Published July 23, 2012 // JCB vol. 198 no. 2 219-233
The Rockefeller University Press, doi: 10.1083/jcb.201202061

Atg9 vesicles are an important membrane source during early steps of autophagosome formation

Video 3.
Accumulation of Atg9 at the Golgi apparatus in cells depleted of Sec7. Video associated with Fig. S2 A. ATG9-2×GFP DRS2-TagRFPT cells and ATG9-2×GFP DRS2-TagRFPT SEC7-AID cells were treated with rapamycin for 30 min and then with 500 µg/ml IAA for 1 h. Images were analyzed by time-lapse microscopy at 32 ms/frame using an inverted microscope (IX71). In ATG9-2×GFP DRS2-TagRFPT SEC7-AID cells treated with IAA, Atg9-2×GFP formed immobile structures. WT, wild type.