Supplemental File 1. Read alignments for the all snoRNA-derived miRNAs and 2 tRNA-derived miRNAs in human (hg19 build). 

>U60
CAGTCTGTGATGAATTGCTTTGACTTCTGACACCTCGTATGAAAACTGCACGTGCAGTCTGATTATTTAGCAAGACTGAGG
((((((.((.(((((......(((...((.(((...(((.......)))..)))))))).....))))).))))))))... (-17.50)
CAGTCTGTGATGAATTGCTTT............................................................       79    21      1
CAGTCTGTGATGAATTGCTTTGA..........................................................   479752    23      1
.AGTCTGTGATGAATTGCTTT............................................................     6610    20      1
.AGTCTGTGATGAATTGCTTTGA.......................................................... 23742894    22      1
..GTCTGTGATGAATTGCTTTG...........................................................     1532    20      1
..GTCTGTGATGAATTGCTTTGA.......................................................... 21953126    21      1
.........................................................TCTGATTATTTAGCAAGACTGAGG     4838    24      1
..........................................................CTGATTATTTAGCAAGACTGAGG     1408    23      1
...........................................................TGATTATTTAGCAAGACTGAGG     477     22      1
negative
>ACA25
AGTTCTCTATAGGAAGCCATAGCACTCCTAATGTTTGGTGCTATGTTTTCCTGAGGAGATATAAA
...(((((.(((((((.(((((((((..........))))))))).))))))).)))))...... (-26.70)
AGTTCTCTATAGGAAGCCATAG...........................................     6    22    1
AGTTCTCTATAGGAAGCCATAGC..........................................   753    23    1
.GTTCTCTATAGGAAGCCATAG...........................................    51    21    1
.GTTCTCTATAGGAAGCCATAGC..........................................  1233    22    1
..TTCTCTATAGGAAGCCATAGC..........................................     6    21    1
..TTCTCTATAGGAAGCCATAGCA.........................................    16    22    1
.........................................TATGTTTTCCTGAGGAGATAT...    13    21    2
.........................................TATGTTTTCCTGAGGAGATATA..    26    22    2
..........................................ATGTTTTCCTGAGGAGATATAAA    12    23    1
...........................................TGTTTTCCTGAGGAGATATAAA     1    22    1
negative
>ACA44
CCTGGAAAGACTTTGACAGCGCAGGTCAGTACAATACCTGCAAGCTGCCACTCAGCTTTCCTATA
...((((((.((.((.((((((((((.........))))))..)))).))...)))))))).... (-21.60)
CCTGGAAAGACTTTGACAGCG............................................	54	21	1
CCTGGAAAGACTTTGACAGCGC...........................................	201	22	1
.CTGGAAAGACTTTGACAGCGC...........................................	99	21	1
.CTGGAAAGACTTTGACAGCGCA..........................................	25	22	1
..TGGAAAGACTTTGACAGCGC...........................................	99	20	1
..TGGAAAGACTTTGACAGCGCA..........................................	41	21	1
..TGGAAAGACTTTGACAGCGCAG.........................................	39	22	1
........................................CAAGCTGCCACTCAGCTTTCCT...	1	22	1
.........................................AAGCTGCCACTCAGCTTTCCTATA	1	24	1
negative

>ACA36B chr1_220373880_220373961_-
GAACATTGAAACTGGCTAGGGAAAATGATTGGATAGAAACTATTATTCTATTCATTTATCCCCAGCCTACAAAATGAAAAAA
...((((......((((.((((...(((.(((((((((.......))))))))).))))))).)))).....))))...... (-24.40)
..........ACTGGCTAGGGAAAATGATTGG..................................................	4894	22	1
..........ACTGGCTAGGGAAAATGATTGGA.................................................	2347	23	1
...........CTGGCTAGGGAAAATGATTGG..................................................	937	21	1
...........CTGGCTAGGGAAAATGATTGGA.................................................	2545	22	1
............TGGCTAGGGAAAATGATTGG..................................................	96	20	1
............TGGCTAGGGAAAATGATTGGA.................................................	370	21	1
................................................TATTCATTTATCCCCAGCCTAC............	7863	22	1
................................................TATTCATTTATCCCCAGCCTACA...........	7584	23	1
.................................................ATTCATTTATCCCCAGCCTAC............	161	21	1
.................................................ATTCATTTATCCCCAGCCTACA...........	447	22	1
..................................................TTCATTTATCCCCAGCCTACA...........	110	21	1
..................................................TTCATTTATCCCCAGCCTACAA..........	23	22	1
negative
>ACA45 chr15_81221812-81221878_+
GAAAAGGTAGATAGAACAGGTCTTGTTTGCAAAATAAATTCAAGACCTACTTATCTACCAACAGCAA
.....(((((((((...((((((((..(.........)..))))))))..)))))))))........ (-22.60)
