Identification of the Herboxidiene Biosynthetic Gene Cluster in Streptomyces chromofuscus ATCC 49982

Supplemental Material

Files in this Data Supplement:

  • Supplemental Figure 1 - Spectral data of herboxidiene and 18-deoxy-herboxidiene.
    MS Word document, 24K.
  • Supplemental Figure 2 - Bacterial strains and plasmids used in this study (Table S1).
    MS Word document, 33K.
  • Supplemental Figure 3 - Electrophoresis analysis of the PCR product amplified using primers A and B (lane 1) from the genomic DNA for the inactivation of AT4 in HerC (Fig. S1).
    MS Word document, 38K.
  • Supplemental Figure 4 - Disruption of herC by single-crossover homologous recombination and PCR analysis (Fig. S2).
    MS Word document, 161K.