An active kinase domain is required for retention of PKCθ at the T cell immunological synapse

Supplemental Materials

This article contains the following supporting material:

• Supplemental Materials
• Movie01 - Movie S01. WT PKCq efficiently translocates to and remains stably enriched at the IS.
• Movie02 - Movie S02. PKCq-KRTE is weakly recruited to the IS. Enrichment quickly spreads around the entire plasma membrane, consistent with poor retention of KRTE at the IS.
• Movie03 - Movie S03. A second example of weak recruitment and poor retention of KRTE at the IS.