The Effect of Genomic Inversions on Estimation of Population Genetic Parameters from SNP Data

Files in this data supplement:

  • Supporting Information: Figures S1-S5, Files S1-S3, and Table S1 (PDF, 4.9 MB)
  • Figure S1: Distribution of inversion lengths of known human inversions (PDF, 92 KB)
  • Figure S2: LDhat recombination rate estimates at inversion breakpoints (PDF, 2.1 MB)
  • Figure S3: Distribution of standardised iHS statistic at different inversion frequencies compared to the null distribution (PDF, 237 KB)
  • Figure S4: The presence of inversions can be captured in the leading principal components (PCs) in an unstructured population (PDF, 121 KB)
  • Figure S5: The presence of inversions can be captured in the leading principal components (PCs) in a structured population (PDF, 1.9 MB)
  • File S1: Description of LDhat (PDF, 51 KB)
  • File S2: Description of iHS (PDF, 50 KB)
  • File S3: Description of SelSim (PDF, 55 KB)
  • Table S1: Median reduction in LDhat recombination rate estimates relative to the simulated rates (PDF, 59 KB)