Supporting Figure 7

Fig. 7.

Reduced survival of PtenloxP/loxP; MMTV-cre mice. Survival was markedly decreased in PtenloxP/loxP; MMTV-cre animals (triangles, n = 67) compared with control Ptenwt/loxP; MMTV-cre mice (squares, n = 35). All Pten mutant mice die by 14 wk, whereas the majority of control mice remain healthy.