..AAAGGTAGATAGAACAGGTCTTG..........................................     638     23   1
..AAAGGTAGATAGAACAGGTCTTGT.........................................     232     24   1
...AAGGTAGATAGAACAGGTCTTG..........................................     60082   22   1
...AAGGTAGATAGAACAGGTCTTGT.........................................     26613   23   1
....AGGTAGATAGAACAGGTCTTG..........................................     31723   21   1
....AGGTAGATAGAACAGGTCTTGT.........................................     10994   22   1
........................................CAAGACCTACTTATCTACCAA......     20      21   1
........................................CAAGACCTACTTATCTACCAAC.....     52      22   1
.........................................AAGACCTACTTATCTACCAAC.....     23      21   1
.........................................AAGACCTACTTATCTACCAACA....     41      22   1
..........................................AGACCTACTTATCTACCAACA....     1795    21   1
..........................................AGACCTACTTATCTACCAACAG...     2381    22   1

>ACA47 chr17_75085389_75085575_+
TTTTGAATTTGCAGTAACAGGTGTGAGCATTCTAGCAGCAGTTTGATGATCATGTATGATACTGCAAACAGGACCTAC
(((((..(((((((((.((.(..(((.((((..(((....))).)))).)))..).)).))))))))))))))..... (-21.70)
......ATTTGCAGTAACAGGTGTGAG...................................................	11	21	1
......ATTTGCAGTAACAGGTGTGAGC..................................................	38	22	1
.......TTTGCAGTAACAGGTGTGAGC..................................................	81	21	1
.......TTTGCAGTAACAGGTGTGAGCA.................................................	42	22	1
................................................ATCATGTATGATACTGCAAACA........	22	22	1
................................................ATCATGTATGATACTGCAAACAG.......	121	23	1
.................................................TCATGTATGATACTGCAAACAG.......	34	22	1
.................................................TCATGTATGATACTGCAAACAGG......	20	23	1
..................................................CATGTATGATACTGCAAACAGG......	24	22	1
..................................................CATGTATGATACTGCAAACAGGA.....	902	23	1
...................................................ATGTATGATACTGCAAACAGG......	13	21	1
...................................................ATGTATGATACTGCAAACAGGA.....	372	22	1
....................................................TGTATGATACTGCAAACAGGA.....	326	21	1
negative
>U92 chr9_19063654_19063784_-
TAGAATAAACTGCCTTTTGATGACCGGGACGAATTGAGTGAAATCGTAACGGACAGATACGGGGCAGACAGATTTTAG
((((((...((((((..((.((.(((..((((.((.....)).))))..))).))..))..))))))....)))))). (-23.20)
......AAACTGCCTTTTGATGACCGG...................................................	1	21	1
......AAACTGCCTTTTGATGACCGGG..................................................	1	22	1
.......AACTGCCTTTTGATGACCGGG..................................................	1	21	1
.......AACTGCCTTTTGATGACCGGGA.................................................	1	22	1
........ACTGCCTTTTGATGACCGGGAC................................................	5	22	1
........ACTGCCTTTTGATGACCGGGACG...............................................	62	23	1
..............................................TAACGGACAGATACGGGGCAGA..........	336	22	1
..............................................TAACGGACAGATACGGGGCAGAC.........	111	23	1
...............................................AACGGACAGATACGGGGCAGAC.........	10	22	1
...............................................AACGGACAGATACGGGGCAGACA........	20	23	1
................................................ACGGACAGATACGGGGCAGACAGA......	31	24	1
.................................................CGGACAGATACGGGGCAGACAGAT.....	205	24	1
negative
>HBI-100 chr1_175937533_175937676_-
CCTACATAAATATATGGAGGTCTCTGTCTGGCTTAGGACAGCTGGCTAAGTCTGATCGTTCCCCTCCGTACAGCCTTTAA
............((((((((...(.(((.(((((((..(....).))))))).))).)....)))))))).......... (-21.60)
..........TATATGGAGGTCTCTGTCTGGC................................................	300	22	1
..........TATATGGAGGTCTCTGTCTGGCT...............................................	78	23	1
...........ATATGGAGGTCTCTGTCTGGC................................................	1019	21	1
...........ATATGGAGGTCTCTGTCTGGCT...............................................	926	22	1
............TATGGAGGTCTCTGTCTGGC................................................	959	20	1
............TATGGAGGTCTCTGTCTGGCT...............................................	913	21	1
..................................................TCTGATCGTTCCCCTCCGTA..........	4	20	1
..................................................TCTGATCGTTCCCCTCCGTAC.........	11	21	1
