The Rockefeller University Press, doi: 10.1083/jcb.201209044
Nonmedially assembled F-actin cables incorporate into the actomyosin ring in fission yeast
Podcast
biosights: November 26, 2012
Global sourcing for cytokinetic ring assembly
The Rockefeller University Press
biosights{at}rockefeller.edu
Fission yeast are thought to assemble their cytokinetic actomyosin rings from actin filaments nucleated at myosin-containing nodes around the cell equator. Using an improved actin-binding probe, Huang et al. find that actin cables are nucleated all over the cortex of mitotic fission yeast and are transported to the division site for incorporation into the contractile ring. This biosights episode presents the paper by Huang et al. from the November 26, 2012, issue of The Journal of Cell Biology and includes an interview with senior author Mohan Balasubramanian (Temasek Life Sciences Laboratory, Singapore). Produced by Caitlin Sedwick and Ben Short. See the associated paper in JCB for details on the funding provided to support this original research.
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