New Insights into Structural Determinants for Prostanoid Thromboxane A2 Receptor- and Prostacyclin Receptor-G Protein Coupling

Supplemental material

Files in this Data Supplement:

• Supplemental file 1 -

  Tables S1 (Transmembrane regions of human TP and IP receptors) and S2 (Potential intermolecular interactions in TP-Gα peptide interface) and Fig. S1 (Saturation binding assays of wild-type TP and chimeric receptors), S2 (WT-TP and chimeric receptors in HEK293T cells), S3 (IP3 accumulation by WT-TP, WT-IP, and chimeric receptors), S4 (Gαq-mediated calcium signaling), S5 (Basal and agonist-independent calcium signaling), S6 (Amino acid sequence alignment of TP and IP), and S7 (Molecular model of Gαq bound to TP)

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