Analysis of Cryptococcus neoformans Sexual Development Reveals Rewiring of the Pheromone-Response Network by a Change in Transcription Factor Identity

Supporting Information for Kruzel, Giles, and Hull, 2012

Supporting Information

• Supporting Information - Figures S1-S5 and Tables S1-S4 (PDF, 3.6 MB)
• Figure S1 - The C. neoformans PRE shows variation in sequence among the instances identified (PDF, 70 KB)
• Figure S2 - PRE locations in promoters relative to the ATG (PDF, 60 KB)
• Figure S3 - The PRE identified in this study for C. neoformans var. neoformans shows similarity to an enriched sequence upstream of orthologous mating genes from C. neoformans var. grubii (PDF, 62 KB)
• Figure S4 - gpa3Δmat2Δ strains are sterile (PDF, 3.5 MB)
• Figure S5 - The deletion of MAT2 has no detectable effect the expression levels of numerous genes that lack PREs in their upstream regions (PDF, 68 KB)
• Table S1 - Strains, plasmids and oligos used in this study (PDF, 52 KB)
• Table S2 - Sexual development microarray dataset (PDF, 462 KB)
• Table S3 - Significantly enriched GO terms among Clusters 1-8 (PDF, 47 KB)
• Table S4 - Likely PRE targets among Cluster 1 (PDF, 40 KB)