Role of Net Charge on Catalytic Domain and Influence of Cell Wall Binding Domain on Bactericidal Activity, Specificity, and Host Range of Phage Lysins

Supplemental Data

Files in this Data Supplement:

• Supplemental Table 1 and Figs. 1-2 (.pdf, 1.2 MB) - Supplemental Table I. DNA oligonucleotide sequences used for cloning and mutagenesis in this study. Supplemental Fig. 1 Quality control of XlyACAT and its gain-of-function mutants. Supplemental Fig. 2 Melting profiles of PlyL provides no evidence for significant interaction between the catalytic domain and CBD.