Fraction of cells in each quadrant in 2D flow cytometry plots for TRAIL-treated HCT116 and SKW6.4 parental and derived cell lines stained with anti-cIC-S and anti-cEC-S antibodies,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Condition,count_cIC-Snegative_cEC-Snegative_well1,count_cIC-Spositive_cEC-Snegative_well1,count_cIC-Spositive_cEC-Spositive_well1,count_cIC-Snegative_cEC-Spositive_well1,percent_cIC-Snegative_cEC-Snegative_well1,percent_cIC-Spositive_cEC-Snegative_well1,percent_cIC-Spositive_cEC-Spositive_well1,percent_cIC-Snegative_cEC-Spositive_well1,count_cIC-Snegative_cEC-Snegative_well2,count_cIC-Spositive_cEC-Snegative_well2,count_cIC-Spositive_cEC-Spositive_well2,count_cIC-Snegative_cEC-Spositive_well2,percent_cIC-Snegative_cEC-Snegative_well2,percent_cIC-Spositive_cEC-Snegative_well2,percent_cIC-Spositive_cEC-Spositive_well2,percent_cIC-Snegative_cEC-Spositive_well2,count_cIC-Snegative_cEC-Snegative_well3,count_cIC-Spositive_cEC-Snegative_well3,count_cIC-Spositive_cEC-Spositive_well3,count_cIC-Snegative_cEC-Spositive_well3,percent_cIC-Snegative_cEC-Snegative_well3,percent_cIC-Spositive_cEC-Snegative_well3,percent_cIC-Spositive_cEC-Spositive_well3,percent_cIC-Snegative_cEC-Spositive_well3,average_percent_cIC-Snegative_cEC-Snegative,average_percent_cIC-Spositive_cEC-Snegative,average_percent_cIC-Spositive_cEC-Spositive,average_percent_cIC-Snegative_cEC-Spositive,standard_deviation_percent_cIC-Snegative_cEC-Snegative,standard_deviation_percent_cIC-Spositive_cEC-Snegative,standard_deviation_percent_cIC-Spositive_cEC-Spositive,standard_deviation_percent_cIC-Snegative_cEC-Spositive "Cell line, treatment, time point",cell count,cell count,cell count,cell count,percent of cells,percent of cells,percent of cells,percent of cells,cell count,cell count,cell count,cell count,percent of cells,percent of cells,percent of cells,percent of cells,cell count,cell count,cell count,cell count,percent of cells,percent of cells,percent of cells,percent of cells,average of percent of cells,average of percent of cells,average of percent of cells,average of percent of cells,standard deviation of percent of cells,standard deviation of percent of cells,standard deviation of percent of cells,standard deviation of percent of cells "HCT116, no treatment, 0 hr",10464,566,407,8,91.4%,4.9%,3.6%,0.1%,10117,385,264,5,93.9%,3.6%,2.5%,0.0%,11949,569,444,16,92.1%,4.4%,3.4%,0.1%,92.5%,4.3%,3.1%,0.1%,1.3%,0.7%,0.6%,0.0% "HCT116, 50 ng/ml TRAIL + 2.5 ug/ml CHX, 1 hr",5323,3882,2527,163,44.7%,32.6%,21.2%,1.4%,4210,3620,2178,64,41.8%,35.9%,21.6%,0.6%,5816,4961,2815,92,42.5%,36.3%,20.6%,0.7%,43.0%,34.9%,21.1%,0.9%,1.5%,2.0%,0.5%,0.4% "HCT116, 50 ng/ml TRAIL + 2.5 ug/ml CHX, 6 hr",106,1882,9484,109,0.9%,16.3%,81.9%,0.9%,67,1128,8227,59,0.7%,11.9%,86.8%,0.6%,423,2642,8813,585,3.4%,21.2%,70.7%,4.7%,1.7%,16.4%,79.8%,2.1%,1.5%,4.7%,8.2%,2.3% "OE-Bcl2 HCT116, no treatment, 0 hr",11788,689,156,4,93.3%,5.5%,1.2%,0.0%,11007,644,220,6,92.7%,5.4%,1.9%,0.1%,4259,608,100,2,85.7%,12.2%,2.0%,0.0%,90.6%,7.7%,1.7%,0.0%,4.2%,3.9%,0.4%,0.0% "OE-Bcl2 HCT116, 50 ng/ml TRAIL + 2.5 ug/ml CHX, 1 