Files in this Data Supplement:
Supplementary Table S1 - Optimized ESI-MS parameters for detection of TCC and its metabolites in SRM mode.
Supplementary Table S2 - Activity of the microsomal preparations for the conjugation of 4-(trifluoromethyl) umbelliferone (TFMU) and trifluoperazine (TFP).
Figure S1 - Negative electrospray ionization product ion spectra of the TCC-glucuronide conjugates and Structures of the glucuronides
Figure S2 - LC-ESI-MS/MS chromatograms of microsomal incubations of TCC.
Figure S3 - Determination of KM and vmax values by fitting to the Michaelis-Menten function and utilization of various linearization methods.