Small Molecules Targeting Hepatitis C Virus-Encoded NS5A Cause Subcellular Redistribution of Their Target: Insights into Compound Modes of Action
J. Virol. Targett-Adams et al. 85: 6353

Supplemental material

Files in this Data Supplement:

  • Supplemental file 1 - Fig. S1 (Structures of compounds used in the present study.)
    Fig. S2 (NS5A is not affinity-captured from Huh-7.5 cells expressing an NS3-5B polyprotein.)
    Fig. S3 (NS5A inhibitors do not affect the RNA-binding ability of NS5A.)
    Table S1 (Changes in the NS5A primary sequence in response to prolonged treatment with NS5A-targeting molecules.)
    Table S2 (The S2197P tissue culture-adaptive mutation in NS5A does not affect NS5A inhibitor efficacy.)
    PDF file, 124K.