A Stretch of Polybasic Residues Mediates Cdc42 GTPase-activating Protein (CdGAP) Binding to Phosphatidylinositol 3,4,5-Trisphosphate and Regulates Its GAP Activity

Supplemental Data

Files in this Data Supplement:

  • Supplementary movie 1 (.wmv, 4.9 MB) - Movie 1. Fluorescent time-lapse movie of COS-7 cells expressing GFP-CdGAP(R56AN169V) treated with 10ng/ml PDGF. Images were captured every 20 seconds. The display is 3 frames per second. One second is equivalent to one minute real-time.
  • Supplementary movie 2 (.wmv, 3.7 MB) - Movie 2. Fluorescent time-lapse movie of COS-7 cells expressing GFP-CdGAP(17-1425) treated with 10ng/ml PDGF. Images were captured every 20 seconds for 10 minutes. The display is 3 frames per second. One second is equivalent to one minute real-time.