Gene number Fraction (t-score>0) P<0.001 "Fraction (t-score>0, P<0.001)" KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_CHONDROITIN_SULFATE 19 0.842105263 8 1 KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_KERATAN_SULFATE 15 0.733333333 1 1 KEGG_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI_ANCHOR_BIOSYNTHESIS 25 0.88 9 1 KEGG_LINOLEIC_ACID_METABOLISM 26 0.5 2 1 KEGG_ALPHA_LINOLENIC_ACID_METABOLISM 16 0.5625 1 1 KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_GLOBO_SERIES 14 0.857142857 4 1 KEGG_RIBOSOME 39 0.897435897 19 1 KEGG_BASAL_TRANSCRIPTION_FACTORS 32 0.75 14 1 KEGG_DNA_REPLICATION 35 1 22 1 KEGG_NUCLEOTIDE_EXCISION_REPAIR 41 0.853658537 23 1 KEGG_MISMATCH_REPAIR 21 0.952380952 13 1 KEGG_HOMOLOGOUS_RECOMBINATION 27 0.925925926 15 1 KEGG_NON_HOMOLOGOUS_END_JOINING 12 0.75 5 1 KEGG_SNARE_INTERACTIONS_IN_VESICULAR_TRANSPORT 36 0.916666667 19 1 KEGG_DORSO_VENTRAL_AXIS_FORMATION 22 0.863636364 10 1 KEGG_CIRCADIAN_RHYTHM_MAMMAL 13 0.769230769 3 1 KEGG_MATURITY_ONSET_DIABETES_OF_THE_YOUNG 23 0.608695652 2 1 KEGG_LEISHMANIA_INFECTION 61 0.885245902 31 1 KEGG_ALLOGRAFT_REJECTION 33 0.939393939 21 1 KEGG_GRAFT_VERSUS_HOST_DISEASE 34 0.911764706 20 1 KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY 93 0.838709677 38 0.973684211 KEGG_CHEMOKINE_SIGNALING_PATHWAY 173 0.722543353 68 0.970588235 KEGG_CHRONIC_MYELOID_LEUKEMIA 71 0.788732394 29 0.965517241 KEGG_ACUTE_MYELOID_LEUKEMIA 55 0.8 26 0.961538462 KEGG_CELL_CYCLE 116 0.827586207 47 0.957446809 KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY 47 0.893617021 23 0.956521739 KEGG_JAK_STAT_SIGNALING_PATHWAY 142 0.73943662 45 0.955555556 KEGG_PROTEASOME 40 0.9 22 0.954545455 KEGG_RIG_I_LIKE_RECEPTOR_SIGNALING_PATHWAY 63 0.80952381 22 0.954545455 KEGG_AUTOIMMUNE_THYROID_DISEASE 43 0.837209302 22 0.954545455 KEGG_AMINOACYL_TRNA_BIOSYNTHESIS 41 0.804878049 21 0.952380952 KEGG_TYPE_I_DIABETES_MELLITUS 38 0.815789474 21 0.952380952 KEGG_ANTIGEN_PROCESSING_AND_PRESENTATION 70 0.771428571 37 0.945945946 KEGG_MTOR_SIGNALING_PATHWAY 47 0.70212766 18 0.944444444 KEGG_PRIMARY_IMMUNODEFICIENCY 34 0.823529412 18 0.944444444 KEGG_SPLICEOSOME 119 0.789915966 51 0.941176471 KEGG_P53_SIGNALING_PATHWAY 65 0.830769231 34 0.941176471 KEGG_TGF_BETA_SIGNALING_PATHWAY 83 0.578313253 17 0.941176471 KEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY 121 0.79338843 63 0.936507937 KEGG_LONG_TERM_DEPRESSION 65 0.676923077 15 0.933333333 KEGG_RNA_DEGRADATION 54 0.87037037 29 0.931034483 KEGG_RNA_POLYMERASE 27 0.888888889 14 0.928571429 KEGG_BASE_EXCISION_REPAIR 31 0.870967742 14 0.928571429 KEGG_NOTCH_SIGNALING_PATHWAY 45 0.822222222 14 0.928571429 KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS 90 0.811111111 42 0.928571429 KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION 242 0.694214876 82 0.926829268 