The Histone Deacetylase Inhibitor Valproic Acid Lessens NK Cell Action against Oncolytic Virus-Infected Glioblastoma Cells by Inhibition of STAT5/T-BET Signaling and Generation of Gamma Interferon

Supplemental material

Files in this Data Supplement:

• Supplemental file 1 - Supplemental figure legends
  PDF file, 50K.
• Supplemental file 2 - Fig. S1 (VPA administration in vehicle-treated mice does not alter immune cell infiltration.)
  Fig. S2 (Comparison of IFN-γ production by NK cells upon stimulation with cytokines or Toll-like receptor stimuli.)
  Fig. S3 (VPA does not alter the rate of encephalitis onset in mice treated with wild-type HSV.) PDF file, 154K.
• Supplemental file 3 - Table S1 (VPA coadministration with oHSV reduces the activation phenotype of recruited NK cells and macrophages.)
  Table S2 (Inflammatory cytokines in tumor tissue after either oHSV treatment or VPA treatment followed by oHSV administration.)
  PDF file, 160K.