Figure 7. Densities of mature and immature spines.

Densities of NR1-only, GluR2-only, and NR1+GluR2 immunoreactive spines per 20μm dendrite segments from DIV10-26 neurons. Triple-colocalization of drebrin, NR1 and GluR2 was used to measure the density of NR1+GluR2 immunoreactive spines. The density of NR1-only (or GluR2-only) spines was obtained by subtracting NR1+GluR2 spine density from the total spine-localized NR1 (or GluR2) density. Data are presented as ± 95% confidence interval; p<0.05: * for NR1, # for GluR2, & for NR1+GluR2, n.s, no significance.