Identification of Genes That Contribute to the Pathogenesis of Invasive Pneumococcal Disease by In Vivo Transcriptomic Analysis

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  Table S1. Real-time RT-PCR primers. Table S2. Primers for constructing in-frame Streptococcus pneumoniae WCH43 (serotype 4) mutants. Table S3. Differential gene expression profiles of S. pneumoniae WCH16 and WCH43 between nasopharynx and lungs and between lungs and blood by microarray analysis. Fig. S1. Heat map showing kinetics of regulated gene expression between the nasopharynx and lungs of mice infected i.n. with WCH16 and WCH43. Fig. S2. Heat map showing kinetics of regulated gene expression between the lungs and blood of mice infected i.n. with WCH16 and WCH43.

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