Characterization of the Viral O-Glycopeptidome: a Novel Tool of Relevance for Vaccine Design and Serodiagnosis

Supplemental material

Files in this Data Supplement:

• Supplemental file 1 - Table S1 (Overview of the synthetic strategies adopted in the present study to explore the viral O-glycopeptidome.)
  Table S2 (Peptides and O-glycopeptides prepared with Fmoc-SPPS used to produce microarray data.)
  Table S3 (MS data of the relevant bead hits from the OBOC library.)
  Fig. S1 (Principles of target (glyco)peptide enrichment on-chip.)
  Fig. S2 (Microarray data of Ala scan focused in the region 501-508 of gG-2 from full serum set.)
  Fig. S3 (Microarray data of Ala scan focused in the region 501-508 of gG-2 across the entire serum collection.)
  Fig. S4 (Microarray data for serum #4 from single- and multisite glycosylated analogues of gG-2 segment 491-510.)
  Fig. S5 (Inhibition assay with ⁵⁰¹PPA(GaINAc-a)TAPG⁵⁰⁷ on sera #60 and #14.)
  Supplemental methods
  PDF file, 2.0MB.
• Supplemental file 2 - Data: Collection of microarray serology data 1 Collection of microarray serology data 1
  MS Excel file, 2.6MB.
• Supplemental file 3 - Collection of microarray serology data 2 Collection of microarray serology data 2
  MS Excel file, 719K.