDVNE-ARDA-------------------------- -LHSVLPLQQL------QKNQFSNALIQYNNSVLVACFRRMLGEDAFPRR-----L---S RDQAQ--AVPGIKETAAV---VC------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >195153363|Droper|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------MGPKLN------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------LRSELEQLF---------------------------------- --EKKFQYQK------------------PRGDGVWELPR--EEQPL-------------- ----FSEYYQCE--ALQNLKDQLNSVKSKLNDYG-------------------------- ----VQEWSSHTNRRDPSGE-VPWRLKNETK------------------AEFVTVAWCKF FECLHRYPLV---------------------TEPVVNTLHLCEAPGAFIAALNHYLHSTY EK-------DEIKWRWR-STTLNPYYEGNALNEMITDDR--------------------- --------------------------------------FIFHTLDNWLFH--------KD LTGNLINLSN-IEHMVERCAEDFKDNGSG------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------GVDLITADGSIDCAAQ----------------PDCQEEIVVRLFFAETI CALRILKTGGKFVVKMF-TLFEACSVSLLYMLNCIFEQVHIYKPATSKRGNSEVYVICLN YQKD-TPGLARLLEKMQAKLAQ-------------------------------------- ---------PNDAMVMP--LFAKSQIPNDFMMQHEIACRLYMKLQTDAIESSIYAYES-K DRLYFRHL------------------------------------------------HHLR GLVSSMY--------YNRYKVQPLDD------KLCIVDKEVT-SKALGFSV--------- -----------PIYGGSYTEREKLK--D-------------------------------- ---------GDLLKQIYCLRREFNQLEKCPNG---------------------------- --LTSYRYAKDR-VAPLTLRVSRGAPVK-------------------------------- ------------------------------------------------SLQSSLFASEPV LLLRLRIL---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------DTFDLDPIWQASPNCQLD- --------------------------------------------------SQTLSFLPCT EGETETFHSAQRRFFVALLECVRGQRPQK------------------------------- -----IVFHKFLFLTHYS----ASVLLFLVESVYQETHFET-----------NQLQTITL SSPSIREDDAI----VEEVLDLLKSDTGETEEEA-------------------------- -IHSLVQIKEL------QKNKFSNALIQHNNNVLLTCFRRMLGEESFPMP-----IDTGA VEQPS--IVSAIKEAPPIDGVVF------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >125811195|Dropse|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------MGPKLN------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------LRSELEQLF---------------------------------- --EKKFQYQK------------------PRGDGVWELPR--EEQPL-------------- ----FSEYYQCE--ALQNLKDQLNSVKSKLNDYG-------------------------- ----VQEWSSHTNRRDPSGE-VPWRLKNETK------------------AEFVTVAWCKF FECLHRYPLV---------------------TEPVVNTLHLCEAPGAFIAALNHYLHSTY GK-------DEIKWRWR-STTLNPYYEGNALNEMITDDR--------------------- --------------------------------------FIFHTLDNWLFH--------KD LTGNLINLSN-IEHMVERCAEDFKDNGSG------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------GVDLITADGSIDCAAQ----------------PDCQEEIVVRLFFAETI CALRILKTGGKFVVKMF-TLFEACSVSLLYMLNCIFEQVHIYKPATSKRGNSEVYVICLN YQKD-TPGLARLLEKMQAKLAQ-------------------------------------- ---------PNDAMVMP--LFAKSQIPNDFMMQHEIACRLYMKLQTDAIESSIYAYES-K DRLYFRHL------------------------------------------------HHLR GLVSSMY--------YNRYKVQPLDD------KLCIVDKEVT-SKALGFSV--------- -----------PIYGGSYTEREKLK--D-------------------------------- ---------GDLLKQIYCLRREFNQLEKCPNG---------------------------- --LTSYRYAKDR-VAPLTLRVSRGAPVK-------------------------------- ------------------------------------------------SLQSSLFASEPV LLLRLRIL---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------DTFDLDPIWQASPNCQLD- --------------------------------------------------SQTLSFLPCT EGETETFHSAQRRFFVALLECVRGQRPQK------------------------------- -----IVFHKFLFLTHYS----ASVLLFLVESVYQETHFET-----------NQLQTITL SSPSIREDDAI----VEEVLDLLKSDTGETEEEA-------------------------- -IHSLVQIKEL------QKNKFSNALIQHNNNVLLTCFRRMLGEESFPMP-----IDTEA VEHPS--IVSDIKEAPPIDGVVF------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >157114165|Aedaeg|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------MGRKSPSRRRSFYRERRNTVNHYQS E----------------------------------------------------------- ------------------------------------------------------------ ----------------EIAREVADQF---------------------------------- --NKKFRFLR----------------IGDDGDQDPVLPP--LESVFA------------- ----SRTAYQVE--SLQKVKTALNKVKSRLNDFE-------------------------- ----ISDWHQHTRRRSSLQP-ILSELRNRIR------------------AEFVTQAFAKL YECVATYELVPPFSVG---------------KHREFYSVHLCEAPGAFITGLNHYLKLNR G--------DEVKWRWF-ANTLNPYYEGNCLGNMIADDR--------------------- --------------------------------------FILHTMDSWCFG--------AD YTGDIMRKEN-LGEIVRRSKDFP------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------MINLVTADGSIDCLDV----------------PEAQEEHVSKLHLAEAV TALKILTTDGCFILKMF-TFFEHSSVDLLYLLYVCFRELHVFKPATSKPGNSEVYVIAKY FRKP-DGL-DAYLDRMFDNLHS-------------------------------------- --------------ECS--MFDLKDIPSAFVEQVKSCAELFMMHQQEVIEHNIYYYHK-N DTNEEERL------------------------------------------------DIFR KKMCRKF--------FDKYNIKPIPR------SEAILHGVDVSSGVVNINP--------- -----------RDNHGTYNERSLLS--L-------------------------------- -------TNGDERLTILRNKLDAMYDNKPRFMPR----------------------AKLS D-----RSLPSSRSSLEIIQLSCGKSVR-------------------------------- ------------------------------------------------KILSSKFVVFSY IRFLSEVI---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------DTVTSIIPPGEDTPP-LLT LD---------------------------------------------RSSYTLSIDINVY ATMP-SYDLFEKQLFLRLLECITDLPLQEGTDH--------------------------- -----LVVENWLLLTQFC----VGLVFFLKTYVFEHIETVQ-------------GGKLRF SRLKPDGIDS-----LRYLNETIQMEKNGCT----EGKS--------------------- -VLGIVPAYVL------FDGSFYYAVINYNTDLCLHYCSVLLEDK--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >17137638|Dromel|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------MSFRSSPQGKPHPMTDYQS-- ------------------------------------------------------------ ------------------------------------------------------------ ----------------IRPSEVEQLF---------------------------------- --EKKFHYQK------------------PKGNKSWQLPP--PDQAL-------------- ----FSEFYQFE--ALQGLREQLNAVKSKLNDYG-------------------------- ----VQEWSAHTNRRDPSGE-VSWRLKNDTK------------------AEFVTVAWCKL FECLHRYPLV---------------------TKPAVNSMHLCEAPGAFIASLNHYLHSKY EK-------DEIKWRWR-STTLNPYYEGNAINQMISDDR--------------------- --------------------------------------FIVHTLDNWFFH--------KD LTGNLLDVAN-IDHLVERCEVEFQG----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------QVDLVTADGSIDCAAQ----------------PDCQEEIVVRLFFAEVL SALRILSSGGNFLVKMF-TLFEACSVSLLYTLNCIFEEVHIFKPATSKRGNSEVYVICLN YNKD-HPDLPRLLEEIKSKLAQ-------------------------------------- ---------PNDTLVMP--LFAKFQIPHDFLMQHEIACRMYMKLQTDAIEGSIYAYES-N DRHYLRHL------------------------------------------------HHLR SLVANTY--------YSLYKVKPLED------SLCIVDKEAT-SKALGFQV--------- -----------PVYGGSYTERESLK--H-------------------------------- ---------GDLLKQIYCLRREFNQLEKCLNN---------------------------- --RTPYSYVKNR-TAPLNLHISRGAPVQ-------------------------------- ------------------------------------------------SLQSSMFASEPI LILRLRIL---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------DTFELDPVWQSAPKCQLE- --------------------------------------------------SKTLCYLPPT --EDEAFHTAQQRFFIDLLEEVKKLKPDS------------------------------- -----IVFHKFLFLTHYA----ASLLLFLIESVYQDCCFNS-----------NQAQTLTL SKLKD-TANSA----LEQVLELLKDE----QAGA-------------------------- -IHSLLDIKEL------QKNQFSKALIQHNNSIVMTCFRSMLGEESFPMP-----V---A PTSNS--DVGSIQESAAV----F------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >241999224|Ixosca|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------MSSAQDEVERVF---------------------------------- --TKVFAFQK---------------------SSAWQLPAD-PKRWCSE------------ ----ADVAWSLP--DFKRLKTELNATKSLLNDMD-------------------------- ----PAAWRKHTTWTNRAGN-VLNKVRKTAK------------------PALLTQAWCKF YELLHEFQLA---------------------DADPLRSFHLCEAPGAFVTALQHYLLSET G--------SKDTWTWY-ANSLNPYYEGNCSKSTVADDR--------------------- --------------------------------------LMFGTLERWYFG--------QD QTGDVMSPEFKIEEFLEGKE---------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------KFHLVTADGSVDCQDD----------------PAEQESTVAALHGAEIA AAFKLLADGGHFVLKMF-TFFESFSVSLLYLLNCLFEKVTVKKPACSKPGNSEVYVVCRG FQKH-LIT-EVNLTVLTGESSA-------------------------------------- ----------TKKAAFC--FKDVEDLPKDFLGQVDKCVRFFKDLQEEVINENIRWFRIDM NQEACSRL------------------------------------------------QHIK EAVAFTY--------VKKCRCRRVDDP-----TTALLFEDQTTVKSGGWNV--------- ---------------ASFAERSGRK----------------------------------- ------DWWKDRISDLRKILAASSAPQDYLNGSSPF------------------------ --FRTATLDRTEALKASADWIQTGRNYGSFPGL--------------------------- ----------------------------------------------------SKFCSRHL LDLALMLG---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------LQEQADWPKES DK---------------------------------------------------IEPKMGK TDSADSVPDMDMTDKTSGLPQQKAASHL-------------------------------- -----PGLPRQQKSSRIR----PSRTSSAGAWCIASAEVCG------------------- -----------------DTRPLLCGTTVP------------------------------- ---GQLTLHYN---------DRDGIVRRQRRKMASVDSRWVAGGEG-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >194755743|Droana|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------MSLNDGFYPSKGKHRSVPDYQK-- ------------------------------------------------------------ ------------------------------------------------------------ ----------------IKQCDLEQLF---------------------------------- --EKKFRYQK------------------PSGTNKWTLPS--SDQPL-------------- ----FSDFYQFD--ALQGLRTQLNAVKSRLNDYS-------------------------- ----TQEWSAHTNRRDPSGE-VTWRLKNETK------------------AEFVTVAWCKF FECLHRYPLI---------------------KSPVINTLHLCEAPGAFIASLNHYLHSTY