Fig 4.

Drop plate assays with DFD-VI-15. Both C. albicans CAF2 (upper panel) and S. cerevisiae BY4743 (lower panel) were inhibited by the compound at 2× the MIC₅₀. The concentrations of DFD-VI-15 used were 12 and 24 μg/ml for BY4743 and CAF2, respectively. Both strains showed hypersensitivity with the compound on yeast extract-peptone-glucose (YPD) or yeast extract-peptone-glycerol (YPG) medium (aerobic respiration). The antifungal activity of the compound was much less apparent when the strains were grown anaerobically (An).