Role of CYP2A5 in the Bioactivation of the Lung Carcinogen 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone in Mice

Data Supplement

Files in this Data Supplement:

• Supplemental Table and Figures -

  Supplemental Fig. 1: LC-MS detection of NNK metabolites formed by mouse liver and lung microsomes.

  Supplemental Fig. 2: MS/MS product-ion spectra of detected NNK metabolites.

  Supplemental Table 1: Kinetic parameters for the formation of NNK metabolites by WT A/J and B6 mouse lung and liver microsomes.