Stretch-induced actin remodeling requires targeting of zyxin to stress fibers and recruitment of actin regulators

Supplemental Materials

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• Video 01 - Supplemental Video 1. Disruption of GFP-zyxin-containing stress fibers by Jasplakinolide (video1.avi). Zyxin-null fibroblasts expressing GFP-zyxin were treated for 2h with the actin stabilizer Jasplakinolide (200 nM) and images collected at 3 min intervals. Arrow indicates site of actin rupture corresponding to Figure 7J.