KEGG_ASTHMA 25 0.8 13 0.923076923 KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY 57 0.807017544 25 0.92 KEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM 27 0.777777778 12 0.916666667 KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS 124 0.806451613 48 0.916666667 KEGG_INTESTINAL_IMMUNE_NETWORK_FOR_IGA_PRODUCTION 43 0.813953488 24 0.916666667 KEGG_VASOPRESSIN_REGULATED_WATER_REABSORPTION 43 0.651162791 11 0.909090909 KEGG_THYROID_CANCER 29 0.655172414 11 0.909090909 KEGG_PYRIMIDINE_METABOLISM 92 0.858695652 50 0.9 KEGG_AMINO_SUGAR_AND_NUCLEOTIDE_SUGAR_METABOLISM 42 0.785714286 20 0.9 KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY 107 0.794392523 50 0.9 KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY 74 0.77027027 37 0.891891892 KEGG_NEUROTROPHIN_SIGNALING_PATHWAY 122 0.704918033 44 0.886363636 KEGG_VIRAL_MYOCARDITIS 66 0.787878788 35 0.885714286 KEGG_N_GLYCAN_BIOSYNTHESIS 42 0.785714286 16 0.875 KEGG_COLORECTAL_CANCER 62 0.677419355 24 0.875 KEGG_RENAL_CELL_CARCINOMA 67 0.776119403 32 0.875 KEGG_OOCYTE_MEIOSIS 103 0.699029126 30 0.866666667 KEGG_BLADDER_CANCER 42 0.738095238 22 0.863636364 KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION 108 0.657407407 29 0.862068966 KEGG_PANCREATIC_CANCER 69 0.724637681 29 0.862068966 KEGG_PROTEIN_EXPORT 22 0.772727273 7 0.857142857 KEGG_HEDGEHOG_SIGNALING_PATHWAY 54 0.518518519 7 0.857142857 KEGG_HEMATOPOIETIC_CELL_LINEAGE 78 0.679487179 28 0.857142857 KEGG_FC_EPSILON_RI_SIGNALING_PATHWAY 76 0.644736842 27 0.851851852 KEGG_GNRH_SIGNALING_PATHWAY 95 0.610526316 20 0.85 KEGG_ENDOMETRIAL_CANCER 52 0.711538462 20 0.85 KEGG_APOPTOSIS 84 0.75 39 0.846153846 KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION 78 0.717948718 26 0.846153846 KEGG_PURINE_METABOLISM 148 0.72972973 63 0.841269841 KEGG_OLFACTORY_TRANSDUCTION 106 0.41509434 6 0.833333333 KEGG_TYPE_II_DIABETES_MELLITUS 45 0.6 12 0.833333333 KEGG_PRION_DISEASES 33 0.636363636 12 0.833333333 KEGG_GLIOMA 64 0.71875 24 0.833333333 KEGG_BASAL_CELL_CARCINOMA 54 0.537037037 6 0.833333333 KEGG_MELANOMA 71 0.718309859 24 0.833333333 KEGG_PATHOGENIC_ESCHERICHIA_COLI_INFECTION 49 0.693877551 22 0.818181818 KEGG_PROSTATE_CANCER 86 0.720930233 33 0.818181818 KEGG_ABC_TRANSPORTERS 43 0.651162791 16 0.8125 KEGG_GAP_JUNCTION 84 0.69047619 31 0.806451613 KEGG_ERBB_SIGNALING_PATHWAY 83 0.698795181 41 0.804878049 KEGG_INSULIN_SIGNALING_PATHWAY 134 0.649253731 46 0.804347826 KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_HEPARAN_SULFATE 24 0.666666667 5 0.8 KEGG_ETHER_LIPID_METABOLISM 30 0.7 5 0.8 KEGG_DRUG_METABOLISM_OTHER_ENZYMES 36 0.611111111 10 0.8 KEGG_REGULATION_OF_AUTOPHAGY 28 0.607142857 5 0.8 KEGG_RENIN_ANGIOTENSIN_SYSTEM 17 0.411764706 5 0.8 KEGG_AMYOTROPHIC_LATERAL_SCLEROSIS_ALS 51 0.647058824 20 0.8 KEGG_CELL_ADHESION_MOLECULES_CAMS 124 