Files in this Data Supplement:
Supplemental Figure S1 - shows a steric clash between GlyH-101 in the predicted binding pose and an acetamide moiety covalently attached to a cysteine at position 338
Supplemental Figure S2 - illustrates the locations of charged residues in the extracellular vestibule of CFTR
Supplemental Figure S3 - illustrates reaction of S341C CFTR expressed in oocytes with NEM
Supplemental Figure S4 - shows the response of wt CFTR current to voltage jumps in the absence and presence of GlyH-101