..................................................TCTGATCGTTCCCCTCCGTACA........	21	22	1
..................................................TCTGATCGTTCCCCTCCGTACAG.......	12	23	1
negative
>ACA56 chrX_154003273_154003401_+
GCAACAGTAAGTGGTGAGTTCTTCTGTCCAGCGTCAGTATTTTGATGGTGGCTTTAGACTTGCCAGATAACACTACA
...........(((..(((.((...(.(((.((((((....)))))).))))...)))))..)))............ (-22.90)
.........AGTGGTGAGTTCTTCTGTCCAG..............................................	4	22	1
.........AGTGGTGAGTTCTTCTGTCCAGC.............................................	29	23	1
..........GTGGTGAGTTCTTCTGTCCAG..............................................	1	21	1
..........GTGGTGAGTTCTTCTGTCCAGC.............................................	20	22	1
...........TGGTGAGTTCTTCTGTCCAGC.............................................	3	21	1
...........TGGTGAGTTCTTCTGTCCAGCGT...........................................	1	23	1
.............................................TGGTGGCTTTAGACTTGCCAGA..........	17	22	1
..............................................GGTGGCTTTAGACTTGCCAGA..........	3	21	1
negative
>ACA3 chr11_8705774_8705903_+
CGAAGAGTAACTGCTGACCTTATTCACTGGCTGTGGGCCTTATGGCACAGTCAGTCACCAGGTTAGAGACATGCTTCAC
.((((.....((.(((((((.....(((((((((..(((....))))))))))))....))))))))).....)))).. (-31.00)
.......TAACTGCTGACCTTATTCACT...................................................	2	21	1
.......TAACTGCTGACCTTATTCACTGG.................................................	1	23	1
........AACTGCTGACCTTATTCACTGGC................................................	4	23	1
.........ACTGCTGACCTTATTCACTGG.................................................	1	21	1
.........ACTGCTGACCTTATTCACTGGC................................................	3	22	1
..........CTGCTGACCTTATTCACTGGC................................................	4	21	1
..........CTGCTGACCTTATTCACTGGCT...............................................	1	22	1
..................................................TCAGTCACCAGGTTAGAGACATG......	2	23	1
..................................................TCAGTCACCAGGTTAGAGACATGC.....	326	24	1
...................................................CAGTCACCAGGTTAGAGACATG......	13	22	1
...................................................CAGTCACCAGGTTAGAGACATGC.....	999	23	1
....................................................AGTCACCAGGTTAGAGACATG......	7	21	1
....................................................AGTCACCAGGTTAGAGACATGC.....	461	22	1
negative
>ACA50 
CATAAGCACTGCCTTTGAACCTGATGTGTCTTGTTTGTAGCTTCACGGGCCAAGCAACAGTGCTAGAGCATAACGACT
....(((((((..((((..(((((.((..(......)..)).))).))..))))...))))))).............. (-18.10)
..TAAGCACTGCCTTTGAACCTGATGT...................................................	14	25	1
..TAAGCACTGCCTTTGAACCTGATGTG..................................................	333	26	1
...AAGCACTGCCTTTGAACCTGATGTG..................................................	3579	25	1
....AGCACTGCCTTTGAACCTGATGTG..................................................	34	24	1
..........................................TCACGGGCCAAGCAACAGTGCT..............	1	22	1
..........................................TCACGGGCCAAGCAACAGTGCTA.............	1	23	1
...........................................CACGGGCCAAGCAACAGTGCT..............	2	21	1
...........................................CACGGGCCAAGCAACAGTGCTAG............	2	23	1
............................................ACGGGCCAAGCAACAGTGCTAG............	27	22	1
............................................ACGGGCCAAGCAACAGTGCTAGA...........	30	23	1
negative


>hsa-mir-1983
GGCCAAGCAAAGGAAAGCATGCTCCAGTGGCGCAATCGGTTAGCGCGCGGTACTTATACAACAGTATATGTGCGGGTGATGCCGAGGTTGTGAGTTCGAGCCTCACCTGGAGCATGTTTTCTTCCAATTGCGAT
..........((((((((((((((((...((((...........)))).((((.(((((....))))).)))).(((((.((((((........)))).)).)))))))))))))))))))))........... (-63.3)   tRNA
......(((((((((((((((((((((.((((((((((((...(((.((.(((.(((((....))))).))))).)))..)))))..))))........)))....)))))))))))))))))....))))... (-61.33)  miRNA
.............AAAGCATGCTCCAGTGGCGC.....................................................................................................	1	20	2
....................GCTCCAGTGGCGCAATCG................................................................................................	153	18	8
....................GCTCCAGTGGCGCAATCGG...............................................................................................	8082	19	8
....................GCTCCAGTGGCGCAATCGGT..............................................................................................	977	20	8
....................GCTCCAGTGGCGCAATCGGTT.............................................................................................	17	21	8