KE-------DEIQWRWR-STTLNPYYEGNALNEMVTDDR--------------------- --------------------------------------FIFHTLDNWLFH--------KD LTGNLLNVTN-IESMAARCAADFQG----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------KVDLITADGSIDCAAQ----------------PDCQEEIVVRLFFAEVF SALKILSPGGNFVVKMF-TLFEACSVSLLYMLNCIFHQVHIFKPATSKRGNSEVYVICLD YLKD-TPGLSRILEAIQAKLDQ-------------------------------------- ---------PNDTMVIP--IFARSHIPQDFLMQHEIACRLYTKMQSDAIEGSIYSFES-N DRHYMRHL------------------------------------------------HHLR GLVSDTY--------YHRYKVKVLED------RLCLVNKEAT-NKALGFFV--------- -----------PVYGGSYTERENLK--H-------------------------------- ---------GDLLKQIYCLRREFNQLEKCLSG---------------------------- --ATTSNYVKDG-AKVLKLRVARGAPVK-------------------------------- ------------------------------------------------SLQSSMFASEPI LLLRLRIL---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------DIFDMDPIWQTAPKCHLD- --------------------------------------------------DKVLNYLPPS --ENETYHAAQRKFFIDLLELIDENRPQS------------------------------- -----IVFHKFLFLTHYS----ASVLLFLMQTVYQESNFES-----------KSSQTLTL SKIST-TDSKE----IKEVINLLKDN----QELG-------------------------- -IHSLFEIKEL------QKNHFSSVLIQHNNNVLITCFRGMLGEEAFPRP-----V---A IAPNV---TNAIKEPPAV----F------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >170052241|Culqui|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------MPSRHNRPGRSNRPERSSRSSRDM NWSKLVREKPLGFGRMLRK----------------------------------------- ------------------------------------------------------------ ----------------EADWAVEQQF---------------------------------- --KKKFQFRR-------------------PVEHPPGLPP--LESVF-------------- ----TVPAYTVD--QLQKDKSDLNAVKNRLNDFE-------------------------- ----IGEWHQHTRRRSSLFP-ILQELRHRVR------------------AEFVTQAFAKL YECVAAYELVPG-------------------DATEFYSVHLCEAPGAFITGLNHYLRLTR ---------GDIRWQWF-ANTLNPYYEGNSMGNMITDDR--------------------- --------------------------------------FILETLDRWCFG--------ED CTGDIMKREN-LDAITRRASEFPM------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------VSNLVTADGSIDCLDV----------------PESQEEHVAPLHLAEAV TALKMLTRGGSFILKMF-TMFEHTSVDLLYLLYVCFDELNVFKPCTSKPGNSEVYVIAKG YRRP-DGI-DAYLDRMFANLSS-------------------------------------- --------------TKA--MFDLATLPEDFVEQVHRCAYMFLCFQQDVIEHNIHYYRK-V DSEEEQKL------------------------------------------------EWVK SQMCRKF--------FDVYRIKPIRP------SEAILNGVDIVNGSVNINP--------- -----------RDHTGTYNERSTNS--S-------------------------------- -------LSGDLKRKQLRDKLKNLTLNKPRFNPR----------------------SKLN D-----RPFGSRKTCHELISLSCGKTIE-------------------------------- ------------------------------------------------TLYSSKFATLSY VKFLSEVI---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------DAAATWNVLPKDEPRPP-LFT LT---------------------------------------------RATYTLKIDIQMY AALT-SYNLYEKELFRVLLKSITELPLQEGIDH--------------------------- -----LIVENWLPLTQFS----AGLVFFLKTYVFDGVECTSE-----------PPIQLKF YGLKTDGIAS-----LQHLNEGLQSEDSRES----PAKT--------------------- -VLGIVPIRLL------FDGGFYYALLNYNNRLCLQYCSELLGKGACSVLTSHQNSLNST RDPTRVKIVPKMSLLECTRYRHTQRHFVWLLFIAGIGRRQIKFRNQE------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >198416583|Cioint|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MDHYDPDILTEEAF---------------------------------- --QKRFHYKN-------------------PTDDKWKIPQC---AIF-------------- ----SCEGGVVG--GLSGVKEGLNEVKSSLNHYE-------------------------- ----IQKWNKHTTFVNPSGK-VLNVLRRRIQ------------------PELSTQAWCKF HELLSYGNVIPTNCG----------------AGDTLCSVHLCEAPGGFIASLNHHLKSQR ---------PNVKHKWV-GNTLNPYYEGNPLSSCIVDDR--------------------- --------------------------------------LISRTLKSWCFG--------QD NTGDVFKPEF-MDSLSAHCHNEFDDA---------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------TIGLVTADGSLNCADK----------------PGEQETVVAPLHHVEML DALQLLCSGGTFVMKMF-TLFEVHSASIMYLLCCLFEEVSVIKPATSKAGNSEVYVVCRN YCGL-DGW-KEFHENLRKHFPF-------------------------------------- ----------HNVLNKGFSIFPPSFLPDSFIDQHTACVRLFVTLQESAINRNIFYYNN-I TDDAKSTI------------------------------------------------KQVQ EQVTQRF--------FDVCNLRKIKQ------KLCIVPSGVLQSGGIRSNIKQC------ -----------ARLEGSFSDRVLGK----------------------------------- -----------GVDHASHSSDNGF--------------------------------ESHF HDDPEWIVMRKKHFWWNESSVKLGEKLR-------------------------------- ------------------------------------------------VINSSIFCDTDV IAGYQLSFEQRTIDCESAVLRNDLA----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------------VF HDNSAEMSDDSTHFSDESTNLSLTNLVLEEDLQRIITQHNHTVLEIEPPCGSSVYSEWIS KLIEKTN----------------------PTLAREKLNLKETKPNNFSPKKHEVVFTSVV PSDMLKLCWPELNCRPYMLKLLQILMKNIQKRG-------------SC------------ -----F-IILPSALTRLT----IQSLWIL-SQCFEEFMLQV-------VKIDLKPPAILF VGVKFKANHSY----IHSLDDLTRRELQPGYE---------------------------- -FVELFSVSQMFS----LKSYFFESVRQSNNACLVELSHLFMTSGT-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >193662179|Acypis|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----MFVLKP-----------------------GLALPD--ANAMY-------------- ----TEPEWKLK--EFQELKTLLNRTKQKLNDFD-------------------------- ----LDSWHIHTGKMNPAGQ-VVNHVRRHVR------------------PDFLTQAWCKF YEIACSSDLVSLDEIREE-------------SGTSFTSVHLCEAPGAFIAALNHFLAINH ---------EELRLDWL-AMTLNPYHESNGHPDIVTDDR--------------------- --------------------------------------LMLHTLPNWEFG--------PD YTGDIFQPGY-AEHLYRTVVERFSGK---------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------GAWLVTADGSIDCSDD----------------PGEQETVVSRLHDHETM VALSVLRDNGSLVLKAF-TMFECNSICRMFLLCCLFRSVVLKKPATSKPGNSEVYVVCKG YRGR-SVA-MPYVQAYYANDRQ-------------------------------------- ----------SDPGGAS--MFPLSLVPVEFRQRLLECAEHFAHMQMHTINANVDGLPR-- REALYREM------------------------------------------------KSVQ ASMCQEF--------MLRLGLRSIRY----TQELTFLSVNNFSHKHNWELLRIGR----- -----------KSRGMSFAEKTRIR--H-------------------------------- ---------MDAGQEALVLYREVYRCHELRMA------------------------RRDM ASDVVWYSHMNLIYRLPDVAFRMGKPVT-------------------------------- ------------------------------------------------VVKNSKFCSEAL IHYRHRVL---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------SRFPRVRDGVAVDAECRLSH YR---------------------------------------------SKIDRPRAIVCDL TDVCDEYVFDNTALQHRCLAAIVDALQALSDGD----DL--------------------- -----I-IIGYPLYTQLS----VANVYAV-AKMFNMYGLVK--------PDPRYGHAFVF LEFSSAHHGDWLSVLVNVVWHLVPSDHGNMA----------------------------- -LISWMPFKVL------IEQEVYGDIVAVNNLCIVHEIEPILLSASSAA----------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >195584389|Drosim|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------MSFRSSPQGKPHPMADYNS-- ------------------------------------------------------------ ------------------------------------------------------------ ----------------IRPSELEQLF---------------------------------- --EKKFHYQK------------------PKGNTSWQLPP--PDQAL-------------- ----FSEFYQFE--ALQGLREQLNAVKSKLNDYG-------------------------- ----VQEWSAHTNRRDPSGE-VSWRLKNDTK------------------AEFVTVAWCKL FECLHRYPLV---------------------TKPAVNSMHLCEAPGAFIASLNHYLHSKY EK-------NEIKWRWR-STTLNPYYEGNALNHMISDDR--------------------- --------------------------------------FIFHTLDNWLFH--------KD LTGNLLDVAN-IDHLVERCEVEFQG----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------QVDLVTADGSIDCAAQ----------------PDCQEEIVVRLFFAEVL SALRILSSGGNFLVKMF-TLFEACSVSLLYTLNCIFEEVHIFKPATSKRGNSEVYVICLN YNKD-HPGLPRVLEEIKSKLAQ-------------------------------------- ---------PNDTLVMP--LFARSQIPQDFLMQHEIACRLYMKLQTDAIEGSIYAYES-N DRHYLRHL------------------------------------------------HHLR SLVSNTY--------YSLYKVKPLED------TLCIVDKEAT-SKALGFHV--------- -----------PVYGGSYTERESLK--H-------------------------------- ---------GDLLKQIYCLRREFNQLEKCLNN---------------------------- --RTSYSYVKNR-AAPLNLHVSRGAPVQ-------------------------------- ------------------------------------------------SLQSSMFASEPI LILRLRIL---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------DTFDLDPVWQSAPKCQLG- --------------------------------------------------SKTLSYLPPT --ENEAFHTAQQRFFIDLLEAVKELKPDS------------------------------- -----IVFHKFLFLTHYA----ASLLLFLIESVYQDCSFNR-----------NQAQTLTL SNLKD-TANSA----LEQVLELIKDE----RAGA-------------------------- -IHSLLDIKEL------QKNQFSKALVQHNHSMLMTCFRSMLGEESFPMPV----V---A PTSNT--DVGSVQESAAV----F------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >195335398|Drosec|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------MSFRSSPQGKPHPMADYKS-- ------------------------------------------------------------ ------------------------------------------------------------ ----------------IRPSELEQLF---------------------------------- --EKKFHYQK------------------PKGNTSWQLPP--PDQAL-------------- ----FSEFYQFE--ALQGLREHLNAVKSKLNDYG-------------------------- ----VQEWSAHTNRRDPSGE-VSWRLKNDTK------------------AEFVTVAWCKL FECLHRYPLV---------------------TKPAVHSMHLCEAPGAFIASLNHYLHSKY EK-------NEIKWRWR-STTLNPYYEGNALNQMISDDR--------------------- --------------------------------------FIFHTLDNWLFH--------KD LTGNLLDVAN-IDHLVERCEVEFQG----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------QVDLVTADGSIDCAAQ----------------PDCQEEIVVRLFFAEVL SALRILSSGGNFLVKMF-TLFEACSVSLLYTLNCIFEEVHIFKPATSKRGNSEVYVICLN YNKD-HTGLPRLLEEIKSKLAQ-------------------------------------- ---------PNDALVMP--LFARSQIPQDFLMQHEIACRLYMKLQTDAIEGSIYAYES-N DRHYLRHL------------------------------------------------HHLR SLVSNTY--------YSLYKVKPLED------TLCIVDKEAT-SKALGFHV--------- -----------PVYGGSYTERESLK--H-------------------------------- ---------GDLLKQIYCLRREFNQLEKCLNN---------------------------- --RTSYSYVKNR-AAPLNFHVSRGAPVQ-------------------------------- ------------------------------------------------SLQSSMFASEPI