DNA Polymerase ζ Is a Major Determinant of Resistance to Platinum-Based Chemotherapeutic Agents

Supplemental Data

Files in this Data Supplement:

• Supplemental Data -

  Figure S1 - Time-dependent and dose-dependent induction of gamma-H2AX in REV3-deficient HeLa cells treated with platinating agents

  Figure S2 - Cisplatin-induced hyper-phosphorylation of Chk1 and RPA32 in REV3-deficient cells is dependent upon the ATR kinase

  Figure S3, S4, S5, and S6 - Time-dependent and dose-dependent induction and resolution of DSBs in REV3-deficient cells treated with cisplatin, oxaliplatin, picoplatin, and satraplatin