....................GCTCCAGTGGCGCAATCGGTTA............................................................................................	1	22	8
....................GCTCCAGTGGCGCAATCGGTTAG...........................................................................................	24	23	8
....................GCTCCAGTGGCGCAATCGGTTAGC..........................................................................................	18	24	8
....................GCTCCAGTGGCGCAATCGGTTAGCG.........................................................................................	154	25	7
....................GCTCCAGTGGCGCAATCGGTTAGCGC........................................................................................	20	26	7
....................GCTCCAGTGGCGCAATCGGTTAGCGCG.......................................................................................	2	27	7
....................GCTCCAGTGGCGCAATCGGTTAGCGCGC......................................................................................	4	28	7
....................GCTCCAGTGGCGCAATCGGTTAGCGCGCG.....................................................................................	5	29	7
....................GCTCCAGTGGCGCAATCGGTTAGCGCGCGG....................................................................................	13	30	7
.......................................................................................TTGTGAGTTCGAGCCTCACCTGGAG......................	3	25	3
.......................................................................................TTGTGAGTTCGAGCCTCACCTGGAGCA....................	2	27	3
........................................................................................TGTGAGTTCGAGCCTCACCTGGAGC.....................	1	25	3
........................................................................................TGTGAGTTCGAGCCTCACCTGGAGCA....................	1	26	3
.........................................................................................GTGAGTTCGAGCCTCACCTGG........................	1	21	3
..........................................................................................TGAGTTCGAGCCTCACCTGGAG......................	2	22	3
..........................................................................................TGAGTTCGAGCCTCACCTGGAGCATGTTTT..............	1	30	1
...........................................................................................GAGTTCGAGCCTCACCTGG........................	1	19	3
...........................................................................................GAGTTCGAGCCTCACCTGGA.......................	1	20	3
...........................................................................................GAGTTCGAGCCTCACCTGGAG......................	1	21	3
...........................................................................................GAGTTCGAGCCTCACCTGGAGC.....................	1	22	3
...........................................................................................GAGTTCGAGCCTCACCTGGAGCA....................	1	23	3
...........................................................................................GAGTTCGAGCCTCACCTGGAGCATGTTTT..............	1	29	1
............................................................................................AGTTCGAGCCTCACCTGG........................	6	18	3
............................................................................................AGTTCGAGCCTCACCTGGA.......................	4	19	3
............................................................................................AGTTCGAGCCTCACCTGGAG......................	4	20	3
............................................................................................AGTTCGAGCCTCACCTGGAGC.....................	4	21	3
.............................................................................................GTTCGAGCCTCACCTGGA.......................	2	18	3
.............................................................................................GTTCGAGCCTCACCTGGAG......................	7	19	3
.............................................................................................GTTCGAGCCTCACCTGGAGC.....................	4	20	3
.............................................................................................GTTCGAGCCTCACCTGGAGCA....................	1	21	3
.............................................................................................GTTCGAGCCTCACCTGGAGCATGTTTT..............	1	27	1
..............................................................................................TTCGAGCCTCACCTGGAG......................	7	18	3