LILRLRIL---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------DTFYLDPVWQSAPKCQLG- --------------------------------------------------SKTLSYLPPT --ENEAFHTAQQRFFIDLLEAVRELKPDS------------------------------- -----IVFHKFLFLTHYA----ASLLLFLIESVYQDCSFNS-----------NQAQTLTL SKLKD-TANSA----LEQVLELIRDE----RAGA-------------------------- -IHSLMDIKEL------QKNQFSKALIQHNHCMLMTCFRSMLGEESFPMPV----V---A PTPNS--DVGSVQESAAV----F------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >156394270|Nemvec|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------MAPKRRNKQRYHPYGESALLSA E----------------------------------------------------------- ------------------------------------------------------------ -------------TLQFIEEETTRLY---------------------------------- --NKRFTLKA--------------------KDKQCELPS--SELLF-------------- ----TTTPETIN--VLQEMKRNLNESKSMLNDID-------------------------- ----IVEWHQHTRRTHKAGL-VVKTLRETMR------------------AEMCTQAFAKL YEVLASYNVVPTEAV----------------SSKKLYGVHLCEAPGAFVAATNHYLRNHH ---------PDLEWVWL-GATLNPYYEGHSPKALLDDDR--------------------- --------------------------------------FIVETLQNWDFG--------AD GTGDLMQLEN-LNHLAEACQG--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------KVHLVTADGSIDCSDE----------------PEEQENAVSQLIFCEAV TALTVLATGGCYVFKMF-TTLEHHMVCLMYLMCCLFEEVHVIKPGTSKGGNSEVYITCCG YTGN---LSPQYHEILYTAYQQ-------------------------------------- -----------DTAEKV--LFPLNSIPREFLYLIKECQEYFINLQNQEISMNIQYFHH-M NRLEKKQL------------------------------------------------FHLR KQAAGYY--------MEKFGVQPIAE------EERVV----------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >195487715|Droyak|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------MSFRSSAQGKPHPMTDYQS-- ------------------------------------------------------------ ------------------------------------------------------------ ----------------IRPSELEQLF---------------------------------- --EKKFHYQK------------------PRGNTSWQLPP--PDQAL-------------- ----FSEFYQFE--ALQSLREQLNAVKSKLNDYG-------------------------- ----VQEWSAHTNRRDPSGE-VSWRLKNDTK------------------AEFVTVAWCKL FECLHRYPLV---------------------TKPAVNSLHLCEAPGAFIASLNHYLHSKY HK-------DEIKWRWR-STTLNPYYEGNALNQMITDDR--------------------- --------------------------------------FIFHTLDNWLFH--------KD LTGNLLDVAN-IDHLVKRCEEEFQG----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------QVDLVTADGSIDCAAQ----------------PDCQEEIVVRLFFAEVL SALRILSSGGSFLVKMF-TLFEACSVSLLYTLNCIFEEVHIFKPATSKRGNSEVYVICLN YLKD-HPGLPRLLEEIKGKLAQ-------------------------------------- ---------PNDTLVMP--LFARSQIPQDFLMQHEIACRLYMKLQTDAIEGSIYAYES-N DRHYLRHL------------------------------------------------HHLR GLVSNNY--------YSLYDVKSLED------SLCIVDKEAT-SKELGFTV--------- -----------PVYGGSYTERETLK--H-------------------------------- ---------GDLLKQIYCLRREFNQLEKCLNT---------------------------- --RTQYSYAKNR-ASPLHLHVSRGAPVQ-------------------------------- ------------------------------------------------CLQSSMFASEPI LLLRLRIL---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------DTFDLDPVWQSAPKCQLE- --------------------------------------------------SKVLIYVPPT --EGEAFHTAQQRFFTDLLEAVKEMKPHS------------------------------- -----IVFHKFLFLTHYA----ASLLLFLIETVYQDCSF-S-----------NQSQALTL SKLKD-TDSSA----LAQVLELLKDE----QAGA-------------------------- -IHSLLDIKEL------QKNQFSNTLIQHNNSMLLTCFRGMLGEESFPMPP----M---A TTSNA--DVSAVQESPAV----F------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >242014593|Pedhum|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------MSFHHKNLTNHRS--- ------------------------------------------------------------ ------------------------------------------------------------ -------------NDVADREEVLQYF---------------------------------- --NKKYTFKP--------------------PEFGWNLPL--ETEMF-------------- ----KEDKWELD--IFIELKEKLNEVKNKLNNYN-------------------------- ----LDDWHKHTRAMNKAGN-LLWTVKKTIA------------------PEFVTQAWLKF YEICCCYDFVSKSAQ----------------EAYYLNSVHLCEAPGAFITSLNHYLKLNH ---------PDLKWDWI-STTLNPYHEENPLSIMINDDR--------------------- --------------------------------------FILHTLDHWKFG--------ED NTGNLMDLNN-MTNLVKEAENMG------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------PVLMVTADGSIDCQNN----------------PGEQESIVSCLVYCEIV CALHILAKGGNFVVKMF-TMYEEQTICLMYLLVCSFEYVHVFKPASSKEGNSENYVICLN YVGP-DSM-KPWLRKLKAYYSE-------------------------------------- -----------ERPNKS--MFRLSDIPKDFFDQLYECTKIFKNYQVEVIERNIYLFESIN NQQSINRT------------------------------------------------KRLR YALADEY--------IKRYNLRPLNSK-----EDEIVGEDK------------------- -----------RWEEGSFNDKIERE--K-------------------------------- ---------MPPVVKVRNLHQNVQKMSI-------------------------------- -RWEYDEEIKWMEFQTFYTPKSN------------------------------------- ------------------------------------------------AVTPAKELSPEL KRIIQKSF---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------SLT DP---------------------------------------------RVRVLNYEDQLWN SLESGQNECCESNVLFDIMDEMEEKMWRGY------------------SL-I-------- -------IQGYPMLTQFT----AGVIYLM-GHLFEKVGFVR---------PSGQHVAVIF REYRCTNHIMNNF--VRELDSQVDKLDRNKEKS--------------------------- -VLSLIPIGELIYKMKIQKAEFERQRSRARVITLRTSLKMARMVITSFILA--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >194880879|Droere|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------MSFRSYAQGKPHPKTDYQS-- ------------------------------------------------------------ ------------------------------------------------------------ ----------------IRPSELEQLF---------------------------------- --EKKFHYQK------------------PRGNTSWQLPP--PDQAL-------------- ----FSEFYQFE--ALQALREQLNAVKSKLNDYG-------------------------- ----VQEWSAHTNRRDPSGE-VSWRLKNDTK------------------AEFVTVAWCKL FECLHRYPLV---------------------TKPAVNTLHLCEAPGAFIASLNHYLHSKY HK-------DEIKWRWR-STTLNPYYEGNALNQMISDDR--------------------- --------------------------------------FIFHTLDNWLFH--------KD LTGNLLDVAN-IDHLVERCEAVFQG----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------QVDLVTADGSIDCAAQ----------------PDCQEEIVVRLFFAEVL SALRILSGGGSFLLKMF-TLFEACSVSLLYTLNCIFEEVHIFKPATSKRGNSEVYVICLN YHKE-HPGLPRLLDEIKGKLAQ-------------------------------------- ---------SNDTLVMP--LFARSQIPQDFLMQHEIACRLYMKLQTDAIEGSIYAYES-N DRHYLRHL------------------------------------------------HHLR GLVSNTY--------YSLYNVKPLED------SLCIVDKEAT-SKALGFTV--------- -----------PVYGGSYTERETLK--Y-------------------------------- ---------GDLLKQIYCLRREFNQLEKCINS---------------------------- --RTPYSYVKNR-TAPLSLHVSRGAPVQ-------------------------------- ------------------------------------------------SLQSSMFASEPI LLLRLRIL---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------DTFDLDPVWQSAPKCQLE- --------------------------------------------------SKTLSYLPPT --ESEGFHTAQQRFFIDLLEAVKELKPHS------------------------------- -----IVFHKFLFLTHYA----ASLLLFLIETVYQDCSFNS-----------NQSQDLTL SKLKE-TDNSA----LKQVLKLLKDE----RAGA-------------------------- -IHSLLEIKEL------QKNQFSNTLIQHNNNVLLTCFRGMLGEESFPMP-----V---A PTSNS--DVSSVQESPAV----F------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >110755491|Apimel|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------METEEYDFKKQQLLHTNKDCMH KN---------------------------------------------------------- ------------------------------------------------------------ ---------------QTQNEYINNLF---------------------------------- --NKRFTIVN---------------------NECYTMP--EPTTMF-------------- ----KDCLWTVD--ELQLIKNELNAIKNCLNNYD-------------------------- ----PDKWQLHTRIRNSAKD-VMTRLKTYIQ------------------PELLTQAWCKF YEIVSSFPLIPMNYIHN--------------NNKCFKSVHLCEAPGAFITSLNHWLKTNV ---------PNIKWDWL-AMTLNPYYEGNPASIMVDDDR--------------------- --------------------------------------FIRHTLNHWCFG--------ED NTGNLMNLKN-LNELIKVAQPHC------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------NIFLITADGSIDCTDV----------------PAEQESVLIHLHFCETI TALQLLATGGSFLLKIF-TIFECNTICLIYLLSCCFSNVSVIKPATSKEGNSETYVVCTN FKGP-TFI-SPYLEKLKEHYEY-------------------------------------- ------------GPKQA--IFSKHDIPYAFMEKIIQCSEFFKSHQCLVIVNNIVTFNS-D ESKMLQDT------------------------------------------------KQIQ CMVADKY--------IKDYNVKKLET------GEIVGNIIILGRTINTNQYK-------- -----------RSLQGSYNERCEKQ--Q-------------------------------- ---------LAPLDRIESFCND-------------------------------------- -------------FNKIEI----------------------------------------- ------------------------------------------------HVSSDEVIKYK- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------FSEFPEDLQI R----------------------------------------------------------- ----------------------SGKIFMM------------------------------- ------------------------------------------------------------ ----VMK----------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >193582624|Acypis|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------MDKTEDSVNNNYTAYEYQGNDGTRE KKHFGNTNGYQN------------------------------------------------ ------------------------------------------------------------ -------------KSSQYDEVVVQLF---------------------------------- --SKQFSLPN---------------------QSKWELPN--PDTML-------------- ----KHCKWELP--DFIHLKKSLNTVKDKLNDFN-------------------------- ----LAEWHRNTKQTNPAGK-VISKVRGIGH------------------PELLTGAWLKF FELLNDYELIPQKSI----------------DNGKLCSVHLCEAPGGFISALNHYIVSQE ---------INIEWDWV-GVSLNPYHEGNGNPDLINDDR--------------------- --------------------------------------FMLYTLNHWFFG--------KD HTGDIFQKNF-YKELYTFVKNRFGE----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------EAHVVTADGSMDCQNN----------------PDEQENVVMRLQIVETM VALMILQKGGSFVVKMF-TMFECNTLCRLYLLSCAFDSVKIKKPVTSKQGNSEVYVVCCG YKGL-QHV-EPWIHTYFLTIDR-------------------------------------- -----------TVSDYC--LFPLKELPKDFLSSMYNCSKYF------------------K IENDTKNL------------------------------------------------TDLQ YWVAKTY--------ANRYKIKPIDP-SQEIVGQNILQSLQYDLPKVSSMR--------- ----------LVMDYSFSEKQRRI-E-----CQASDEAKLLQDEVNMFKEY--------- ----------QWQYDSTVLWFTA------------------------------------- ----EDAKVDSSDFNIQMGKPVS------------------------------------- ------------------------------------------------VIRSSKFCVDTL ID-YSNRARSLFTIPIEDSIKRRDYFWLQIPRQTINGQ---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------LIVCDLTS-- --IYISDCINNNRKQHDSVIAILESFEKLQTSD---------SL---------------- -----L-LIGYPLLTQVN----VGVFFIL-LNMFLKTGVMK--------PDKMGHAFVFC SKVND---QHVDD----LITLLKKLKEHIKDPSITDIVEK--------QEQS-------- -LISFFPIKKL----------------IFQPIYKDIVTVNCLLIINEVKKTVCSYLQQQ- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >91092006|Tricas|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------M------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------SKSKKIRHLF---------------------------------- --DKKIDFAN---------------------NATFELPT----EAF-------------- ----VLPKWSIP--SFQNDKAELNRTKSLLNQFN-------------------------- ----LEEWSRHTKHRDPSSY-ITRFVKQKFH------------------PELVTQAWCKF YECLCSFNVIPKEAI----------------TSSRFTSFHLCEAPGAFISALNHYIASQG ---------LDVQWTWG-ANTLNPDHEGNSPQEMIPDDR--------------------- --------------------------------------LLRHTYKNWYFG--------SD FTGNVTKYCN-HVDLVEKIHE--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------KVWLVTADGSIDCSSD----------------PGNQESHVEFLHYCETL TALALLKPGGSFVLKIF-TMFEHSTICLLYLLNVCFGKVSLFKPGSSKSGNSEVYVICQH FKGP-QVV-EKIWPSLLSPYKS-------------------------------------- ----------GHFVDKS--MFDLNKINPDFLTQLLHISRFFMQKQIEHILDNIRFFRN-A SQNESGKV------------------------------------------------HQIK VYVANRY--------INKYKLKSISR------HLKLVPTLDI------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------SQFFSNEV- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------KKINFVNG VAKFDAKNLVQVNPTLDILDVKLGEKFTQV------------------------------ -------KIGVPLLTNFL----AGVMYIL-ISCFSHVHVHQ-------------NGCIIL CGGDLAKIAPVFAT-VEKRYRSVPDCG--------------------------------- -ILQIVPPGLL------YSNNFFDFVWNYNRLLQFLNKC--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >156548314|Nasvit|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------MEYKYQKKK-QFRTTELEYKNSYRR QSE--------------------------------------------------------- ------------------------------------------------------------ -------------ESPAVLKVVESIF---------------------------------- --KKSFAIVG---------------------NEKYKLPE--PASLF-------------- ----VEDFWQVS--ELQEIKASLNETKSKLNNYC-------------------------- ----FAEWHQHTSHRNKAKD-VEWRVRKEFD------------------PEFVTQAWCKF HEIVSKFSLVPRENIFA--------------NNNKLLSLHLCEAPGAFITCLNHWLKTNM ---------PTVHWNWL-AMTFNPYYEGNSNAKMISDDR--------------------- --------------------------------------FIMHTLNNWFFG--------KD NTGNLMTIEN-LEALIEKAKAKG------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------KVNLITADGSVNCISN----------------PGEQEGIVTSLHFSEVL AAMHILEAGGNLLIKIF-TVFEHQSICLIYFLSCVFKNIMFYKPVTSKEGNSETYMICLN FKGT-EFL-SAYLPKLVQEYGK-------------------------------------- ------------NSVKA--MFKKSDIPECFLQQIIACAKLFKNYQCEVIENNIAAYQS-C RNNSEFEN------------------------------------------------KKIS KLVADKF--------LKDFPLQKLHM------DLQIVGNMRLKKIKNNHWIV-------- -----------ETPAESFNERKEKL--D-------------------------------- ---------LKPAQRLLLFLDP-------------------------------------- -LKSLEPVAKVFVFKPSDLHIDTC-ITLGKPYR--------------------------- ------------------------------------------------RVSSSRFCATQI VDIYNLIF---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------QVVDMESNLQLSL PT---------------------------------------------ETAIAEYEHKLQQ LYNTYKIIKFQYTEIYNNSQTILRIKTTLQTLQNGE------------HL-I-------- -------LLGFLLLTQFN----VGFIYLM-SHMFENVEFAM---------DDNIGCSVIF KNFKKRELILNK---VEQVYKIAENDTKNDNI---------------------------- -ILSVMSVTDI------YDSELYSIIVRLNNWIVKYCVHYISKIYDKDMHQEMQE----- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >115656140|Strpur|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------HLIPDSAL----------------NSGTLHSLHICEAPGAFISSLNHYIKTHK DK-------EIIQWKWL-GTSLNPHCETNTADCTIVDDR--------------------- --------------------------------------LILQTPDCWYFG--------DD NTGDVMSAAN-LAGLERLIQQEMNG----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------TVHLVTADGSVNCQDD----------------PEHQEHRVFPLVFCQSL TALKLLAPEGAFLVKMF-TMYNANTACLMNLLNIAFKEVTVLKPACSKAGNSEVYVMCKS YLGR-DHL-QPQLDTLLQHFGP-------------------------------------- ------------DVGKTP-LFSPAHLPESFVTQLEKCSLKFTNYQVAAIEENLQLYPN-M DPSSRQRI------------------------------------------------DRVR AQCVEMF--------IKRCRLRVARK------HQKLMPNYGSKACSMFKKNMW------- -----------HRLHGSLDDRGEVG--H-------------------------------- ---------RSWKEHLQSILRDLQQQGYKAG-------------------LGGDSQRGSS PKKMRSSVSVSDQLDSSELEGGDSHQTNAGDARLGGGGDGLGLGSGPGPENTG------- ----------------------PTIQAIHCDQPSSAVRCHGDGGHVGRHESAMEVCDHEQ RTLNPVQTSSVQASVGVAGIVGDVAAMDVGSPETTPTISTTSLQECAWSHLAEDASVRVS HSDYSRIAKTVCALCIHSKMELSEDPNVGGEKQHVLDGAVGGQRSTTNETTEGRSSEIFT VQIPWITPGKHDLDSLGSWKIVTGHPVRAVFMSPFCQMPLLDKWRSVR------------ ------------------------------------------------------------ -----------------------------------TNAQVLQQSTGHNVKGHPQCDLSPQ IYEVIEGLLSKRPVPSSGQEESWCCSGVNKQELDLLDQLASTHNAVIKSCRDNNPRGEMF GD---------------------------------------------IQHLLEREADGKR RFKSFFFKLLPSCIARETEPTAGELETKQDFISACLL-AIKE--LQAGG-SL-------- -----H-IWVPGLLTRFS----ACIVYIL-SQAFDLLTLVR---GQRSDVLTAPRVLINC AGFHPNPQIEQN---FQRVYERMKELHQGGSHD--------------------------- -VLRFIPMLSL------FNPDFDKAITRFNENLIREDLLHIVKAELALLDDSDDAGLLDN MSSEIVYC---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >195999168|Triadh|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------MAKSHTVIGNCF---------------------------------- --TKEFTLKS-------------------NHDNLYNLLTLDCDKIF-------------- ----TTASWSLD--QFSKLEKELNEIKSRLNDYD-------------------------- ----IKVWQQHTSYTNLAHD-IVFQLKQQCY------------------PELCTQAWAKF YEILHRCNIDQRLNLQQWSDDLDL-------SQIPLSSLHLCEGPGAFMTSFNHYLKSHY ---------PHLPWQWL-AMTLNPYYEGNKDGSTITDNR--------------------- --------------------------------------LISKTLSHWNFG--------RD NSGNILHRHN-MTFLVESLSQWP------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------SIRLVTADGSIDCSDR----------------PGQQEAIVSPILYCETL TALRILTKDGVYVLKMF-TSFQHRSICLIYLLLNVFQEVKAIKPSCSKSGNSEVYIICIG YIGF-NAIPKQFWDNLCANYGL-------------------------------------- -----------EDRCIS--LFPLDYIPVPIIDKIYTFCQYFSTLQIDAIQRNIRLFDT-L NKSNRKFI------------------------------------------------SKAK KAIAKEY--------ITRYQVYEIQP------EKKIVSSVDVNLSRRDDKFKSI------ -----------GSKAGSFNQR-VGQT-K-------------------------------- ---------RKWSESVNDYNIPELLKIE------------------------------TA PCSSRFPRNRIFREEICNLQWL-------------------------------------- ------------------------------------------------HICNSCFASNEL LLDVMSVR---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------QEQ SRHKQEIKTIDNYQNHSLSPTFYSNSCYKSIADILLSVTKTGNQAKYVVLSGKVQHILSN ICNQSGVSDDQVKVITTSNESAPCSTYFAISSTSELISSFDSCERYIQETFKAVDIVFAD FHPESIKERASQTSHNKLILSEVLLACKVLAMNG------------HL------------ -----I-LTVGDLLSRFQ----CSVVYML-HVFFNKH----------LQQTLSMVSILR- --------------------HDEDGTNEVD------------------------------ -LLCFVPISLLTD----EGSEFYRYIYEINNRSLGFELAVRANKKITAFVKNNSIYCGIP GSSHIRCNHLAAEVFRNLIYDEV------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >25144487|Caeele|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------MLPPKKNDLDGN-- ------------------------------------------------------------ ------------------------------------------------------------ -------------PVNLFSEKEIKDY---------------------------------- --YNDFIFDF---------------------NTCTELPQFLA------------------ ----GNPDYEFS-----KQTNRLTQAAMEIRKIKD------------------------- ----KDLYDQHTDMMHDFAR-NPRILQNY--------------------FICKNKAFLKL CEIFEVFKFDIF-------------------EGSSISSFHLCEGPGYFIEAVHVALMRSR GKNE-----EMSYWKWG-ANTLNPYFENRSCFDKLIDDS--------------------- --------------------------------------HIRPTMDQWYFG--------PS DDGDIEKFTE-EYLIKQKLAG--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------TFDLVTADGSTNTQGK----------------EGEIESIVSSLISAEVE VALKLLRRNGRLILKTY-RFCAKSTRDVMNLLADNFSSIKAIKPMASRPGSSERYIVCDG FGGS-MNMDISML----------------------------------------------- ----------------------------------LQCDEFFVYKQIDRIELHLKTFIEHH RMYLKDNW---------------------------------------------------N SFLKTMK--------DKSFTAE----------SRYFCRELQSMFPS-------------- -----------GSSRSSSPWMRLYG----------------------------------- ---------HNLIRRNNPE-DLKISINR-------------------------------- ------------------------------------------------------------ ------------------------------------------------YILTADIFDPD- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------YQKLDVEQIV AR--------------------------------------------------IMDQEEIL TTSDIQLRTIDSLFV---DPIALKQMLSHNS---------------------KIYYDLLE KVSTKNSADECDWRKNFS---NSNRNYTLKLDTNVTIEHILA---AISEGFDNYMESFTL TNLPQITPPLFLSRISGSMYALLYTIFDKCETRP------------------------RE ICWSGWKGHMTG------RTLIARIRLEIAKCKPGTSIRCFVPMDIFDDFFTRICYRNVV