The Relationship Between Long-Range Chromatin Occupancy and Polymerization of the Drosophila ETS Family Transcriptional Repressor Yan

Files in this data supplement:

  • Supporting Information: Figures S1-S8 and Tables S1-S10 (PDF, 12.8 MB)
  • Figure S1: Yan binds to Introns and Intergenic regions (PDF, 878 KB)
  • Figure S2: Specificity of Yan antibody (PDF, 3 MB)
  • Figure S3: ChIP patterns following immunoprecipitation of GFP-tagged YanWT with a GFP antibody (PDF, 479 KB)
  • Figure S4: Validation of sonication efficiency (PDF, 931 KB)
  • Figure S5: Yan protein levels in 6X, WT and V105R embryos (PDF, 3 MB)
  • Figure S6: YanV105R has a reduced ability to repress endogenous eve expression (PDF, 5.1 MB)
  • Figure S7: Quantification of YanV105R coverage of wild-type Yan high-density regions (PDF, 486 KB)
  • Figure S8: Assigning High density regions (HDRs) (PDF, 873 KB)
  • Table S1: Summary of Yan datasets (PDF, 107 KB)
  • Table S2: List of putative Yan target genes (PDF, 1.1 MB)
  • Table S3: Yan putative targets identified in EGFR perturbation microarrays (Butchar, 2012 #120;Jordan, 2005 #121)(PDF, 87 KB)
  • Table S4: Yan binding is dynamic across the segmentation network (PDF, 93 KB)
  • Table S5: GO analysis of Yan datasets (PDF, 255 KB)
  • Table S6: PANTHER analysis of Yan datasets (PDF, 72 KB)
  • Table S7: GO analysis implicates Yan HDRs in multiple aspects of development (PDF, 175 KB)
  • Table S8: DREME analysis of Yan bound regions (PDF, 69 KB)
  • Table S9: Yan reporters contain ETS and MAD motifs (PDF, 72 KB)
  • Table S10: List of primers used for ChIP qPCR (PDF, 80 KB)