hr",2406,5703,233,6,28.8%,68.3%,2.8%,0.1%,4797,6667,366,8,40.5%,56.3%,3.1%,0.1%,2025,3730,193,1,34.0%,62.7%,3.2%,0.0%,34.5%,62.4%,3.0%,0.1%,5.9%,6.0%,0.2%,0.0% "OE-Bcl2 HCT116, 50 ng/ml TRAIL + 2.5 ug/ml CHX, 6 hr",219,7550,823,46,2.5%,87.4%,9.5%,0.5%,389,9949,1231,74,3.3%,85.5%,10.6%,0.6%,418,10816,1139,98,3.4%,86.7%,9.1%,0.8%,3.1%,86.5%,9.7%,0.7%,0.5%,1.0%,0.7%,0.1% "OE-Bcl2 HCT116, 50 ng/ml TRAIL + 2.5 ug/ml CHX, 24 hr",27,9898,453,2,0.3%,95.4%,4.4%,0.0%,133,9674,618,13,1.3%,92.7%,5.9%,0.1%,112,11787,548,10,0.9%,94.6%,4.4%,0.1%,0.8%,94.2%,4.9%,0.1%,0.5%,1.4%,0.9%,0.1% "deltaXIAP HCT116, no treatment, 0 hr",10705,556,392,31,91.6%,4.8%,3.4%,0.3%,3962,317,256,13,87.1%,7.0%,5.6%,0.3%,11168,509,399,35,92.2%,4.2%,3.3%,0.3%,90.3%,5.3%,4.1%,0.3%,2.8%,1.5%,1.3%,0.0% "deltaXIAP HCT116, 50 ng/ml TRAIL + 2.5 ug/ml CHX, 1 hr",4202,3513,4808,205,33.0%,27.6%,37.8%,1.6%,4950,3951,3942,124,38.2%,30.5%,30.4%,1.0%,4484,4349,3905,106,34.9%,33.9%,30.4%,0.8%,35.4%,30.6%,32.9%,1.1%,2.6%,3.1%,4.3%,0.4% "deltaXIAP HCT116, 50 ng/ml TRAIL + 2.5 ug/ml CHX, 6 hr",127,1555,10815,453,1.0%,12.0%,83.5%,3.5%,76,1374,10350,245,0.6%,11.4%,85.9%,2.0%,163,2120,10653,308,1.2%,16.0%,80.4%,2.3%,0.9%,13.1%,83.3%,2.6%,0.3%,2.5%,2.8%,0.8% "OE-Bcl2/deltaXIAP HCT116, no treatment, 0 hr",12952,413,180,12,95.5%,3.0%,1.3%,0.1%,12593,427,177,9,95.4%,3.2%,1.3%,0.1%,12009,329,222,6,95.6%,2.6%,1.8%,0.0%,95.5%,3.0%,1.5%,0.1%,0.1%,0.3%,0.2%,0.0% "OE-Bcl2/deltaXIAP HCT116, 50 ng/ml TRAIL + 2.5 ug/ml CHX, 1 hr",1699,3816,8666,117,11.9%,26.7%,60.6%,0.8%,1209,3327,8703,84,9.1%,25.0%,65.3%,0.6%,1965,3330,7500,393,14.9%,25.3%,56.9%,3.0%,12.0%,25.6%,60.9%,1.5%,2.9%,0.9%,4.2%,1.3% "OE-Bcl2/deltaXIAP HCT116, 50 ng/ml TRAIL + 2.5 ug/ml CHX, 6 hr",234,608,10403,322,2.0%,5.3%,89.9%,2.8%,209,502,11161,304,1.7%,4.1%,91.7%,2.5%,178,554,10718,247,1.5%,4.7%,91.6%,2.1%,1.8%,4.7%,91.1%,2.5%,0.3%,0.6%,1.0%,0.3% "SKW6.4, no treatment, 0 hr",8006,1892,1078,180,71.8%,17.0%,9.7%,1.6%,8401,2179,1236,163,70.1%,18.2%,10.3%,1.4%,7508,2174,1121,191,68.3%,19.8%,10.2%,1.7%,70.1%,18.3%,10.1%,1.6%,1.7%,1.4%,0.3%,0.2% "SKW6.4, 50 ng/ml TRAIL + 2.5 ug/ml CHX, 1 hr",8802,2011,1962,263,67.5%,15.4%,15.0%,2.0%,8962,2170,1901,243,67.5%,16.3%,14.3%,1.8%,6046,2036,1936,381,58.1%,19.6%,18.6%,3.7%,64.4%,17.1%,16.0%,2.5%,5.4%,2.2%,2.3%,1.0% "SKW6.4, 50 ng/ml TRAIL + 2.5 ug/ml CHX, 6 hr",2754,1450,7359,2825,19.1%,10.1%,51.1%,19.6%,2724,1391,6854,2977,19.5%,10.0%,49.1%,21.3%,2566,1531,7098,3081,18.0%,10.7%,49.7%,21.6%,18.9%,10.3%,50.0%,20.9%,0.8%,0.4%,1.0%,1.1% "OE-Bcl2 SKW6.4, no treatment, 0 hr",11710,267,1333,220,86.5%,2.0%,9.9%,1.6%,11181,257,1076,164,88.2%,2.0%,8.5%,1.3%,11735,290,1372,106,86.9%,2.1%,10.2%,0.8%,87.2%,2.0%,9.5%,1.2%,0.9%,0.1%,0.9%,0.4% "OE-Bcl2 SKW6.4, 50 ng/ml TRAIL + 2.5 ug/ml CHX, 1 hr",10509,286,2225,801,76.0%,2.1%,16.1%,5.8%,10094,277,2659,854,72.7%,2.0%,19.2%,6.2%,9042,173,2565,1697,67.1%,1.3%,19.0%,12.6%,71.9%,1.8%,18.1%,8.2%,4.5%,0.4%,1.7%,3.8% "OE-Bcl2 SKW6.4, 50 ng/ml TRAIL + 2.5 ug/ml CHX, 6 hr",229,90,9725,5139,1.5%,0.6%,64.1%,33.8%,266,94,9090,6294,1.7%,0.6%,57.7%,40.0%,108,45,10650,4167,0.7%,0.3%,71.1%,27.8%,1.3%,0.5%,64.3%,33.9%,0.5%,0.2%,6.7%,6.1%