HMTVVSNMCKEN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >157776902|Caebri|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------MSENTKLDAN--- ------------------------------------------------------------ ------------------------------------------------------------ -------------PIEFMSNQEMDNY---------------------------------- --YNNHVFTF---------------------LDHQKMDS--------------------- ----KLDTFEFQ-----NHSKRLEEVALKIRSINN------------------------- ----SKSYDEHTDLMHDYWR-CPNILRNH--------------------FICKNKAFLKM LEILESGFLNHL-------------------PWDNLNSFHLCEGPGYFLDAIYVHRLRTT S--------QHSEWHWG-ANTLNPYFENRSCFEKLIDDS--------------------- --------------------------------------HIRGHERNWYFG--------PS DDGDVAKLTE-DYLIEKGLKG--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------TFDLVTADGSTNTQGK----------------EGQIEEIVGPLIRAEVN AALLLLKPGGSLILKTY-RFCEKQIQDVMFLLADNFSEIRVVKPMASRPGSSERYLICNG FGGH-LPLPMDLL----------------------------------------------- ----------------------------------VLCDEFFIIRQVSRMDLHVKTFENEH GN-QKLSWK------------------------------------------------NRK RFMEQMK--------SYVFEEK-------------IPKNLKKMFPS-------------- ---------------GTSPWLSLYG----------------------------------- ---------HDLIRRNTLE-NQTFAIQN-------------------------------- ------------------------------------------------------------ ------------------------------------------------YINSANLFPKD- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------NFDPEWIM DQ--------------------------------------------------ILGQSKML VTSDIKLESKDSLFI---EPIALQALLSNQN----------------------------- --SS------ADLFEGFS---TVD-----------------------S------------ ------------------------------------------------------------ -----LKNSVP--------STIAHILFALLKEEVGNP----------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >170586496|Brumal|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------MAEIEQLKSIYG--------------------------------- --QVVVSLFS----------------------KHMRLKPLPTDESSN------------- ----TETNEELMS-QLWDLSNCLNELRKTIPSDH-------------------------- ----IDDWRRHTSFTHPLRSFIRKHAKSAYS------------------TEYSTQAFFKF YEILVRFSHLCFPCS---------------------DSFHLCESPGAFISALNVYLILQK NK---------LSWQWNANLSLNPHYEWNSPFDMFLDDE--------------------- --------------------------------------LITSTSSNWLFG--------PD NSGDILKWTN-EYINDIAKKVG-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------KFSLITADGSVYCQDN----------------PAEQERIIFPLLQKEID ISLSLLQTNGTFIVKMY-TAFLNDTVTLLNRLLMCFHEVHVIKPSCSKPGNSEVYLLCAS YTPC-----EQHKEG--------------------------------------------- -----------------------IELFTSYRKILLECSKFFVEHQMQMIWFNITTFGK-I GNDLKKFIE------------------------------------------------QKK IQAAGIY--------EQMMTTSNFEK-----FAAELFSSSFTLLKRPNPWKFS------- ------------KFGGFIEGLRNIT----------------------------------- ------------TEEAHILIEN-------------------------------------- ------------------------------------------------------------ -------------------------------------------------MMICDFMNGNN VAAEQKFN---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ISLCWMCDS CQWAGDFCTNKCNLEEILKIGDAPSETN-------------------------------- -------IKHTLFLEPK-------ILALLKCASLEILDICS------------------- ---------------IVSSSAVNVSLERQEMMLQ-------------------------- -RNSELEISSS------ILRSQFDWISILEEMFFHASNYQVTLLVAN------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >219459199|Braflo|Metazoa ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------MSHKRPHPSPRQPYPKQHGNKPRPRRHH---- ------------------------------------------------------------ ------------------------------------------------------------ -------------FTQDVWDETERLF---------------------------------- --SKTFSFQK-------------------PEDDPWRLPP---AEVFF------------- ----TNQNQPFP--QLLEMKEELNRVKGLLSDKE-------------------------- ----IRSWHEHTNQTNRAGK-VISHLKQTIH------------------PQLCTQAWCKF HEIVSTFPLVSDAAV----------------ENGVFNSVHVCEAPGAFITSLNHFLANWR ---------VDCEWNWV-GNSLNPYYEGNDLEHTIDDDR--------------------- --------------------------------------FIFGTLSNWHFG--------AD NTGDIMSTEN-LRHLKTFVADIQPIHLVTADGSIDCQKNPGEQESIVSQLHYCEVVTADG SIDCQKNPGEQESIVSQLHYCEVVTADGSIDCQKNPGEQESIVSQLHYCEVVTADGSIDC QKNPGEQESIVSQLHYCEVVTADGSIDCQKNPGEQESIVSQLHYCKQVTADGSIDCQKNP GEQESIVSQLHYCEVVTADGSIDCQKN----------------PGEQESIVSQLHYCEVV SALQLLGEGGALVVKKF-TMLEPSSACLMYLLNCAFQEVHVFKPVTSKSGNSEVYVVCVG YSGQ-ETL-AGHMDKLMENFKP-------------------------------------- -----------AGHEND--LFPCETLPETFTSQLVSCCRQFTELQCETIQENLRLFDA-P SEEMAEHI------------------------------------------------RQAR ECCAQEY--------VHRYQLRPIRK------DDRIYTEAATRSQFTSDL----R----- -----------KQLQGSFNERQQLA--Q-------------------------------- ---------LPWAQKILHDGGGGQVPER----------------------------TAIA MLEEP---EPSPDAVHDMVYPVVGRVVR-------------------------------- ------------------------------------------------RIRNSRFCDVHM LGQWNEAL---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------D KA--------------------------QILLPENRPLLTKLQEEFTESSEDEAFLVLKG QQ----------------------------------------------LSQSLLPKVLCL TN-SNVLKMLKPYLSAGLGPKIFSVDSD-------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------PVEMF------LALKEVTPGGDVSPVSPEDRTGVLQDSR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >221123226|Hydmag|Metazoa ------------------------------------------------------------ IKKCAVYRLPKGPEERRKWPRSNIPESKYTVVCSKHWPLKAPYDEENHGNLALVQLLAKY DPLLASHLSMCHKKLIKKIEKLKR-------HDKAGSKDRCALDCVFIEKHLFKAEMVNK ------------------------------------------------------------ ------------------------------------------------------------ -------------HRRAKKKKINEVF---------------------------------- --EHHWGECF---------------------ERHYPLTFLDDNAMT-------------- ----EEEINDFY-ISMMSEKEKLNATKSLLNNID-------------------------- ----IHIWRSHTTQTHKCGL-IVSYLKNYIK------------------AEFVTQAWAKF YTILGTFDLFSE-------------------NLTVANSVHLCEAPGAFISSLNHYLQSKF ---------YNIKFNWI-GTTLNPYYEGNIHGEMIVDDR--------------------- --------------------------------------FLIETLPNWNFG--------KD FSGNIMCASN-MELLIKSVG---------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------SIDIVTADGSIDCSDD----------------PAEQEIVVAPLLLWETV TALNILSIKGNFVLKIF-TTFENFTICLLYFLCKCFESVTLSKPGPSKSGNSEVYVVCKN YQKD-LQS-LSFQKFYQAAIQN-------------------------------------- ------------NLLLV--TKDFYLIPKSFIKCIKSYVFESCRLQVENILFNLDLFKN-P NIDYNCEV------------------------------------------------NEIR HYIAQRF--------LDQFKIHKIEN------FISPLYVMTTNYKGKQSNFKP------- -----------NLKKGSFDDRSISA----------------------------------- -------------HCLNKD--EKALSLD------------------------------LR SENDAF------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----LFKWSWHKSQN-------------------------------------------- ----------------------QNVNYLIETE---------------------------- --------------------TLIIG----------------------------------- --KAFLFINLLDH----LENEFY------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >167518245|Monbre|Choanoflagell ------------------------------------------------------------ ------------------MAGRMPPGGRYGPPPSWQPPNGYNGQVGYHPPSMHPPAFPSH HESHPYWQQPG--------------HHRPNRHESEFDRHAHSRDQYRRRDQYRRRDHYQG RDHYQGRDQYRGRDHGRDSGHDRHRQ---------------------------------- ------------------------------------------------------YSRYEQ SSGPPRRQRSAAPLSPAMQKELDSLF---------------------------------- --NKKYTFPA------------------------ECFAPIEAKQLF-------------- ----VAPEEPIDP-AMQALKDRANGVKGSLDDMDQEARPG----LIFLASDSWFAFTLTG PACPLQLWYRTAKLHNPTKN-VPFTLSRRFR------------------VELPTIAWCKM YEILARYKLLQQH------------------QEMPFATVHVCEAPGAFVAALNHYLRQLY H--------RELKWNWT-GLTLNPYYEDNNPIDMVDSDT--------------------- --------------------------------------LILLTESHWHFG--------HD NTGNMMHAPN-LKGLRDRVLQQEM------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------RVELVTGDGAFDTSAN----------------PAEQEMLTAQLHYCEAV AALACLAPGGTLVLKMF-TFFERCSAALVYLLGGLFETMDICKPATSKAANSETYIVAQR FRGC----DHAILDRLLAHIDP-------------------------------------- ------SHPVDAAGQRLA-LLPSASFTPAFTQHLAQAADEISRFTEDHIQHVIDQ---SR R-TVPANRDEL---------------------------------------------INYQ RAVAEEY--------IQRFGVTEVPA------RLQLSPAVYLDGHSNLST---------- -----------SSRAGTGTRRPEDHGGLQGATLKERQAHLRSTVKRQQAERHKEK----- ------------------------------------------------------------ ---------PDATNADDGTPSQKRVKIQ-------------------------------- -----------------------------------------------------AQGLQLD AEDRPSSERPADPPSRPLSIAERMMQKMGYKPGQGLG-----RDGTGIVQPVQAAP---- --------------REERTGL--------------------------------------- ----------------------------------------------EAARTAFAQRDVKA WQQHAG------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------EAGIVL VS---------------------------------------------PAFDWGAFAGSGR GRAEIDMSTEALS-------QVAAGLHLLRPGGT-------------------------- -----LLVRLAETFTRLT----ASLLHLL-CSTFATCRLVK----PLTSAPFASECFVVC RDYRHVEVALQS---VLSVWQAISTPAPGPDLGVRRE----------------------- LLAFVGMSQL-------LEPTFYRHVVNATERFTIRQISSVQALATLLSEADGPLIRVPV LLEEARQGEDCQELDVDTEDPMER------------------------------------ --------------------------------------LIVFLQQSQMTELQLDGAVPM- ------------------------------------------------------------ --------------------------- >159487565|Chlrei|Viridiplantae ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MRRGSRPERREGGADLR GDHVRDNP---------------------------------------------------- ------------------------------------------------------------ ----------TLLLGAYEEKALALLDDRERYLDT-----------RACVLPAPGEQRGST