Menstrual Cycle–related Fluctuations in Breast Density Measured by Using Three-dimensional MR Imaging

© RSNA, 2011




 

Supplemental Figures

 

Fig E1

Figure E1: Representative MR images in 26-year-old premenopausal subject. The (left) original images and (right) the segmentation results on bias field corrected images are shown. Compared with the original images, the bias field corrected images have more uniform signal intensities between the medial and the lateral sides, and have stronger contrast between the fatty and the dense tissues. The measured FVs from week 1 to week 4 are 31.0, 32.9, 38.2, and 39.7 cm3, respectively. The corresponding PDs are 18.1%, 19.7%, 22.0%, and 24.2%, respectively. The CVs for the FV and the PD are 11.7% and 12.8%, respectively.

 

Fig E@

Figure E2: Representative MR images in 46-year-old premenopausal subject. The (left) original images and (right) the segmentation results on bias field corrected images are shown. Compared with the original images, the bias field corrected images have much improved uniform signal intensities between the anteromedial and the posterolateral sides and have stronger contrast between the fatty and the dense tissues. The measured FVs from week 1 to week 4 are 42.9, 43.9, 45.8, and 44.2 cm3, respectively. The corresponding PDs are 12.9%, 13.0%, 13.8%, and 13.1%, respectively. The CVs for the FV and the PD are 2.8% and 3.1%, respectively.

 

Fig E3

Figure E3: Representative MR images in 23-year-old premenopausal subject. The (left) original images and (right) the segmentation results on bias field corrected images are shown. The measured FVs from week 1, week 2, and week 3 to week 4 are 106, 109, 132, and 110 cm3, respectively. The corresponding PDs are 27.1%, 27.1%, 30.6%, and 28.7%, respectively. The CVs for the FV and the PD are 10.6% and 5.9%, respectively.

 

Fig E4

Figure E4: Representative MR images in 59-year-old postmenopausal subject. The (left) original images and (right) the segmentation results on bias field corrected images are shown. The measured FVs from week 1 to week 4 are 20.2, 20.8, 19.6, and 20.0 cm3, respectively. The corresponding PDs are 3.9%, 4.0%, 3.8%, and 4.2%, respectively. The CVs for the FV and the PD are 2.5% and 3.5%, respectively.