Structures of two molluscan hemocyanin genes: Significance for gene evolution -- Data Supplement - Supplemental DataSupplemental Data -- Proceedings of the National Academy of Sciences

Supplementary material for Lieb et al. (April 3, 2001) Proc. Natl. Acad. Sci. USA, 10.1073/pnas.071049998

Supplemental Figure 6 Fig. 6.
A schematic of the three-dimensional structure of functional unit OdH-g, showing the locations of all internal introns from both hemocyanins. Internal introns (designated by the respective exon pair) found in any OdH_G FUs are in blue, those in any HtH1 FUs are in red. Note that these are highly concentrated in the a-helical, copper-binding core domain (N-terminal part of the FU); only one intron lies in the b-sandwich domain (C-terminal part of the FU), and none are in the hinge region (a15-b1). Most, but not all, lie in interhelix loops. The two copper atoms are drawn as black spheres. The carbohydrate side chain is marked by a black arrow. Three-dimensional structure according to Cuff et al. [Cuff, M. E., Miller, K. I., van Holde, K. E. & Hendrickson, W. A. (1998) J. Mol. Biol. 278, 855–870].