The Adjuvant LT-K63 Can Restore Delayed Maturation of Follicular Dendritic Cells and Poor Persistence of Both Protein- and Polysaccharide-Specific Antibody-Secreting Cells in Neonatal Mice

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  Supplemental Figure 1. LT-K63 overcomes limited germinal center (GCs) induction in early life by accelerating the maturation...
  Supplemental Figure 2. CR1⁺, CXCL13⁺ FDC network and MOMA-2⁺ macrophages were detected in mice immunized with Pnc1-TT as neonates.
  Supplemental Figure 3. A weak TNF-α staining was detected in follicles 16 days after mice were immunized with Pnc1-TT+CpG1826 as neonates.
  Supplemental Figure 4. LT-K63 and CpG1826 enhanced vaccine specific IgG⁺ AbSCs in spleen and Abs in serum when co-administered with Pnc1-TT in neonatal mice.