In Silico and Intuitive Predictions of CYP46A1 Inhibition by Marketed Drugs with Subsequent Enzyme Crystallization in Complex with Fluvoxamine

Supplemental Data

Files in this Data Supplement:

• Supplemental Data - Supplemental Figure 1 - Unbiased sigmaA weighted 2|Fo|-|Fc| electron density...

  Supplemental Figure 2 - Photoisomerization of FLV in solution upon irradiation with UV light

  Supplemental Table 1 - Crystallographic statistics for the FLV-CYP46A1 complex

  Supplemental Table 2 - A summary of computational and intuitive predictions