Crucial Role of Gamma Interferon-Producing CD4⁺ Th1 Cells but Dispensable Function of CD8⁺ T Cell, B Cell, Th2, and Th17 Responses in the Control of Brucella melitensis Infection in Mice

Supplemental material

Files in this Data Supplement:

• Supplemental file 1 -

  Table S1. Oligonucleotide sequences used for RT-PCR.

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• Supplemental file 2 -

  Fig. S1 to S3 legends.

  PDF, 23K

• Supplemental file 3 -

  Fig. S1. Flow cytometry analysis of IFN-γ-producing cells in wild-type versus RAG^-/- and RAGγc^-/- C57BL/6 mice infected by B. melitensis.

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• Supplemental file 4 -

  Fig. S2. Flow cytometry characterization of splenic T cell populations from RAG^-/-, MHCII^-/-, and TAP-1^-/- mice.

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• Supplemental file 5 -

  Fig. S3. CD28 and CD40 costimulatory molecules appear weakly implicated in the control of B. melitensis infection.

  PDF, 189K