Published September 3, 2012 // JCB vol. 198 no. 5 773-783
The Rockefeller University Press, doi: 10.1083/jcb.201203170

Neutrophil extracellular traps: Is immunity the second function of chromatin?

Video 2.
Time-lapse recording of neutrophils undergoing NETosis. Neutrophils were stimulated with PMA, and a z stack was generated for 2 h and 25 min on a confocal microscope. Directly labeled antibody fragments against NE (green) and chromatin (red) in the supernatant depict formation of NETs in the final phase.