The Interaction between Nesprins and Sun Proteins at the Nuclear Envelope Is Critical for Force Transmission between the Nucleus and Cytoskeleton

Supplemental Data

Files in this Data Supplement:

• Supplemental Data (.pdf, 348 KB) - Supplemental Experimental Procedures, 4 Figures, and 5 Movie Legends
• Supplemental Movie 1 (.mov, 170 KB) - Movie 1. Microneedle manipulation assay in a mouse embryonic fibroblast.
• Supplemental Movie 2 (.mov, 293 KB) - Movie 2. Induced nuclear and cytoskeletal deformation during microneedle manipulation in a mCherry expressing fibroblast.
• Supplemental Movie 3 (.mov, 365 KB) - Movie 3. Induced nuclear and cytoskeletal deformation during microneedle manipulation in a dominant negative KASH expressing fibroblast.
• Supplemental Movie 5 (.mov, 38 KB) - Movie 5. Nuclear deformation in response to substrate strain application.
• Supplemental Movie 4 (.mov, 112 KB) - Movie 4. Nuclear deformation in response to substrate strain application.