Interactions between NKT cells and Tregs are required for tolerance to combined bone marrow and organ transplants

Supplemental materials for: Hongo et al

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• Figure S1. Transfer of CD4⁺CD25⁺ T cells, from wild type but not from CD1d^−∕− or IL-10^−∕− BALB/c mice restores peripheral blood chimerism in CD25 depleted heart transplant recipients conditioned with TLI and ATS (JPG, 126 KB) -
  (A) Two color analysis of sorted CD4⁺CD25⁺ T cells prior to adoptive transfer into Treg depleted and TLI/ATS conditioned wild-type hosts. (B) Mean percentages of donor type cells at day 100 after marrow transplantation in non-depleted wild-type BALB/c mice given heart and marrow transplants (Nondepl, N= 8 mice).