Supplemental Data
Files in this Data Supplement:
- Supplemental Figures 1-5 (.pdf, 4.8 MB) - Supplemental figure 1. Knock down of syntaxin 6 in endothelial cells does not degrade α1β1, α2β1, αvβ3, αvβ5 and α4β1 integrins. Supplemental figure 2. Inhibition of syntaxin 6 does not affect endothelial cell spreading on collagen (type I), laminin-1 and, vitronectin. Supplemental figure 3. Lysosomal proteases inhibitor treatment does not rescue syntaxin 6-inhibition-induced reduction in FAK phosphorylation, Rac1 activation and, cell spreading on fibronectin. Supplemental figure 4. Syntaxin 6 knockdown blocks spreading of endothelial cells on fibronectin. Supplemental figure 5. Original linescans generated from images shown in figure 7B.