0.669354839 59 0.796610169 KEGG_MELANOGENESIS 98 0.591836735 24 0.791666667 KEGG_SMALL_CELL_LUNG_CANCER 82 0.756097561 33 0.787878788 KEGG_PATHWAYS_IN_CANCER 317 0.659305994 113 0.787610619 KEGG_PENTOSE_PHOSPHATE_PATHWAY 26 0.730769231 14 0.785714286 KEGG_MAPK_SIGNALING_PATHWAY 255 0.62745098 73 0.780821918 KEGG_WNT_SIGNALING_PATHWAY 147 0.605442177 41 0.780487805 KEGG_FOCAL_ADHESION 196 0.693877551 68 0.779411765 KEGG_O_GLYCAN_BIOSYNTHESIS 29 0.75862069 9 0.777777778 KEGG_GLYCOSAMINOGLYCAN_DEGRADATION 21 0.619047619 9 0.777777778 KEGG_ONE_CARBON_POOL_BY_FOLATE 16 0.625 9 0.777777778 KEGG_VEGF_SIGNALING_PATHWAY 72 0.694444444 27 0.777777778 KEGG_LONG_TERM_POTENTIATION 67 0.641791045 22 0.772727273 KEGG_LYSOSOME 119 0.663865546 50 0.76 KEGG_NON_SMALL_CELL_LUNG_CANCER 54 0.703703704 25 0.76 KEGG_FRUCTOSE_AND_MANNOSE_METABOLISM 32 0.75 20 0.75 KEGG_OTHER_GLYCAN_DEGRADATION 15 0.666666667 4 0.75 KEGG_RIBOFLAVIN_METABOLISM 16 0.6875 8 0.75 KEGG_PANTOTHENATE_AND_COA_BIOSYNTHESIS 16 0.625 8 0.75 KEGG_SULFUR_METABOLISM 11 0.454545455 4 0.75 KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION 265 0.490566038 44 0.75 KEGG_ENDOCYTOSIS 174 0.66091954 72 0.75 KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION 111 0.648648649 47 0.744680851 KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS 86 0.686046512 39 0.743589744 KEGG_STARCH_AND_SUCROSE_METABOLISM 35 0.628571429 15 0.733333333 KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM 75 0.666666667 30 0.733333333 KEGG_ADHERENS_JUNCTION 72 0.583333333 15 0.733333333 KEGG_GALACTOSE_METABOLISM 26 0.576923077 11 0.727272727 KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 206 0.655339806 63 0.714285714 KEGG_AXON_GUIDANCE 128 0.640625 52 0.711538462 KEGG_GLYCEROPHOSPHOLIPID_METABOLISM 71 0.605633803 16 0.6875 KEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS 14 0.571428571 3 0.666666667 KEGG_STEROID_HORMONE_BIOSYNTHESIS 41 0.512195122 9 0.666666667 KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_GANGLIO_SERIES 15 0.6 6 0.666666667 KEGG_NICOTINATE_AND_NICOTINAMIDE_METABOLISM 22 0.636363636 9 0.666666667 KEGG_ECM_RECEPTOR_INTERACTION 80 0.7 23 0.652173913 KEGG_COMPLEMENT_AND_COAGULATION_CASCADES 66 0.621212121 33 0.636363636 KEGG_ARACHIDONIC_ACID_METABOLISM 49 0.510204082 16 0.625 KEGG_BIOSYNTHESIS_OF_UNSATURATED_FATTY_ACIDS 19 0.526315789 8 0.625 KEGG_INOSITOL_PHOSPHATE_METABOLISM 53 0.641509434 23 0.608695652 KEGG_CALCIUM_SIGNALING_PATHWAY 172 0.552325581 43 0.604651163 KEGG_GLUTATHIONE_METABOLISM 41 0.487804878 15 0.6 KEGG_TIGHT_JUNCTION 129 0.511627907 39 0.58974359 KEGG_ALANINE_ASPARTATE_AND_GLUTAMATE_METABOLISM 32 0.4375 12 0.583333333 KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY 64 0.578125 19 0.578947368 KEGG_EPITHELIAL_CELL_SIGNALING_IN_HELICOBACTER_PYLORI_INFECTION 65 0.523076923 28 0.571428571 