Expression, Immunogenicity, Histopathology, and Potency of a Mosquito-Based Malaria Transmission-Blocking Recombinant Vaccine

Supplemental material

Files in this Data Supplement:

• Supplemental file 1 - Fig. S1. SDS-PAGE, immunoblot, and RP-UPLC analyses of purified recombinant AnAPN1 produced in E. coli.
  PDF file, 188K.
• Supplemental file 2 - Fig. S2. Illustration of the relationship of the reliable detection limit when used as reactivity threshold to the standard calibration curve by 4-parameter logistic-log modeling.
  PDF file, 1.5 MB.
• Supplemental file 3 - Fig. S3. Pairwise sequence alignment of full-length Anopheles gambiae APN1 (AGAP004809) and human alanyl (membrane) amino peptidase (NP_001141.2).
  PDF file, 968K.