..............................................................................................TTCGAGCCTCACCTGGAGC.....................	1	19	3
..............................................................................................TTCGAGCCTCACCTGGAGCA....................	3	20	3
...............................................................................................TCGAGCCTCACCTGGAGC.....................	1	18	3
...............................................................................................TCGAGCCTCACCTGGAGCA....................	1	19	3
...............................................................................................TCGAGCCTCACCTGGAGCATGTT................	1	23	1
...............................................................................................TCGAGCCTCACCTGGAGCATGTTTTCTT...........	1	28	1
................................................................................................CGAGCCTCACCTGGAGCATGTTT...............	1	23	1
...................................................................................................GCCTCACCTGGAGCATGTTTTCT............	1	23	1
....................................................................................................CCTCACCTGGAGCATGTT................	1	18	1
....................................................................................................CCTCACCTGGAGCATGTTT...............	5	19	1
....................................................................................................CCTCACCTGGAGCATGTTTT..............	1	20	1
....................................................................................................CCTCACCTGGAGCATGTTTTC.............	3	21	1
....................................................................................................CCTCACCTGGAGCATGTTTTCT............	12	22	1
.....................................................................................................CTCACCTGGAGCATGTTT...............	1	18	2
.....................................................................................................CTCACCTGGAGCATGTTTT..............	13	19	2
.....................................................................................................CTCACCTGGAGCATGTTTTC.............	9	20	2
.....................................................................................................CTCACCTGGAGCATGTTTTCT............	176	21	1
.....................................................................................................CTCACCTGGAGCATGTTTTCTT...........	23	22	1
.....................................................................................................CTCACCTGGAGCATGTTTTCTTC..........	1	23	1
......................................................................................................TCACCTGGAGCATGTTTTCT............	10	20	1
......................................................................................................TCACCTGGAGCATGTTTTCTT...........	10	21	1
......................................................................................................TCACCTGGAGCATGTTTTCTTC..........	4	22	1
.......................................................................................................CACCTGGAGCATGTTTTC.............	1	18	2
.......................................................................................................CACCTGGAGCATGTTTTCT............	1	19	1
.......................................................................................................CACCTGGAGCATGTTTTCTT...........	3	20	1
........................................................................................................ACCTGGAGCATGTTTTCTT...........	1	19	1
.........................................................................................................CCTGGAGCATGTTTTCTT...........	2	18	2
..........................................................................................................CTGGAGCATGTTTTCTTC..........	2	18	1

>tRNA5-PseudoTTA
AGGGAGGCTGCCGAGGCAGCCTGGCTTAGTGGAAAGGGAATAGGCTTTAGAGCCAGACTGCCTGGGTTTGAATCCCAGCCCCGCCACC
.((((....(((.((((((.((((((((((.............)))...))))))).)))))).))).....))))............ -36.40
..............................................TTAGAGCCAGACTGCCTG........................ 1  18  10
..............................................TTAGAGCCAGACTGCCTGGGT..................... 3  21   3
..............................................TTAGAGCCAGACTGCCTGGGTTT................... 8  23   1
..............................................TTAGAGCCAGACTGCCTGGGTTTG.................. 2  24   1