IIGSKRRGWRR----------------CIHRTQLNHFTGNNADKFFQ------------- -----SAAWSLPE--IVPQRTALNEAKELLDDLD-------------------------- ----NTDWDKYATTANYAEY-VRRDLRKLYG------------------VELATVAWAKM YEMIVRNDLLPRQSPALGPARREGGSGGRV-GERPCVTVHLCEAPGGFVAATNHFLRTHR QE-------WGWAWDWL-AVSLNPYYSGNDQFAMVDDDA--------------------- --------------------------------------FMRATLNHWCFG--------AD DSGDIRRPHN-IRAVWAEVRRRCAAAGVP------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------GAMLVTADGAIDTSMV----------------PAAQELVNASLHFTEIV AALGMLAPGGALVWKGF-TLFEHTSLCTLHLVGCLFESVSVCKPCTSKPCNSEVYVVGRG FRGV----SEEVLELLLAKCGE-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------DVFASG-- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >209879978|Crymur|Alveolata ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------MAKPEFRIYSFPVSESLRL----------------------------------- -----QIPIS-----------------EEPCVLCIKKQVDCYCRSFEENIG--------- ----KSEGYSIE--ELDLLKSQLDGVRSELNSID-------------------------- ----IEIWQDFTRSTNIAQD-IIYKLRNIP-------------------IELPTTGWCKL YEILSFFRWYEMI------------------NENEYRSMHLCECPGGFISALNHYIHNNV LNKRQRQNKGKILWEWK-ANSLNPYYEGHNPYNVLNDDI--------------------- --------------------------------------IYRDTYRVWNMG--------ID DSGDITNCDN-IHYIWSKTSKNTKSCW--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------LADLVTADGSIDTQYN----------------PNEQEQLTSCIQYCEVV CGLGILRKHGSLIVKCF-NIFHHTTISLLALLYYCFNQVHIVKPVMSKGGNSEVYIVALN FQGI-RSILLKSLTLHFKENKS-------------------------------------- -----------RFNDIA--LLPREWVPQEFIKNCVTAGTLFCKWQIDYITRNLIK---FR SFILDNNVQKR------RLCNGGNKEFEYQFCDIVDSDDEKVQKKLKDSLNTCSVSKKER RLFALEY--------IQKLDIRNISP------TQYILPNRDTKSEFRFSTSLSRKGGDR- -----------NRVQGIYIDRQYAF-KLYEDLQKTRSKLYFPLVSYRQVAQKLN------ ---------TDGLLQEKLLYWHELLDNSHNLDQDHVEDYLESELNTIQSSDLNTQTPHSN NNIIKIPIKKEISVDSMFTKTLPLDKYPKGIKPNWLDWSKDD------------------ ----------------TTYQRLMDRVKSQVYMFETDHFFNKVQSFPSFALQMSPYCNDDI IRRYCETIIAVNTPLRNISCGIDTFYGTNLYHNKEGQNVVLPFDFIKFLGTEFN------ ----NSHNTSNSVDPLIDNIISVNDYPLYSQIPANRNIVALFESLCELNKVFGNSTS--- ---------MTEYLAKRGKYLEIYNGTFGGYYEL------FPLSYIMNIIS-SEYHGTIL IVSDLEGHLSFVNNFNEEKSSGK-NIPRKQNDKVRIIDISKE------------------ ------------------------------------------------------------ ---------------------------------------IRFCSQYKQVLNAVTSDYMIQ KF---------------------------------------------DYDLIFIDPFCHI IPTYS-IGQFEIECHNEFVSDLMIALNMIRLGG---------DM---------------- -----V-VVLKSCLTRFT----AGLLLIL-SLVFDKIGIHR---PLSCSSPLLSSMHLLC SGYNDSS-NSIARHFLQYLWDVSFVYNKEKLV---------------------------- INQCVPPTLF-------ASDYFLKWLRDINQEFISQDIDLWEAVIEQQGTSE-------- --DTSKDGLYSWTKKGNITNIQRETLRFILLG--NISND--------------------- ----------------------------IDINNYKNNINEKAEGEMDLLENDVDNFNSTN ISGN--------------------CSEKIQADVCDLLRKSESIVINSFDDNIPNNEDIDP FEENTPDEI-DPF-------------- >239870608|Permar|Alveolata ------------------------------------------------------------ ------------------------------------------------------------ --------------MSEPQQDGGTRGAAVEEGSLGYGEREASGGATSMQVNESEGGSAGS YSLGNDYQKSTGGGSWGNDD---------------------------WSKWKGSSEEILG GVRAVGEGGASSRLVGVIEAMGGTTIGVVVEEEEEVIGGQTIRDLAIMITIIRTSRQPDY DENKPLPHY-FPDRNMLKTDIIKHLY------------------------------EFPR AENPDRDFMRN------------LPHSAEPCEKCKMENKQCICDTANTLGATS------- ----HPRNAGIP-DTVKEAKRKLNETKCQLDGLD-------------------------- ----LESWKPHTRSTLVTSF-VVREVRNYSQ------------------AELCTNAWCKM MEMLEAMPLVPKEPF----------------LLIYIGTMHLCECPGGFISATNHHLRTKH P--------RMKNWQWM-AITLNPYFEGNSLTAMIDDDA--------------------- --------------------------------------FYRETYLKWSTG--------VD DSGNIMAYRN-VRDLVERAQRKQQ------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------VCDIVTADGSVDSQFD----------------ANNQERITTRLHFSELV AALGLLRTGGSLVLKMF-TLFEPSSKAIIWLVRAMFDRCIVCKPEMSKPGNSEVYVVGLG FGFI----RSAVLNRLMALMED-------------------------------------D ALWAGFEAGDDELLERA--IVPDAWMSEDFTKAFAKCSAYFSTQQTDYIERNLRL---FK E-FPFEEKQLI---------------------------------------------NARK RSYPTAF--------IERLDLRRLKE------EDKIVPDPAIPLNQGGNIN--------- -----------STRSLPTAGK--ANKSGTQSSRAEFR-RLYEQTQGRRADLAKEK----- ------------------------------------------------------------ ---------PHAGFVP-------------------------------------------- -----------------------------------------------------TEGGSTV MKGARAEEDEEKVPAIGSNLSKALLEKAGLTG-----------EGLKHGNPIVEVE---- ------------------------------------------------------------ --------------------------------------------------NRRPTDRRGL GHGSVG------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------------ES SG---------------------------------------------GPMVMHAKPAMKM RRELENTLLGKISS-----GDYLKESWYVEGGG--------------------------- ------------MFTECG--------------------------VPLEPYEVKLSKFADS DALDKVVYYR-----TEAAWEQQSGRVEVPKPAEDES----------------------- ---------------------------------ALEEIRKVAGFVEVPLGE--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >156082982|Babbov|Alveolata ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------MSVNKGDKPPALH NE---------------------------------------------------------- ------------------------------------------------------------ -------------KRFVFQSNLNRLL---------------------------------- --SETKRVPP----------------SSTPCAKCEQRKRICICSTVNGAVG--------- ----KAPVYELT--ELADTKIMLSELRDSLNDID-------------------------- ----IEKWSYHTKIMDETSL-VVKQIADITTVVNGRKEPG---------AELVTNAWVKL YEILEFYKVVETLIPRLAE------------DGGTINSFHLSECPGGFIAALNHAIKQRN ---------STANLSWQ-ATSLNPYHEGNSHMECLAEDI--------------------- --------------------------------------LYRDTVTNWLTG--------SD ESGNINKTAN-IEYIWDRVSRASKFNKGRAPV---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------LVDIVTADGSFCCQAD----------------PNNQETLTAPLKLSEVV CALGLMRVGAIFILKMF-TLFEESSLSIFTILKMCFKTVEVYKPHLSKSNGSEVYVVCIG FNGI-TSVLLCALCKIIDEYTA-------------------------------------- -----------SKERRA--IIPKEWVPSSFRAEFVDCAMMFAQIQCRSLRHCMG---QYM Q-ISDENQY-----------------------------------------------FKRK REFAKQF--------LAQFPVNPIPS------DCRLVKYISFSDTVITGKDTSSLYHVP- -----------KRHLPNLESRRVFA-KRYEELQKGRQELYRTSRQKENTSQ--------- -------FIILSEEATCADFGRN------------------------------------T ADLFAFAKTYRPAYPEFSLSP-----LSFDLDPSLIDD---------------------- ------------------------LRMDLKHQKYVKESWFVSAPLHAHHIRMSHFVCNDL LY-DVMHIRLLCGQRIPVVTQMDVFLHDGACGEAMSDINILPNSCTVDLALVAKQ----- ----FLDIKRYKSYTEITSNPSQQFPAISLMKRHNLPGYLIYSFCQN------------- -------------------GTGESLIHFDSSYELQVILDSFVGEGTLKTTLGFNYDQLLS QQEGYKSL---------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------------TTQLQDTTL KN---------------------------------------------SVDFIFCDCRR-S SNFHREVLSEEFKLKHVLVAQLIQAFFCLSPGG---------DL---------------- -----V-IALSTTITRFT----ICIITVL-RVCFQDVYLYR----PESVPPWTQRSYVIC RKYSEGD-NSYIRYYLQCLWDAICLHKKSGRE---------------------------- VLQTLRPAHF---------THLSRQLWEFNTGLLLSHFNDLEIHTKSEPVVRPREFYAMD FLKQHDLVDLLYPSAVIDALGSCRLLS--------------------------------- -------------------------------------LEQQQKCDSSVEPRGSEKRARTE --------------------------------------DTEEHVDTPENSPSQDNSHSPI WSSDEE--------------------- >221502672|Toxgon|Alveolata ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------MKDTEIPSSSSAGPHPSVSASGLL I----------------------------------------------------------- ------------------------------------------------------------ -------------HSNLPDIRLERFY-------------------------------CFR SSLQRLQYAG-----------SQLPPSSSPCRNCEKKRVKCICESVATQVG--------- ----QMPAFSLP--EAEKVRAQLDQVRQRLSSIE-------------------------- ----IAEWKRHTNATDVMKR-VLPTIREKVKDSMGFA------------PELVINSWAKL YEILAQTPALPPLPSCLSSQGFLDSHGARTPAGPCIKSVHLCECPGGFIAATNHFIKTKT K--------GALGHLWR-AVSLSPYHEGGNPSELLDDDV--------------------- --------------------------------------LYRQTEDLWLTG--------YD ETGDIVKKRN-IEFIWNHTSREPRTRDNPAPFG--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------LADLVTADGSFDVQFA----------------PHLQEELTAPLVFAEVV CMLGLLNIRGTGIVKMY-GLLSHQSISILAILSMCFNHVVLAKPSMSRPGNSELYAVCLE FVGI-RSSFLSVLSRLVDSVQD-------------------------------------- ---------VLGKQGKT--IIPKNWLPEEFLQECVEGARFFASHQIQQIDRNLGL---FR Q-LDQAALQRC---------------------------------------------LQRQ REKATEF--------LRRNKIEPINF------QDRIVKDVHFMTDWAKNPFTNSTRRATR -----------RRVQGTLEDRERYH-SLFEALHSARRRQWEAAARRIDGDSGGERRGRTG GRLIPF-VKPEAAVEAVCAFDEAQRRSAE-----------------ETAQNGEGAVERTD SLAEYLELLPRSGDRNDGEEPQGERDSSTPG----------------------VVVSKRL PFWLNHFGRHLKPRRSVSSKSRGDSDTRNSGSDLLSFFAGISGHSQASDECASASAEAPG AEDPDAEREEAEHEEEEGEEEKEQRERWTKELSKGLHRKDYLRSKSRWITPALAIRPFAV RLSRFADDQFMALLMEKRLRLPFVLPYLPSDYLVSEGDHSPPSPVAARCL---------- -------------------SLPSSFTVDLALALLRLCPASPPSVASERAALRGRQQRLDA WRGRLAQRYPSGYLELSSLPETEGDALHSGDREAGERQGAG-VLQDLFLRAEVQLRGSLL LNGVSSRDDGEAEVDSRGGSSSADPPPFFDDFSDWGVDAETDGRQRRCEAAVGKQTGEKG VSHLDLLGEFERGTKSAELIQKFTSKCLSAVGLVYADVTRLEQTDSQHASQRQTSFPLSP SS---------------------------------------------PSSFFELREGCEV ERAFMEIAEAEMRSGVLLVGQLLEAMTVLESNG---------DL---------------- -----I-LRLHSVYMRFT----ASLLLLL-SSTFSNAAFFA----PASLPSWRNQRFFLG YSLRPIEAGETKKI-LGAVWDALVDLQSKRNREEDERQSREGSAGANGRNARNDDAPAWT VSQCLPSKLF-------TSLVPSTWLCQWNDFFLLAQIRDVDRRLKLFAAARRVLSEKDC PSPSLSTAARCSEANEDAEERMQKRRRCDEMAPVMQASKQQTPETEKTSEMRRAAP---- -------------DEKGALEEQIASALFLRTREKREKIVVRFLEKLGVGDFLLPEASPFR QLLSRPASQKTQRHTPDAGAAQSETAKIAEEPQKKASKPWEHLLTEAAESADRAWGNVTF LSLESICQAAVGEGLQRENEASFWRSV >239899696|Permar|Alveolata ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------MTEAGLQML----------------------------------- ----RLPLPT--------------------LPHDSSMMGVLFREAS-------------- -----GPTVSADDGNVVNARAELNKARDEIDSVD-------------------------- ----IAEWRSFSKKLNALDG-LTKDIRARVGFD----------------LPLVNNAWAKF YEVLVAYGPRMFENVG---------------VDKSLRTMHLCECPGGFVAALNVYLAITH PD-------WVEKWQWL-GASLNPYYEANDLNQMVDDDA--------------------- --------------------------------------LYRRTRDRWWTG--------PD GSGNILQPSA-AQDMWRWFGSRATGE---------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------KCHVVTADGSMDVQYD----------------PNKQESLCLPIIFRELL LAIGLLHPGGTFVMKAY-SLLDDATVAALSLAAFMFDTIEVVKPVASKEANSETYWVCLG FRGL-AKEDGAWLRKALAVRDP-------------------------------------- -----------RVELRI--PTNASQSLREFVRAARQVAVTLAEKQTEAIKGKLSRWRE-M GDSDPQPYPKK---------------------------------------------QRTI NSLSGDYVRMLIPPELDLALVKPLLP----ADTAGRLGGVDSRRASRGTVEDRRHDH--- ---------EDDTALGGLRENLAEG----------------------------------- ---------ASFSMQAVTNPTSR-----------------------IPRIPSLTEWLTFT LTTQQLSECPGAYRRITSFTQANNVKIPNSGS---------------------------- ------------------------------------------------VVYSPLVRNATE LKALVRKR---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------LLRFEKCPTVQPRSPGDAVA CS--------------------------------------------LTGDERNRAVIAEL LKEHASVDPDHVSTWDSPLHKAAAIKGKADVSVK-------------------------- -----MLADHSLLVDPFSRQFDPATREELIKSTIDGVEALTIAG----------SSVLL- --LELGAAPVVAVWLGSLLFRL-AQLFNKIKLVQ-----------------------PCS GMNLRPPVATLVC-------DLDDSVLRCSSWVVCMGRLSGGRAKSSLRTIRDAI----- --ASRDVSTPMAPMTCTL------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >66362924|Crypar|Alveolata ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------MVKPEFRIYSFPSCETIKL---------------------------------- -----RIPFS-----------------VVPCSNCASKGYECYCNAIKEGLG--------- ----KHEGYSIK--ELESLKSQLDSVRNELDLID-------------------------- ----INVWQSFTRTTNIAQD-VIYKLREIP-------------------VELATTGWCKL YEILHYFRWHEYI------------------NEAEYHSMHLCECPGGFISALNHYIHLNV INKRQRLGSSKLHWEWK-ANSLNPYFEGNNPNAILTDDI--------------------- --------------------------------------IYRDTYRAWNMG--------AD DSGDITKVCN-IDYIWQKTSKNTKNCW--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------LADLVTADGSLDIQYN----------------PNEQEKLTSSIQYCETV CALGILRKHGSFIIKCF-NILHHTTISIIALLCYCFQNVHIVKPIMSKGGSGEIYIVAMN FQGI-RSVMLKALISHFQGNKD-------------------------------------- -----------NFHDFS--LFPKEWLPDEFIEQCVTAATLFSKWQIDNISYNLLK---YK SFVVNDLKYKRMKFSDLDLSNSTSHD-NHEESNIMN-EQSKGELIKENYLFDSGVSKREK RIFALEY--------LQNLGISNIPT------SQYILPNLQHRKEYLNSTSLSRRGGDR- -----------NRVQGIFIDRKYAF-QQYTKLQETRNKCYFPSISFVKLASSNN------ ---------IDSFKKKFFFFVDDLVN----------------ENNDTESSDVS-----NN GDISKIPLKRKMDIELNLAQILPKEKLPKNISPKWFIWSKDD------------------ ----------------IAYQRLVDRLKSQAYMFESENFFKKVQDFTCVSLQMSPYCDDDL IQRFCETITAINSPIKKITFGIDTCVHNELFDNKLRWTTI-PFDASKLLDQKENTNLIYS SITGNEFEMNFTQDSILNANI-IDDLPLYCQIPANIHILSLFEIIRELKLSECNAQST-- ---------MSEYLGKINKYAEIYNGV--AYREVLEDHCKFPLTFLLNMNSKSPKQGTII LLSNEE-----TDELYKDKNKTKFNI----CNNLTFIDISKE------------------ ------------------------------------------------------------ ---------------------------------------FKYCNQYKQIINAITEDYNVK KN---------------------------------------------EYDLIYIDSYCHL VPTFS-LGQFEVEESFNLVTDIMIALNLIKFGG---------NI---------------- -----I-ISLKTALTRFT----AGIIIVL-SSVFDKIALSK---PYSSSSPCYSNFYLIC SGFNDHS-NTLSRHFFQFLWDVFSNNIKENTS---------------------------- IVQCVPPTLF-------ASDNFLHWLKEFNNEVMLYDIEMLEAVIEQQESSDHLGLNISN CGKRQKNTDSNWEDFTNRVSIQREILRYILIGANSLSSDEAFLKLYGQTK---------- -----------------------ESCDTFKMEKMEENHKTLSEGDQNLI--DINILQNDG QYPN--------------------FLEQMNVH--RLEESQSNKNIDPFEDQVDLNKEIDV FCISPEIEYNDPFAQNN---------- >71027093|Thepar|Alveolata ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MSSQSGSNQ-TLHNN-- ------------------------------------------------------------ ------------------------------------------------------------ -------------KRFVFRSNLNRLF---------------------------------- --SDTKIFPP----------------SSNPCSKCILKKKPCICNIINSSVG--------- ----RTKRYEID--ELNETKCMLNDLRNVLNDVD-------------------------- ----LEKWSTHTKLLDNTSL-VIKHLADLKLNVNGRNESG---------VELVTNAWLKF YEILEVYKLVEYLKPNFKT------------EGGTLTSVHISECPGAFIASLNHNLKSKN ---------YNGELKWF-ATSLNPYYEGNNHNVVLAEDI--------------------- --------------------------------------LLKETYQNWLLG--------YD NSGNITKSCN-IEYIWDHISRPGRYNKSKQPL---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------LADLATADGSFNCQFD----------------PNNQELLTSPLKFADVV CALGLLRVGGCFIIKMF-NLFEEPSMSIIALLSLCFKRLEVYKPFLSREANSEVYVICLD FNGI-TSILLSSLCKFVDQYST-------------------------------------- -----------NQSNMS--IIPKEWIPSAFRAEFADCARMFAEIQFRSLRNALS---LYK T-VLNENPY-----------------------------------------------YKEK REFANSF--------IKHFNIVPISP------EFRLVKRAHFGEYLISGKDTCSLGHLE- -----------KNYFSKFEDRQEYY-NLYNSLQRKRVENKTAKDVYLNTND--------- -------------GDNVEEYVRS------------------------------------I KAVVDFVNKSKVKLLENRVDSGDRVELLFKLDEEVYES---------------------- ------------------------LLDDLKNQRYLKENWFGIGNMNCEDFKFSFFCNNDL LF-YLIYLKSCCCSNIPLTTLQECLEKSSSYGEALTDLNSFPNSCTVHLAFVFKN----- ----FLNINRYKYYLEITSNDFQQFPSVSLLKRYNVTGSVIYNQTTNIHDKVNSTSDS-- ---------PNSTNNMNNSVNGSNLFIFENIFELQTILNNFPGDGNIELCFEFNYYNLFN SNQSYKSL---------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------------IGEILESNL KR---------------------------------------------NCDFIFCDPYN-N VN-YRELLYKELNTKYILVAQLIQALNCLNDNG---------DL---------------- -----V-LRIFSLFTRFT----TGILCCL-STVFDEVILYR----PESVVNWSQEVFVIC KNYKDKD-NSICRHFFQCLWDALALHHKTHQT---------------------------- LLQIIKPFHF---------TTIAKKLYDFNNLLLNKELSELLN---KENVIKEHLNGSKE FLNKFKLLDILYPNKLPDQS-EVHLL---------------------------------- --------------------------------------KLQYKNETSCTVNNFKR----- -----------------------------------------KMTDSPQITESESESNSPI WSDDNLDDDFN---------------- >85000303|Theann|Alveolata ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MSSQSGLNQ-TLYNN-- ------------------------------------------------------------ ------------------------------------------------------------ -------------KRFVFRSNLNRLF---------------------------------- --SDTKKFPP----------------SSNPCSKCILKKKPCICHIINSSVGSYVTEGIDS QIWYRTKRYEID--ELNETKCMLNDLRNVLNDVD-------------------------- ----LEKWSTHTKLLDNTTL-VIKHLADVLFLHTLYILKLNVNGRNESGVELVTNAWLKF YEILEVYKLVEYLKPNFKT------------EGGTLTSFHISECPGAFIASLNHNLKSKN ---------YNGELKWY-ATSLNPYYEGNNHNVVLAEDI--------------------- --------------------------------------LLKETYQNWLLG--------YD NSGNITKSCN-IEYIWDHISRPGRYNKSKQPL---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------LADLATADGSFNCQFD----------------PNNQELLTSPLKFAEVV CALGLLRVGGCFIIKMF-NLFEEPSMSIIALLSLCFKRLEVYKPFLSREANSEVYVICLD FNGI-TSILLSSLCKFVDKYSN-------------------------------------- -----------NQNNVS--IIPKEWIPAGFRAEFVDCAKMFAEIQFRSLRNALS---LYK T-VLNENPY-----------------------------------------------YKEK REFANAF--------IKHFNIVPISP------ELRLVKRAQFGEYLISGKDTCSLGHLD- -----------KNYFSKFEERQGYH-NLYNSLQKKRLENKASKDIYLQISD--------- -------------GDNVEEYGRS------------------------------------I REVVDFVNKSKVKLLENKADSGDRVELLLKLDEEVFES---------------------- ------------------------LLDDLKNQRYLKENWFGIGNMNCEDFKFSFFCNNDL LF-YLIYLKSHCCSKIPLTTLQECLEKSSSYGEALTDLNSFPNSSTIHLAFIFKN----- ----FLNVNRYKYYLEITSNDFQQFPSISLLKCYNITGSILYNQMNHTSDG-NSNSHV-- ---------NSYPDNVNN-VNGSNLFIFENIFELQTILNNFPGDGNVELCFEFNYYNLFN SNQSYKSL---------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------------IGEILESNL KR---------------------------------------------NCDFIFCDLYN-N VN-YRELLYKELNTKYILVAQLIQALNCLNDNG---------DL---------------- -----V-LRIFSMFTRFT----VGILCCL-STVFDQVILYR----PESVVNWSQELFVIC KNYKDKD-NSICRHFFQCLWDALALHHKTQQT---------------------------- LLQIIKPFHF---------TTIAKKLYDFNNLLLNNELCELLN---KEAVIKEHLTGSKE FLNKFKLLDILYPNKLSDHS-DVQLL---------------------------------- --------------------------------------KLQYMNETSCTVNNFKR----- -----------------------------------------KMTHSPQVTESESESNSPI WSDDNLDDDFN---------------- >68074343|Plaber|Alveolata ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------MNHIFSFDNNLNNIF---------------------------------- --LGDYIEKS-----------------ESSCEYCTKRKRVCRCDTMKRELG--------- ----SERTKDID--EFLNLKKYYDEICEKI------------------------------ ----VDKYKDVVNRFEYDKD-IVIYIKKNKIN-----------------DEIECEDWLYF YELLKERKVLEKCIDLKQEKE-----------IISLNSFHLDEQAN-FISCLNYYIKVNK Y--------HNIHHNWM-GMSINPFNEYANNNYNPNVCTNIQTN-QFNNVNNINDKIFND DCNVYSIE-ESEKIHNIISPGDL-----KN-IHPLYYYSYIQDNEKWLSG--------IN NSGNILHLEN-IDYVWNKTVREDSNKIK-------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------LFHLITANCVKNNDMDYNKIKTKKEYNE--NDINVNIEIERVLCISQLV CALGMMNIGGYFIMKIK-LSFDNFLLSVFSILSICFKKLEVYRPSCCYLRNI-IFVIGVH FNGI-TSIFLSSLKNCVEESQKELINLVNSTRKEDHSKEKSDNTEMKNKKVKTTNNSVYS DISPITKSESSKFLNHS--LIPRKWIKSSFFQEYKNCINHFIDYLIYHLKKCIN---LSN INLIKKNI------------------------------------------------ENTK NTYISQF--------FEEHKIVDILK--KDKLVHKLLDHIYYEN-CLDEKNNRFNDFGEK -----------DDEIDFILPNNLL-ENSE-EIFFSN---------KFFSKIKNSILH--- -----------YQLDEKGIYFKN------------------------------------N YNINIYCNNNIENYRKNITSLLKKIKFKNVSN---------------------------- -----------------------------------INKATELFQLDQDILKKKVFLRDKG LF-SNHEMEFINLLKKQAYFTNKNWFKCYLQNDILNFKNPFYSSK-NLFKDLLKC----- ----RYYIYYKNCDIHINSFKQILKQYEPISTSYIH--YELYSSVIDCLFV--------- ----------------LKNCAGFDIFKDSSFIQNFLVIS--TENCIFNFFTKFQTGYYVA LESNDP------------------------------------------------------ ------------------------------------------------------------ ------------TSINSNYTNSGTESNTDDYVIHVNVGNMYEKRQSYKLFSELLIQKLKS KN---------------------------------------------VCSFIYIDLNT-I FPNYVHLVEKEIKVKNYFISSLIIAFNYLKKEG---------NM---------------- -----I-IRLSSVLTFFT----VGLVYIL-FCCFEKVSFFV----PPSCDDINLDFYIYC FNFNE---NYIYRHYIQYIWDAVICNQHINEK-FNSKEMGMNTITSKSLETG--SKKRKS DIYFSIPLYFV------MNKHFVLFIKKFNSFYIKNHINICLNFIKEPKYFNHHKSMIKS LLTNFFKAYIL---CDDSYEKIYKSITIHYN----------IFHKKEDIS---------- -----------------------DDEDEDEEDEKIDKHENFNNLEDESGNNNFKHLFDLR -----------------------------------DKKKNDIWEVNKYENSSGESDYSLI YEYKNVPSEVSISETAWDSP------- >124505747|Plafal|Alveolata ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------MNHLFSFQINLNDIF---------------------------------- --TGDNIKKS-----------------ENSCDYCIKRKRVCKCDTIKEELG--------- ----SEHIAILN--DLVDLKKYYDEVCEKI------------------------------ ----VDKYQDVVHRFEYDKD-IVKYIKKHNIN-----------------DEIECVDWLYF YELLKERKILENIINTKEDKD----------NVTSLNSFHINEEAN-FISCINYYLKINK Y--------NNVQHNWM-GMSLNPFNEYINNNYNFDIFNKNEN---IDDINKEKKNDFLN YHSLLKMKNEKEDIYNERKKDDILLYKDKKFYPLYYYSYILYENEKWISG--------IN NTGNILHLEN-IEYVWNKTVRE-GNKIK-------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------LFHLITCDCLKIKDIHNIYMNNKEISKDKIKIIEESIHIERILCISQLV CSLGMINIGGCFIMKIK-LSFDNFLLSIFSILSICFKKVDVYRPSCCYLQNV-IFLIGIH FNGI-TSIFLSCLNNWVQLAQKEIVPLLSCNDKYNVEDNIGNVKENEQKKIKLNDNILHD NRKEHTMWD---YINHS--IIPLKWIKSNYLKEYKNCINHFIEYIIYELKKCIN---VSN ISLIKKNI------------------------------------------------ENTK NTYISQF--------FEEHKIIDIKK--KDKLIYKLMDHIYEDVNLLNERYHEENKDKIN -----------DHKYNNIDNVSISSEDINNETFFNNNINNA--DNKNWLKINNSIL---- -----------YETEEKGIYFRN------------------------------------T YYKNNYCNENIKKYRKKITALLKKIKFKNISNNHDNNINLEDEDDINEN----------- -----------------------KKKTNNYHNNNNNNNKNELFQLDEYIIKKRKFSMDKN LI-LKHHLEFENLLKKQVYFTNKNWFKSYLHNNVDKYNNSFFLKKKNTFKDILKC----- ----RYYLYYNNYDIHINSFKQILKQYEPLNISYIN--YELHANVIDCLFT--------- ----------------LTNCANLNIFQNSLFLQQFIVIS--NEQNVYNFFSKFQSGHYVY FDAKIQ------------------------------------------------------ ------------------------------------------------------------ ------------SHILSEHGSKK--RGADHSETFLNLDDMYENTKSYKAISELLISYIKD KN---------------------------------------------SCSFIYIDMNS-I YPNFVDVVEKELKIKNYLVGSLIIAYNFLKKNG---------NM---------------- -----I-IRLSSVLTFFT----AGLIYIL-FCSFDKIEFFV----PPSCDDISLDIFLYC HNFNE---NYIYRHYIQFIWDALICNKHIDEK-LFNMDE------KKKLDKPI-NKKRKA DLYFSVPMYYL------MNKHFVMFLKKFNSFYFKHHINVCLNFMKEPKYFYHNKILIKS LLTHFFKAYVI---QGKTFENVYKSIGMSFD----------NFYEGREDS---------- -----------------------DDEDEEDDEDEENKKEQEQEEEEEQEEEKEKTHEAYD --------------------------EEKSFKAFLHLNRKESHAKNQFEFYSSDSNYSIM CEYKNVPSEISISESAWDSS------- >221052352|Plakno|Alveolata ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------MNHTFTFETNLNDIF---------------------------------- --AGDEIAKS-----------------DKSCDYCLKRKRVCRCDTIRRELG--------- ----SEDAAEIA--ELQERKRYYDEICEKI------------------------------ ----VDKYKDVVNRFEYDKD-IVSYIKKNKIN-----------------DEVECEDWIYF YELLKERKIVERCIDTKQSKE-----------PFILNSFHFDEQAN-FISCLNYYLKVHK L--------HHVIHNWM-GMSVNPFDEYAQGEERHAVIDDRRDGAGVTVHAGSTPQQEHA KRERQSEPTRTGQIDVEHTITPITQKKGKK-FHPLYYYLYMQENEKWISG--------LN NSGSIIHPEN-ISHVWNQTVRESNKKVK-------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------LFRLITANSINTDDVMEYCKKGKREQH----IMEENNHTARITSISQLV CALGMVDIGGCFIIKMK-LSFDNFLLSIFSILGICFKKLEVYRPSCCHLRNV-VFLVGIH FNGI-TSIFLSSLNNWVLGAQREIAPHLGEG------NQLSTLG------TKISEDSNGG VKKGGS------FRGRN--VIPRKWIKKTFFREYQNCIHHFVDYLIYYLKKCIN---VSN TNLMKKNI------------------------------------------------ENTK RMYLSQF--------FDEQRLVDIRK--KDKLLFRLMDDLYLDHGRIILAVHHTDQADEE ---------NRADELDHMDKTDAHWEGNRKGCSRNSPYTGAPFSKKELQKLRSTLNLPA- -----------HAGTERSIFFEGTGESNE-------------------------TNENIS NGVSANRGVNVRKYRKQITALLRRIDFKGNKAS--------------------------- -----------------------SRKKRGSKINGADGTTSGLFQLDENLIRKRVFSVDKT LL-EKHEAEFEGLLKKQVYFTNKNWFRCYLQKEPWHFQNPFYLDK-ELYRDILLF----- ----REHIYYNKCDMGMNSIKQVLKRCEPVCSSYLMDGHEFCCSVIDCLFV--------- ----------------LRNCAHVDLTEDSSCLRNFLVISGDTSASVSSFFSKFGSGCHIL LQGSDD------------------------------------------------------ ------------------------------------------------------------ ------------Q-----VGEPQ------DVTSPLNVQELYERKTPYKYFSEMLKEKLGD KS---------------------------------------------VCSLVFIDLNTQL FQNYVHVVEKEIRTKNYLVSSLIICFNYLQKGG---------SL---------------- -----I-LHLSSAMTFFT----AGLLYVL-VCAFERVDLFL----PPSCDDIDLGFYIYC NNFSG---NYVYRHYVQFLWEALICNQHLEDK-VPGSSTN---VSITEGEVS--TKRKKG EVYLSVPLFFL------MNKHFVHLLKRFNSFYFSHHINVCMHFLREPKYFYHNRTLMKC LVTHFLRAYILPEEVRRSFGRVFKSVSIHCDEDGSD-----VLDSGDDESNTFGSD---- -----------HLPMGDDIESDFSSVDVPNGGEEVDGGRNGLKRDAASLDRN-KKKQKVR TTISTSRSRSRS----------RSRSRSRSRSRSGSGDKRVVNEESEVDCSSSESNYSLA FEYKNVPSEISVSETAWGESS------ >156095075|Plaviv|Alveolata ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------MNHTFTFETNLNDIF---------------------------------- --AGDDVAKS-----------------EKSCDYCVKRKRVCRCETIRRELG--------- ----SEDAAEIA--ELQERRRYYDEICNKI------------------------------ ----VGKYKDVVNRFEYDKD-VVSFIKKNKIN-----------------DEVECEDWIYF YELLKERRIVERCIDTKGGRE-----------AVTLNSFHFDEEAN-FISCLNYYLKVHK L--------HHVVHSWM-GMSVNPFDEYSPGGARHAGVG---HSGGVSGYGGDSDHVSGY GRDSDR---------VSGYARDAAAPEGKR-FHPLYYYLYVQENERWISG--------LN NSGRIIHPEN-INHVWNQTVRESNNKVK-------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------LFQLITANSVSADDVTDYCKREKKNQQ----VEEQNSHVSKIGSISQLV CALGMVDVGGCFIMKMK-LSFDNFLLSIFSILAICFKNLEVYRPSCCHLRNV-VFLVGVH FNGI-TSIFLSCLNNWVQGAQREVVSLLGEQ------HTLGMLGAIDSPGVSVPGDPPGG VDPGRS------FKGRS--IIPRKWIKQSFFREYQKCIHHFVDYLIYYLKKCIN---VSN TNLMKKNI------------------------------------------------EDTK RMYLSQF--------FEEHRLVDLRK--RDKLLSRLLDDLYFDLWRIIPPGSGESAEGGE KGESGESGENRESRENGADKGDHLEEADGEDCRKHFPYEGAPFSKKELQKLRSSLQLPP- -----------QAATERGIFFETRGPT--------------------------------T NGECANRGGSLHKYRKQITALLRRIDFKGDRAP--------------------------- -----------------------SRKRRGSRSNRVADPPRGLFQLDEDLIRKRVFSFDKA LL-EKHEAEFEGLLKKQAYFTNKNWFRCYLQKEACHFVSPFYLGK-DLYRDIQLF----- ----RQHIYYNQCDASINSLKQVLKRYEPVCSSYVMDGSELCSSVIDCLFV--------- ----------------LKNCAHVDLTEGCPFLQNFLVISGDASAGVFSFFSKFGSGCHVL LQGGGS------------------------------------------------------ ------------------------------------------------------------ ------------SGVGGVSGEPP------EAAPPLNVQELFQRKTPYKHFSELLKDRLEG KS---------------------------------------------VCPFVLIDLNTHL FPSYVHVAEKEIKTKSYLVSSLIICFNYLKKGG---------NL---------------- -----L-LHLSSALTFFT----AGLLYVL-VCAFDRVEFFL----PPSCDGIDLGFYICC HNFGG---NYVYRHYVQFLWEALICNQHLEEK-VPGSATS---VATTPGEAN--AKRKKG ELYLSVPLFFL------MNKHFVSLLKRFNSFYFTHHLNVCRHFLREPKYFYPNRTLVKC LVTHFFRAYVLPEGAGRSFGRVFKSVSIHCEEDGSDEDGSDALGSDQLDSDVLGSDQLDS DRLDSDNDGRGHLPVGDATGSDFSSLDVPSRGEGVDGGRRAPRGGASPPERNNKKKQKIR ----------------------RNRSRSGSLSGSGSGGARVASEGSEADGSSSESNYSLA FEYKNVPSEISVSETAWGDSS------ >229892013|Afrswi|dsDNA|Viruses ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MSNYYYYYGGGRY---------------------------------- DWLKTVEPTN-----------------FLKIGLPYQAHPLHLQHQA-------------- ----TTPPSILE--KFKRADILLNEVKAEMDPLMLQPET--------------------- ----EKKLFQILSSIDMFKG-LRKKVEFTYN------------------AQIVTNAWLKM YELLNTMNF-----------------------NNTSQAFCNCELPGGFISAINHFNYTMM ---------HYPTFNWV-ASSLYPSSETDALE-----DHYG------------------- --------------------------------------LYQCNPDNWLMQSPLLKKNMDY NNGDVTIASN-VKNLALRATQRLT------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------PIHLYTADGGINVGHD----------------YNKQEELNLKLHFGQAL TGLLSLSKGGNMILKHY-TLNHAFTLSLICVFSHFFEELYITKPTSSRPTNSETYIVGKN RLRLFTPKEEQVLLKRLEFFND-------------------------------------- ---------------TP--LVDLSLYQNLLESVYFAVETIHLKQQIEFLNFGMKCYRH-- --------------------------------------------------------FYNK IKLLNDY-------------LAPKKK---------------------------------- ----------------IFQDRWRV------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------LNKLYVL------------------------------- ------------------------------------------------------------ --------------------EKKHKLKLCAASQGSVA----------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------- >55819381|Acapol|dsDNA|Viruses MFIDKVTNKVNKSVDKTVLKTISKAKEYLSKGGLSLALSANKYEKLVPYNLWYNHELYQI TNYTQNNQNMRIRFYNEIMLSPIVSYNEHDLSKIKTLVPNMSLYQPFYPETFYSVWEFLQ SEYINQNAMNFLFIGKENKLGSVESLMIYNELYKNNYLNNTYTVWISDNESHDIFSNSYL LKLPKHNYLKQAFKINFLTNTNQLNVYDTIIIDAISQFDDIFDWSKEETDLHANLFYLFT SLKHLKKNTGSILFKFSMMSSQSWFYLFDILFGCFKEYEFFRPKCINPFNSEIYLYLNKF TGNIPKNNILNSILTNLYRQNVTKLFHLNLHHIDINPIFQKYLISRNKWIDNIIDYIDES PQQNNVCYVTKWHNKNNLLQIKDTTNYLDQNNDKYKLSNNSHPKIKSISHNF-------- ----LLDNNHFK--NLLQKRASLNFYKRVMDTRPSRIFLDMSMVHDFS------------ -NEYYVTWDYITGTLDFYKN-IKNDLKKQYN------------------GEMITTAWIKL YEILNEFPDIIP-------------------KKESVKSFHLCEAPGAFVSATHHYMYS-- ---------LGCELDWY-AQTLNPMYENKAL-----DDHYG------------------- --------------------------------------LMSLYPDKWLFGSK------NN NTGDITSSEI-IKSYASNKQLS-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------NIDFMTGDAGIYCRPN---------------CLNEQETVMAKINMGQIV CILACLSKGRSAVFKTFLPLTEPLNISLLNLLSSIFEELIFYKPGASNGSNSEIYIVLKS YKGI-SSSELEMLYLMLDDPKI-------------------------------------- -------------TSTS---FITDVICKNFFRSYIKIVSNLIDKQINCLQRNFYYYYN-I GELYDLKK------------------------------------------------NNIY SEYYDEW--------FNKNKVVYLEN---------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------TLFS--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ 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