KEGG_PEROXISOME 75 0.453333333 23 0.565217391 KEGG_LYSINE_DEGRADATION 43 0.511627907 18 0.555555556 KEGG_HUNTINGTONS_DISEASE 155 0.55483871 45 0.555555556 KEGG_PPAR_SIGNALING_PATHWAY 65 0.492307692 29 0.551724138 KEGG_GLYCOLYSIS_GLUCONEOGENESIS 59 0.423728814 26 0.538461538 KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC 73 0.520547945 13 0.538461538 KEGG_SPHINGOLIPID_METABOLISM 34 0.647058824 15 0.533333333 KEGG_DILATED_CARDIOMYOPATHY 88 0.511363636 17 0.529411765 KEGG_ALZHEIMERS_DISEASE 147 0.510204082 47 0.510638298 KEGG_CYSTEINE_AND_METHIONINE_METABOLISM 31 0.548387097 10 0.5 KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_BIOSYNTHESIS 11 0.545454545 4 0.5 KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_LACTO_AND_NEOLACTO_SERIES 26 0.538461538 4 0.5 KEGG_GLYOXYLATE_AND_DICARBOXYLATE_METABOLISM 14 0.428571429 6 0.5 KEGG_TERPENOID_BACKBONE_BIOSYNTHESIS 15 0.466666667 4 0.5 KEGG_LIMONENE_AND_PINENE_DEGRADATION 10 0.2 2 0.5 KEGG_NITROGEN_METABOLISM 23 0.260869565 6 0.5 KEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM 82 0.512195122 15 0.466666667 KEGG_GLYCEROLIPID_METABOLISM 46 0.413043478 13 0.461538462 KEGG_TRYPTOPHAN_METABOLISM 37 0.405405405 9 0.444444444 KEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450 51 0.470588235 9 0.444444444 KEGG_STEROID_BIOSYNTHESIS 16 0.25 7 0.428571429 KEGG_TASTE_TRANSDUCTION 43 0.465116279 7 0.428571429 KEGG_HISTIDINE_METABOLISM 28 0.5 5 0.4 KEGG_VIBRIO_CHOLERAE_INFECTION 54 0.407407407 20 0.4 KEGG_BETA_ALANINE_METABOLISM 21 0.19047619 8 0.375 KEGG_PARKINSONS_DISEASE 101 0.435643564 31 0.35483871 KEGG_ALDOSTERONE_REGULATED_SODIUM_REABSORPTION 42 0.452380952 20 0.35 KEGG_PHENYLALANINE_METABOLISM 18 0.444444444 6 0.333333333 KEGG_SELENOAMINO_ACID_METABOLISM 24 0.416666667 3 0.333333333 KEGG_PYRUVATE_METABOLISM 39 0.256410256 12 0.333333333 KEGG_FATTY_ACID_METABOLISM 40 0.35 16 0.3125 KEGG_TYROSINE_METABOLISM 41 0.463414634 10 0.3 KEGG_ARGININE_AND_PROLINE_METABOLISM 51 0.352941176 18 0.277777778 KEGG_GLYCINE_SERINE_AND_THREONINE_METABOLISM 31 0.225806452 11 0.272727273 KEGG_PRIMARY_BILE_ACID_BIOSYNTHESIS 16 0.375 4 0.25 KEGG_CARDIAC_MUSCLE_CONTRACTION 67 0.343283582 14 0.214285714 KEGG_RETINOL_METABOLISM 46 0.391304348 10 0.2 KEGG_DRUG_METABOLISM_CYTOCHROME_P450 53 0.471698113 10 0.2 KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_DEGRADATION 43 0.209302326 21 0.19047619 KEGG_BUTANOATE_METABOLISM 31 0.193548387 11 0.181818182 KEGG_OXIDATIVE_PHOSPHORYLATION 106 0.311320755 35 0.171428571 KEGG_PROPANOATE_METABOLISM 31 0.193548387 13 0.153846154 KEGG_CITRATE_CYCLE_TCA_CYCLE 28 0.071428571 11 0.090909091 KEGG_ASCORBATE_AND_ALDARATE_METABOLISM 12 0.416666667 1 0 KEGG_TAURINE_AND_HYPOTAURINE_METABOLISM 9 0.222222222 1 0 KEGG_FOLATE_BIOSYNTHESIS 10 0.3 1 0 KEGG_PROXIMAL_TUBULE_BICARBONATE_RECLAMATION 23 0.130434783 6 0